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Dive into the research topics where Jean-Paul Martin is active.

Publication


Featured researches published by Jean-Paul Martin.


Archive | 2001

From Random Screening of Chemical Libraries to the Optimization of FPP-Competitive Inhibitors of Farnesyltransferase

Patrick Mailliet; Abdel Laoui; Jean-Dominique Bourzat; Marc Capet; Michel Cheve; Alain Commercon; Norbert Dereu; Alain Lebrun; Jean-Paul Martin; Jean-Francois Peyronel; Christophe Salagnad; Fabienne Thompson; Martine Zucco; Jean-Dominique Guitton; Guy Pantel; Marie-Christine Bissery; Clive Brealey; Jacques Lavayre; Yves Lelièvre; Jean-François Riou; Patricia Vrignaud; Marc Duchesne; François Lavelle

Together with gene alterations of the p53 tumor suppressor gene, mutations of the ras genes represent the most frequent gene modification umancancers. Ras mutations are found in at least 90% of pancreas, 50% of colon, and 30% of both lung and thyroid cancers (1,2).


Archive | 1999

Farnesyl transferase inhibitors, their preparation, the pharmaceutical compositions which contain them and their use in the preparation of medicaments

Jean-Dominique Bourzat; Alain Commerçon; Norbert Dereu; Patrick Mailliet; Fabienne Sounigo-Thompson; Jean-Paul Martin; Marc Capet; Michel Cheve


Archive | 1990

Benzopyran derivatives, their preparation and pharmaceutical compositions containing them

Michel Barreau; Jean-Claude Hardy; Jean-Paul Martin; Christian Renault


Archive | 1994

Pyrrolidine and thiazolidine derivatives, their preparation and drugs containing same

Marc Capet; Marie-Christine Dubroeucq; Franco Manfre; Jean-Paul Martin


Archive | 1990

Benzopyrane derivatives, their preparation and pharmaceutical compositions containing them

Michel Barreau; Jean-Claude Hardy; Jean-Paul Martin; Christian Renault


Archive | 2004

4-substituted quinolein derivatives with antimicrobial activity

Antony Bigot; Michel Cheve; Ahmad Youssef El; Jean-Luc Malleron; Jean-Paul Martin; Serge Mignani; Guy Pantel; Baptiste Ronan; Michel Tabart; Fabrice Viviani


Archive | 1992

3-Ureidobenzodiazepinones useful as antagonists of CCK or of gastrin

Marc Capet; Claude Cotrel; Marie-Christine Dubroeuco; Claude Guyon; Jean-Paul Martin


Archive | 1992

3-ureido-benzodiazepinones useful as CCK or gastrin antagonists

Marc Capet; Claude Cotrel; Marie-Christine Dubroeucq; Claude Guyon; Jean-Paul Martin


Archive | 2004

3-(guanidinocarbonyl)heterocycle derivatives, preparation process and intermediates of this process, their use as medicaments, and pharmaceutical compositions including them

Jean-Christophe Carry; Gilles Doerflinger; Arielle Genevois-Borella; Michel Evers; Brun Alain Le; Jean-Paul Martin; Pascal Desmazeau; Serge Mignani; Heinz-Werner Kleemann


Archive | 1995

Neurotensin antagonist peptides

Francois-Frederic Clerc; Marie-Christine Dubroeucq; Gerard Helynck; Jean Leboul; Jean-Paul Martin

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Serge Mignani

University of Wisconsin-Madison

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