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Dive into the research topics where Jean-Marie Receveur is active.

Publication


Featured researches published by Jean-Marie Receveur.


Bioorganic & Medicinal Chemistry Letters | 1999

Synthesis and biological evaluation of conformationally restricted Gabapentin analogues.

Jean-Marie Receveur; Justin Stephen Bryans; Mark J. Field; Lakhbir Singh; David C. Horwell

A series of conformationally restricted Gabapentin analogues has been synthesised. The pyrrolidine analogue (R)-2-Aza-spiro[4.5]decane-4-carboxylic acid hydrochloride (3a) had an IC50 of 120 nM, similar to that of Gabapentin (IC50 = 140 nM), at the Gabapentin binding site on the alpha2delta subunit of a calcium channel. Compound (3a) also reversed carrageenan induced hyperalgesia in rats.


Archive | 1999

Conformationally constrained amino acid compounds having affinity for the alpha2delta subunit of a calcium channel

Justin Stephen Bryans; David Christopher Horwell; Jean-Marie Receveur


Archive | 1999

Branched alkyl pyrrolidine-3-carboxylic acids

Justin Stephen Bryans; Ihoezo Victor Ekhato; David Christopher Horwell; Rong Ling; Jean-Marie Receveur; David Juergen Wustrow


Archive | 2001

Conformationally constrained compounds as pharmaceutical agents

Justin Stephen Bryans; David Christopher Horwell; Jean-Marie Receveur


Archive | 2003

Bicyclic amino acid as pharmaceutical agent

David C. Blakemore; Justin Stephen Bryans; Simon Osborne; Jean-Marie Receveur; サイモン・オズボーン; ジャスティン・スティーブン・ブライアンズ; ジャン−マリー・レスヴェール; デイヴィッド・クライヴ・ブレイクモア


Archive | 2000

A bicyclic amino acids as pharmaceutical products

Clive David Blakemore; Justin Stephen Bryans; Simon Stetchworth-Newmarket Osborne; Jean-Marie Receveur


Archive | 2000

Bicyclic amino acids useful as pharmaceutical agents

Justin Stephen Bryans; David C. Blakemore; Simon Osborne; Jean-Marie Receveur


Archive | 2000

Bicyclische aminosäuren als pharmazeutische mittel Bicyclic amino acids as pharmaceutical medium

Clive David Blakemore; Justin Stephen Bryans; Simon Stetchworth-Newmarket Osborne; Jean-Marie Receveur


Archive | 1999

Acides pyrrolidine-3-carboxyliques d'alkyle ramifie

Justin Stephen Bryans; Ihoezo Victor Ekhato; David Christopher Horwell; Rong Ling; Jean-Marie Receveur; David Juergen Wustrow


Archive | 1999

Composes d'acide amines soumis a une contrainte de conformation et presentant une affinite pour la sous-unite alpha 2 delta d'un canal calcique

Justin Stephen Bryans; David Christopher Horwell; Jean-Marie Receveur

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