Jennifer Rose V. Molano

How Might Late-Life Blood Pressure Be Related to Cerebrovascular and Alzheimer Disease Pathology?

Blood pressure can contribute to cognitive decline. To investigate whether blood pressure is associated with cerebral pathology, researchers combined

Intracranial Atherosclerosis and Cognitive Status

Vascular risk factors have been associated with incident dementia, but little is known about the association between intracranial atherosclerosis and

Midlife Vascular Risk Factors and Late-Life Amyloid Deposition

Vascular risk factors have been associated with Alzheimer disease (AD). Extracellular amyloid plaques are one of the pathologic features of AD. To

Mild Cognitive Impairment — The Clinicopathological Challenge

To assess clinical and pathological outcomes of mild cognitive impairment (MCI), investigators examined data from 1337 participants from 11

The Mediterranean Diet and Structural Brain Changes

The Mediterranean diet — with high fruit, vegetable, legume, and cereal consumption; moderate fish consumption; and low red meat and poultry intake —

Systolic Blood Pressure, Cognition, and Race

Target systolic blood pressure (SBP) recommendations have ranged from <150 mm Hg for older adults to <120 mm Hg for cardiovascular risk reduction.

Rapid Eye Movement Sleep: Another Link in the Sleep–Dementia Connection

Sleep disturbances have been examined recently as a potential risk factor for dementia. In this study, investigators analyzed whether objective sleep

The Effect of Slow-Wave Sleep on Amyloid and Tau levels

Sleep disruption has been associated with Alzheimer disease pathology, and slow-wave sleep may be a key factor in amyloid and tau dynamics. These

Subjective and Objective Sleep Characteristics in Cognitive Impairment

Investigators conducted a nested case-control analysis of subjective and objective sleep characteristics in 580 Swiss participants aged >65 years with

Midlife Hypertension and Incident Dementia: Different in Women vs. Men?

Hypertension increases dementia risk (NEJM Journal Watch Neurol Oct 2017 and Lancet Jul 19 2017; [e-pub]). Researchers investigated whether