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Dive into the research topics where Jeongmin Lee is active.

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Featured researches published by Jeongmin Lee.


Asia Pacific Allergy | 2013

Sensitization patterns of cow's milk and major components in young children with atopic dermatitis.

Jeongmin Lee; Jong-Seo Yoon; Se-Ah Jeon; Soo Young Lee

Background Cows milk (CM) is one of the most common food allergens in children with atopic dermatitis (AD), and the component-specific immunoglobulin E (component-IgE) measurement has recently become available. Objective This study aimed to investigate the sensitization patterns to CM and 3 major components and their clinical values in young Korean children with AD. Methods Cows milk-specific IgE (CM-IgE), α-lactalbumin-specific IgE (ALA-IgE), β-lactoglobulin-specific IgE (BLG-IgE), and casein-specific IgE (Cas-IgE) levels from the sera of patients with AD were measured using the UniCAP™ system (Thermo Fisher Scientific, Sweden) and collected from January 2004 to December 2010. Patients ≥ 4 years of age were excluded from the analysis. Results A total of 950 patients diagnosed with AD were ultimately enrolled in the study. Among them, 471 (49.6%) patients were sensitized to CM (CM-IgE[+], > 0.35 kU/L). Sensitization to casein (n = 349, 74.1%) was most common, followed by ALA (n = 283, 60.1%), and BLG (n = 245, 52.5%). Meanwhile, 95 patients had at least 2 follow-up tests. Eighty (84.2%) of these patients tested positive to CM, and the casein sensitization rate was the highest (n = 65, 81.3%). In addition, 479 (50.4%) patients were not sensitized to CM (CM-IgE[-], ≤ 0.35 kU/L) but 35 (7.3%) patients were sensitized to at least one component. Among them, a telephone survey was accessible in 21 cases. A total of 8 (38.1%) patients still suffered from adverse reactions after consuming milk and/or dairy foods. Conclusion Casein was the most commonly and persistently sensitized component in CM-IgE(+) children with AD. Measuring CM component IgE antibodies, especially Cas-IgE, is helpful for evaluating problematic allergens in young children with AD.


Allergy, Asthma and Immunology Research | 2018

Immunoglobulin E-binding Proteins of Cooked Walnuts in Korean Children

Jeongmin Lee; Kyunguk Jeong; Se-Ah Jeon; Soo Young Lee

Purpose The immunological characteristics of young Korean children with walnut (WN) allergy and the influence of different cooking methods on WN proteins have not been evaluated to date. This study aimed to evaluate the major WN allergens identified among Korean children, together with changes in WN antigenicity caused by common cooking methods. Methods We enrolled children under the age of 13 years with WN serum-specific immunoglobulin (Ig) E concentrations. The protein fractions of dry-fried and boiled WN extracts were compared with those of raw WNs using sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE), 2-dimentional gel electrophoresis (2DE) and a proteomic analysis using electrospray ionization (liquid chromatography-mass spectrometry [LC-MS]). An immunoblotting analysis was conducted to examine IgE reactivity toward raw WNs using serum samples from 6 children with a clinical WN allergy. To determine the processed WN proteins with IgE-binding capacity, a 2D-immunoblotting analysis was performed using the pooled sera of 20 WN-sensitized children. Results Protein bands from raw WNs were identified at 9, 16, 28, 52, 58, and 64 kDa via SDS-PAGE. The 9- and 16-kDa protein bands were enhanced by boiling, whereas the 52- and 64-kDa bands were considerably diminished. On LC-MS analysis, of the 66 IgE-binding proteins present in raw WNs, 57 were found in dry-fried WNs, but only 4 in boiled WNs. The sera of 5 out of 6 participants reacted with the 52-kDa protein bands and those of 4 out of 6 participants reacted with the 16- and 28-kDa protein bands, respectively. Meanwhile, a 2D-immunoblotting result confirmed the presence of different binding patterns among children who consumed cooked WNs. Conclusions The protein profile of boiled WNs is substantially different from that of raw WNs. However, 4 proteins including prolamins remained stable after dry-frying or boiling. Further studies are needed to evaluate the clinical relevance of these findings.


Korean Journal of Asthma, Allergy and Clinical Immunology | 2012

Incidence and Clinical Characteristics of Pediatric Emergency Department Visits of Children with Severe Food Allergy

Soo Young Lee; Kyun Won Kim; Hyun Hee Lee; Dae Hyun Lim; Hae Lee Chung; Sung Won Kim; So Yeon Lee; Eun Seok Yang; Jeongmin Lee; Kyu Earn Kim


Pediatric Allergy and Respiratory Disease | 2010

A Case of Barley Anaphylaxis due to Infant's Weaning Food

Jeongmin Lee; Nam Hyang Koo; Eun Jin Kim; Soo Young Lee


Nuclear Instruments & Methods in Physics Research Section B-beam Interactions With Materials and Atoms | 1999

MEV 4HE++ CHANNELING STUDIES OF EPITAXIALLY GROWN PT FILMS ON AL2O3(0 0 0 1)

Jung Ho Song; Won-Jun Choi; Kyungkon Kim; Jeongmin Lee; Seunghye Kim; H.B. Kim; Myung-Hyun Lee; K. Jeong; C. N. Whang


Allergy, Asthma & Respiratory Disease | 2018

Epidemiology of food allergy in Korean children

Taek Ki Min; Bok Yang Pyun; Hyun Hee Kim; Yong-Mean Park; Gwang Cheon Jang; Hye Young Kim; Hye Yung Yum; Jihyun Kim; Kangmo Ahn; Soo Young Lee; Kyung Won Kim; Yoon Hee Kim; Jeongmin Lee; Woo Kyung Kim; Tae Won Song; Jeong Hee Kim; Yong Ju Lee; You Hoon Jeon; So-Yeon Lee


Allergy, Asthma & Respiratory Disease | 2015

Usefulness of casein specific IgE and IgG antibodies to immediate type cow's milk allergy

Ja Hyun Lim; Kyung Uk Jeong; Jeongmin Lee; Kyung Eun Lee; Soo Young Lee


Allergy, Asthma & Respiratory Disease | 2018

The KAAACI Standardization Committee Report on the procedure and application of the bronchial provocation tests

Kyung-Hwan Lim; Min-Hye Kim; Min-Suk Yang; Woo-Jung Song; Jae-Woo Jung; Jeongmin Lee; Dong In Suh; Yoo Seob Shin; Jae-Woo Kwon; Sae-Hoon Kim; Sang-Heon Kim; Byung-Jae Lee; Sang-Heon Cho


Allergy, Asthma & Respiratory Disease | 2017

KAAACI Standardization Committee report on the procedure and application of induced sputum examination

Min-Hye Kim; Mi-Yeong Kim; Kyung-Hwan Lim; Min-Suk Yang; Woo-Jung Song; Jeongmin Lee; Dong In Suh; Yoo Seob Shin; Jae-Woo Kwon; Sae-Hoon Kim; Sang-Heon Kim; Byung-Jae Lee; Sang-Heon Cho; Jae-Woo Jung


Allergy, Asthma & Respiratory Disease | 2017

The KAAACI Standardization Committee Report on the procedure and application of fractional exhaled nitric oxide measurement

Jae-Woo Kwon; Woo-Jung Song; Min-Hye Kim; Kyung-Hwan Lim; Min-Suk Yang; Jae-Woo Jung; Jeongmin Lee; Dong In Suh; Yoo Seob Shin; Sae-Hoon Kim; Sang-Heon Kim; Byung-Jae Lee; Sang-Heon Cho

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Dong In Suh

Seoul National University

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Jae-Woo Kwon

Kangwon National University

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Kyung-Hwan Lim

Seoul National University

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Min-Hye Kim

Ewha Womans University

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Min-Suk Yang

Seoul National University

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Sae-Hoon Kim

Seoul National University

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