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Dive into the research topics where Jean-Luc Bridot is active.

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Featured researches published by Jean-Luc Bridot.


Journal of Materials Chemistry | 2009

Hybrid gadolinium oxide nanoparticles combining imaging and therapy

Jean-Luc Bridot; David Daydé; Charlotte Rivière; Céline A. Mandon; Claire Billotey; Stéphanie Lerondel; Roland Sabattier; Guillaume Cartron; Alain Le Pape; G. Blondiaux; Marc Janier; Pascal Perriat; Stéphane Roux; Olivier Tillement

The cytotoxicity of luminescent paramagnetic gadolinium oxide nanoparticles activated by harmless thermal neutron irradiation was evaluated on a luciferase coding gene transfected lymphome cells (EL4-Luc). Cellular uptake of nanoparticles was determined by fluorescence and magnetic resonance imaging and by ICP-MS analyses while the metabolic activity of irradiated EL4-Luc cells was monitored by bioluminescence. The alteration of the irradiated cells depends both on neutron irradiation dose and on gadolinium content within cells. In addition to their dual modality imaging ability, the application of these multifunctional particles for neutron capture therapy can be envisaged.


Journal of the American Chemical Society | 2007

Hybrid Gadolinium Oxide Nanoparticles: Multimodal Contrast Agents for in Vivo Imaging

Jean-Luc Bridot; Anne-Charlotte Faure; Sophie Laurent; Charlotte Rivière; Claire Billotey; Bassem Hiba; Marc Janier; Véronique Josserand; Jean-Luc Coll; Luce Vander Elst; Robert N. Muller; Stéphane Roux; Pascal Perriat; Olivier Tillement


Chemistry of Materials | 2005

Nanosized Hybrid Particles with Double Luminescence for Biological Labeling

Cédric Louis; Rana Bazzi; Christophe A. Marquette; Jean-Luc Bridot; Stéphane Roux; Gilles Ledoux; Bruno Mercier; Loïc J. Blum; and Pascal Perriat; Olivier Tillement


Langmuir | 2005

Synthesis, characterization of dihydrolipoic acid capped gold nanoparticles, and functionalization by the electroluminescent luminol.

Stéphane Roux; Bruno Garcia; Jean-Luc Bridot; Murielle Salomé; Christophe A. Marquette; Laurence Lemelle; Philippe Gillet; Loïc J. Blum; Pascal Perriat; Olivier Tillement


Future Medicinal Chemistry | 2010

Magnetic iron oxide nanoparticles for biomedical applications

Sophie Laurent; Jean-Luc Bridot; Luce Vander Elst; Robert N. Muller


Journal of Nanoparticle Research | 2010

High quality and tuneable silica shell–magnetic core nanoparticles

Carmen Vogt; Muhammet S. Toprak; Mamoun Muhammed; Sophie Laurent; Jean-Luc Bridot; Robert N. Muller


Imaging in Medicine | 2010

Multifunctional gadolinium oxide nanoparticles: towards image-guided therapy

Stéphane Roux; Anne-Charlotte Faure; Céline A. Mandon; Sandrine Dufort; Charlotte Rivière; Jean-Luc Bridot; Brice Mutelet; Christophe A. Marquette; Véronique Josserand; Géraldine Le Duc; Alain Le Pape; Claire Billotey; Marc Janier; Jean-Luc Coll; Pascal Perriat; Olivier Tillement


Chemical Communications | 2005

Sulfur K-edge XANES study of dihydrolipoic acid capped gold nanoparticles: dihydrolipoic acid is bound by both sulfur ends

Bruno Garcia; Murielle Salomé; Laurence Lemelle; Jean-Luc Bridot; Phillipe Gillet; Pascal Perriat; Stéphane Roux; Olivier Tillement


Contrast Media & Molecular Imaging | 2007

CMR 2007: 7.07: Hybrid gadolinium oxide nanoparticles: contrast agents combining diagnosis and therapy

Jean-Luc Bridot; D. Dayde; Anne-Charlotte Faure; Sophie Laurent; Charlotte Rivière; Claire Billotey; Bassem Hiba; Marc Janier; Véronique Josserand; Jean-Luc Coll; L. Vander Elst; Robert N. Muller; R. Sabattier; S. Lerondel; A. Lepape; Pascal Perriat; Stéphane Roux; Olivier Tillement


Archive | 2010

Biocompatibility of tuneable silica shell-magnetic core nanoparticles evaluated in vitro using primary human monocute-derived macrophages

Carmen Vogt; Andrea Kunzmann; Neus Feliu Torres; Tina Thurnherr; Sophie Laurent; Jean-Luc Bridot; Robert N. Muller; Muhammet S. Toprak; Harald F. Krug; Bengt Fadeel; Mamoun Muhammed

Collaboration


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Stéphane Roux

University of Franche-Comté

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Carmen Vogt

Royal Institute of Technology

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Muhammet S. Toprak

Royal Institute of Technology

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Luce Vander Elst

University of Mons-Hainaut

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Bassem Hiba

University of Bordeaux

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