Jeferson de Oliveira Salvi

USO DE METILFENIDATO ENTRE ACADÊMICOS NO INTERIOR DE RONDÔNIA DOI: http://dx.doi.org/10.5892/ruvrd.v15i1.2963

In recent years visible is the increase in consumption of psychotropic drugs, including methylphenidate, which in many cases are used by students to improve learning. This study aimed to characterize the profile of the use of methylphenidate among academics of a university located in the state of Rondonia. They constituted the study 150 students coming from biomedicine courses, nursing and pharmacy. Patients were predominantly female, the majority of respondents had taken the course of pharmacology, however only 48% could define psychotropic medications. Regarding the use of methylphenidate 18% said they already have it practiced, and of these 45% have purchased it with a prescription. The main reason for usage was to improve learning (85%), where most of the scholars said they have achieved the desired effect, while 59% reported adverse effects. The data show the use of methylphenidate to obtain improvement in student performance, trend observed in other studies, which have brought concern the public health context.

Análise fitoquímica e das atividades citotóxica, antioxidante, e antibacteriana das flores de Tabebuia serratifolia (Vahl) Nicholson

The present study aimed to analyze the phytochemical compounds, and evaluate the cytotoxic, antioxidant and antimicrobial activities of Tabebuia serratifolia flowers. The phytochemical analysis was performed using qualitative colorimetric tests, the cytotoxicity by the Artemia salina lethality test, the antioxidant activity was evaluated by the ability to deactivate the 2.2-diphenyl-1-picrylhydrazyl radical (DPPH) and the antibacterial activity was evaluated by the disc diffusion method, against the microorganisms Escherichia coli, Staphylococcus aureus and Shigella sp. The results revealed the presence of flavonoids, saponins and triterpenes or steroids. It was observed the cytotoxicity (LD50=679 µg/mL), antioxidant activity (EC50=86 mg/mL) and antibacterial activity on all strains tested.