Network


Latest external collaboration on country level. Dive into details by clicking on the dots.

Hotspot


Dive into the research topics where Jean-Paul Castaigne is active.

Publication


Featured researches published by Jean-Paul Castaigne.


Bioorganic & Medicinal Chemistry Letters | 2003

Synthesis and In Vitro Analysis of Atrial Natriuretic Peptide-Albumin Conjugates

Roger Leger; Martin Robitaille; Omar Quraishi; Elizabeth Denholm; Corinne Benquet; Julie Carette; Pieter van Wyk; Isabelle Pellerin; Nathalie Bousquet-Gagnon; Jean-Paul Castaigne; Dominique P. Bridon

Atrial natriuretic peptide (ANP) is a clinically useful anti-hypertensive hormone. Maleimide derivatives of ANP have been synthesized and conjugated to cysteine-34 of human serum albumin. The conjugates were analyzed to assess their stability, receptor binding affinity and ability to stimulate guanylyl-cyclase activity in rat lung fibroblasts.


Diabetes | 2003

Development and Characterization of a Glucagon-Like Peptide 1-Albumin Conjugate: The Ability to Activate the Glucagon-Like Peptide 1 Receptor In Vivo

Jung-Guk Kim; Laurie L. Baggio; Dominique P. Bridon; Jean-Paul Castaigne; Martin Robitaille; Lucie Jetté; Corinne Benquet; Daniel J. Drucker


Bioorganic & Medicinal Chemistry Letters | 2004

Identification of CJC-1131-albumin bioconjugate as a stable and bioactive GLP-1(7–36) analog

Roger Leger; Karen Thibaudeau; Martin Robitaille; Omar Quraishi; Pieter van Wyk; Nathalie Bousquet-Gagnon; Julie Carette; Jean-Paul Castaigne; Dominique P. Bridon


Archive | 2006

Method of treatment of diabetes and/or obesity with reduced nausea side effect

Dominique P. Bridon; Jean-Paul Castaigne; Karen Thibaudeau


Bioconjugate Chemistry | 2005

Synthesis and evaluation of insulin-human serum albumin conjugates.

Karen Thibaudeau; Roger Leger; Xicai Huang; Martin Robitaille; Omar Quraishi; Chantal Soucy; Nathalie Bousquet-Gagnon; Pieter van Wyk; Véronique Paradis; Jean-Paul Castaigne; Dominique P. Bridon


Archive | 2004

Long lasting insulin derivatives and methods thereof

Dominique P. Bridon; Jean-Paul Castaigne; Xicai Huang; Roger Leger; Martin Robitaille


Archive | 2006

Method of treating diabetes and/or obesity with reduced nausea side effects using an insulinotropic peptide conjugated to albumin

Dominique P. Bridon; Jean-Paul Castaigne; Karen Thibodeau


Archive | 2004

Derivatives of long-acting insulin and associated procedures.

Dominique P. Bridon; Jean-Paul Castaigne; Xicai Huang; Roger Leger; Martin Robitaille


Archive | 2004

Derives de l'insuline longue duree et procedes associes

Dominique P. Bridon; Jean-Paul Castaigne; Xicai Huang; Roger Leger; Martin Robitaille


Archive | 2004

Insulinderivative mit langanhaltender wirkung und verfahren zu deren herstellung Insulinderivative with long-lasting effect and process for their preparation

Dominique P. Bridon; Jean-Paul Castaigne; Xicai Huang; Roger Leger; Martin Robitaille

Collaboration


Dive into the Jean-Paul Castaigne's collaboration.

Top Co-Authors

Avatar

Roger Leger

Université de Montréal

View shared research outputs
Top Co-Authors

Avatar
Researchain Logo
Decentralizing Knowledge