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Jeffrey D. Scholten

Pfizer

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Featured researches published by Jeffrey D. Scholten.

Biochemistry | 1992

Ancestry of the 4-chlorobenzoate dehalogenase: analysis of amino acid sequence identities among families of acyl:adenyl ligases, enoyl-CoA hydratases/isomerases, and acyl-CoA thioesterases.

Patricia C. Babbitt; George L. Kenyon; Brian M. Martin; Hugues Charest; Michel Slyvestre; Jeffrey D. Scholten; Kai Hsuan Chang; Po Huang Liang; Debra Dunaway-Mariano

Biochemistry | 1992

Isolation and characterization of the three polypeptide components of 4-chlorobenzoate dehalogenase from Pseudomonas sp. strain CBS-3

Kai Hsuan Chang; Po Haung Liang; Wendie Beck; Jeffrey D. Scholten; Debra Dunaway-Mariano

Biochemistry | 1996

Mutations in the B12-Binding Region of Methionine Synthase: How the Protein Controls Methylcobalamin Reactivity†

Joseph T. Jarrett; Mohan Mark Amaratunga; Catherine L. Drennan; Jeffrey D. Scholten; Richard H. Sands; Martha L. Ludwig; Rowena G. Matthews

Journal of Medicinal Chemistry | 1997

Structure-activity relationships of cysteine-lacking pentapeptide derivatives that inhibit ras farnesyltransferase

Daniele Leonard; Kevon R. Shuler; Cynthia J. Poulter; Scott R. Eaton; Tomi K. Sawyer; John C. Hodges; Ti Zhi Su; Jeffrey D. Scholten; Richard Gowan; Judith Sebolt-Leopold; Annette M. Doherty

Journal of Medicinal Chemistry | 1997

C-terminal modifications of histidyl-N-benzylglycinamides to give improved inhibition of Ras farnesyltransferase, cellular activity, and anticancer activity in mice.

Dennis Joseph Mcnamara; Ellen M. Dobrusin; Daniele Leonard; Kevon R. Shuler; James Stanley Kaltenbronn; John Quin; Scott Bur; Charles E. Thomas; Annette M. Doherty; Jeffrey D. Scholten; Karen K. Zimmerman; Barbara S. Gibbs; Richard Gowan; Michael P. Latash; Wilbur R. Leopold; Sally Przybranowski; Judith Sebolt-Leopold

Journal of Biological Chemistry | 2001

Conserved Cysteine and Tryptophan Residues of the Endothelin-converting Enzyme-1 CXAW Motif Are Critical for Protein Maturation and Enzyme Activity

Kathryn J. MacLeod; Robert S. Fuller; Jeffrey D. Scholten; Kyunghye Ahn

Biochemistry | 1996

A synthetic module for the metH gene permits facile mutagenesis of the cobalamin-binding region of Escherichia coli methionine synthase: Initial characterization of seven mutant proteins

Mohan Mark Amaratunga; Kerry Fluhr; Joseph T. Jarrett; Catherine L. Drennan; Martha L. Ludwig; Rowena G. Matthews; Jeffrey D. Scholten

Bioorganic & Medicinal Chemistry Letters | 2006

The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases.

Lain Yen Hu; Suzanne Ross Kesten; Huangshu J. Lei; David Juergen Wustrow; David W. Moreland; Liming Zhang; Kay Ahn; Todd R. Ryder; Xiaohong Liu; John Rubin; Kelly Fahnoe; Richard T. Carroll; Satavisha Dutta; Douglass C. Fahnoe; Albert W. Probert; Robin Roof; Michael F. Rafferty; Catherine Rose Kostlan; Jeffrey D. Scholten; Molly M. Hood; Xiao Dan Ren; Gerald P. Schielke; Ti Zhi Su; Charles P. Taylor; Anil Mistry; Patrick McConnell; Charles A. Hasemann; Jeffrey F. Ohren

Biochemistry | 1990

Purification and characterization of the Tetrahymena pyriformis P-C bond forming enzyme phosphoenolpyruvate phosphomutase.

Elise Bowman; Michael S. McQueney; Jeffrey D. Scholten; Debra Dunaway-Mariano

Journal of Traditional and Complementary Medicine | 2018

Evaluation of selected traditional Chinese medical extracts for bone mineral density maintenance: A mechanistic study

John F. Rebhun; Qin Du; Molly M. Hood; Hailing Guo; Kelly M. Glynn; Hao Cen; Jeffrey D. Scholten; Feng Tian; Min Gui; Minjie Li; Yongfang Zhao

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David Juergen Wustrow

Pfizer

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Lain-Yen Hu

Pfizer

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Debra Dunaway-Mariano

University of New Mexico

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Molly M. Hood

Pfizer

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Sheryl Jeanne Hays

University of Michigan

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Annette M. Doherty

Pfizer

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Catherine L. Drennan

University of Michigan

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David W. Moreland

Pfizer

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Jatinder Rana

Analytical Services

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Joseph T. Jarrett

University of Michigan

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