Jean-Didier Cavallo

Antibiotic Susceptibilities of 96 Isolates of Bacillus anthracis Isolated in France between 1994 and 2000

ABSTRACT Ninety-six isolates of Bacillus anthracis recovered in France between 1994 and 2000 were tested for their susceptibilities to 25 different antibiotics. Resistance to penicillin G and amoxicillin was 11.5%. All of the isolates were resistant to cotrimoxazole and susceptible to doxycycline, ciprofloxacin, pefloxacin, levofloxacin, teicoplanin, vancomycin, clindamycin, imipenem, and rifampin.

Antibiotic Susceptibility and Mechanisms of Erythromycin Resistance in Clinical Isolates of Streptococcus agalactiae: French Multicenter Study

ABSTRACT Among 126 Streptococcus agalactiae isolates collected in 10 French laboratories in 1999, 27 (21.4%) had macrolide resistance related to the presence of erm(B) (11 strains),erm(A) subclass erm(TR) (10 strains), andmef(A) genes (2 strains) and the presence of combinations of erm(B) and erm(A) genes ormef(A) genes (3 strains).

Pseudomonas aeruginosa et infections urinaires en pratique de ville : étude AFORCOPIBIO 1995-1996

Summary 32 P. aeruginosa strains were collected by ten private clinical laboratories in patients with community-acquired urinary tract infections during a prospective multicenter study performed during two 2-month periods (May and June) in 1995 and 1996. All non hospitalised patients in the past 3 months were included. Minimal inhibitory concentrations were determined by Mueller Hinton agar dilution for ticarcillin, piperacillin, ceftazidime, imipenem, ciprofloxacin, amikacin, and fosfomycin. Mechanisms of resistance were determined for all β-lactam resistant strains by iso-electric focusing, and when a strain did not produce penicillinase, the specific β-lactamase activity was quantified. P. aeruginosa was unfrequently isolated (1.5%). The highest rates of susceptibility were shown for ceftazidime and imipenem (respectively 96.9% and 90.6%). Susceptibility was lower for ticarcillin (50%), piperacillin (84.3%), fluoroquinolones (56.2%), amikacin (62.5%), and fosfomycin (62.5%). Two resistance mechanisms to β-lactams were involved in P. aeruginosa : non enzymatic resistance (9 strains) and production of penicillinase PSE-1 (7 strains).