Jean-Guy Boiteau

Formation of dissymmetric eight-membered silalketals by ring-closing metathesis and their conversion to spiroketals

Eight-membered unsymmetrical silalketals are formed by RCM of mixed allyl/homoallyl silalketals. They are crucial intermediates in a short synthetic sequence to spiroketals illustrated in this paper by the synthesis of the C28–C38 portion of okadaic acid.

Cyclic phosphonomethylphosphinates: a new type of phosphorus-containing sugars

Abstract The first synthesis of arabino -configured cyclic phosphonomethylphosphinates is described. The key step is the condensation of the triethylester of H -phosphinylphosphonate 10 on an hydroxyaldehyde 11 derived from a d -arabinal derivative followed by a cyclization induced under acetylation conditions.