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Dive into the research topics where Jerzy Czernik is active.

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Featured researches published by Jerzy Czernik.


Journal of Pediatric Surgery | 2008

Laparoscopic splenectomy in children–a multicenter experience

Maciej Murawski; Dariusz Patkowski; Wojciech Korlacki; Piotr Czauderna; Mariusz Sroka; Wojciech Makarewicz; Jerzy Czernik; Józef Dzielicki

PURPOSE Splenectomy is frequently required in children for various hematologic pathologic findings. Because of progress in minimally invasive techniques, laparoscopic splenectomy (LS) has become feasible. The objective of this report is to present a multicenter experience of 159 laparoscopic splenectomies. METHODS Records of 159 children, who underwent LS in 3 pediatric surgery centers between 1996 and 2006, were reviewed retrospectively with a special questionnaire. The indication for splenectomy were hematologic disorders (147), esophageal varices (6), splenic cyst (5), and tumor of the tail of the pancreas (1). The LS was performed using standard laparoscopic technique and instrumentation. RESULTS There were 75 boys and 84 girls. Median age was 12.5 years (range, 2-19.4 years). Laparoscopic splenectomy alone was performed in 118 cases and LS with cholecystectomy or cholecystotomy in 36. In 5 cases, LS was performed together with fundoplication. Eight LS required conversion to an open procedure for following reasons: severe bleeding (3), massive splenomegaly (1), anatomical (2), and technical aspects (2). Accessory spleens were identified in 20 cases (12.6%). There was no mortality. Complications consisted of 8 conversions and postoperatively of mild generalized infection in 3 children and abdominal bleeding that resulted in re-laparoscopy in 1 case. CONCLUSIONS Laparoscopic splenectomy can be safely and effectively performed in children.


Journal of Pediatric Surgery | 1992

The natural course of cryptorchidism in rats and the efficacy of orchidopexy or orchidectomy in its treatment before and after puberty

Dariusz Patkowski; Jerzy Czernik; Michel Jeleń

Both clinical and experimental evidence suggest that fertility is impaired in unilateral cryptorchidism. To investigate the effect of the undescended testis on the contralateral descended gonad, a new experimental model based on natural cryptorchidism in rats was designed. Seventy male Buffalo rats with an undescended right testis noted at the age of 30 days were used. Fifty healthy animals served as a controls. The natural course of cryptorchidism was investigated at the ages of 30, 90, and 180 days. The effects of orchiopexy and orchiectomy performed in cryptorchid animals before and after puberty were evaluated at the age of 180 days. Both nonoperated and operated animals were mated at the age of 150 days in order to estimate their fertility. The animals were killed at 30, 90, and 180 days of life and the testes were removed. In each excised testis testicular weight and seminiferous tubular diameters were measured and the maturity of the germinal epithelium was determined using the Johnsen testicular biopsy score. The experiment demonstrated reduced testicular weight and seminiferous tubular diameters in undescended testis already at 30 days and arrest of spermatogenesis at the spermatocytes stage at 90 and 180 days. There was no significant difference between contralateral descended testes and controls at the age of 30 and 90 days, but at 180 days the degenerative changes were identical with those in the cryptorchid testes. Cryptorchid rats were completely infertile. Both orchiopexy and orchiectomy prevented the damage to the contralateral testis. A significant improvement in size and spermatogenesis was recorded in most cases of the surgically descended testes.(ABSTRACT TRUNCATED AT 250 WORDS)


Journal of Applied Genetics | 2006

Single nucleotide polymorphisms in the RET gene and their correlations with Hirschsprung disease phenotype

Robert Śmigiel; Arleta Lebioda; Dariusz Patkowski; Jerzy Czernik; Tadeusz Dobosz; Karolina Pesz; Monika Kaczmarz; Maria M. Sąiadek

Hirschsprung disease (HSCR) is a congenital, heterogeneous disorder, characterized by the absence of intestinal ganglion cells. Recent advances show that theRET gene is a major locus involved in the pathogenesis of HSCR. The aim of this study was to analyse if the HSCR phenotype in the Polish population is associated with the presence of polymorphisms in exons 2, 3, 7, 11, 13, 14 and 15 of theRET gene. Molecular results were compared with clinical and long-term follow-up data in 70 Polish patients with HSCR (84.3% with a short segment and 15.7% with a long segment of aganglionic gut). Single-nucleotide polymorphisms were analysed by using the minisequencing SNaPshot multiplex method. The 135G>A polymorphism inRET exon 2 was overrepresented in HSCR patients, compared with a healthy control group. Moreover, the 135G>A variant was shown to be associated with the severe HSCR phenotype. Two other polymorphisms, 2071G>A in exon 11 and 2712C>G in exon 15, were underrepresented in the patients. The results confirm that theseRET polymorphisms play a role in the aetiology of HSCR.


Journal of Pediatric Surgery | 1994

Division of the genitofemoral nerve in unilateral cryptorchid rats

Dariusz Patkowski; Jerzy Czernik; Michal Jelen

The long-term effect of dividing the genitofemoral nerve supply to the undescended testis in naturally cryptorchid rats is reported. 20 male Buffalo rats with an undescended right testis, noted at the age of 30 days, were used for the investigation. 20 healthy animals served as controls. The abdominal division of the right genitofemoral nerve was performed in 10 cryptorchid and 10 healthy animals at the age of 40 days. The animals were mated at 150 days of age. Both testes were removed at 180 days of age. In each excised testis the testicular weight and seminiferous tubular diameters were measured, and the maturity of the germinal epithelium was determined using the Johnsen testiscular biopsy score. The experiment showed that in 70% of the nonoperated cryptorchid rats, both testes were affected at the age of 180 days, and 90% of these animals were infertile. In the operated cryptorchid rats, the contralateral descended were not damaged, and 60% of these animals were fertile. The division of the genitofemoral nerve in healthy animals had no effect. The results suggest that neural transmissions might play a role in the damage to the descended testis in unilateral cryptorchidism. This observation requires further investigations.


Pediatria polska | 2007

Olbrzymi tłuszczak okolicy zaotrzewnowej u 3-letniej dziewczynki – opis przypadku ☆

Jolanta Ładogórska; Wojciech Apoznański; Jerzy Czernik; Konrad Rysiakiewicz

Tluszczaki (lipoma) są lagodnymi guzami czesto wystepującymi u osob doroslych, ale rowniez u nastolatkow, szczegolnie w lokalizacji konczynowej. Wystąpienie tluszczaka z dojrzalych komorek tluszczowych u dziecka przed 10 rokiem zycia mozna uznac za przypadek nietypowy. Celem pracy jest przedstawienie sposobu diagnostyki oraz leczenia dziewczynki z olbrzymich rozmiarow tluszczakiem przestrzeni zaotrzewnowej oraz omowienie aktualnego stanu wiedzy na temat guzow zbudowanych z komorek tluszczowych.


Journal of Laparoendoscopic & Advanced Surgical Techniques | 2006

Percutaneous internal ring suturing: a simple minimally invasive technique for inguinal hernia repair in children.

Dariusz Patkowski; Jerzy Czernik; Rafalł Chrzan; Wojciech Jaworski; Wojciech Apoznański


Journal of Laparoendoscopic & Advanced Surgical Techniques | 2008

Thoracoscopic repair of tracheoesophageal fistula and esophageal atresia.

Dariusz Patkowski; Konrad Rysiakiewicz; Wojciech Jaworski; Marzena Zielińska; Grazyna Siejka; Katarzyna Konsur; Jerzy Czernik


Journal of Laparoendoscopic & Advanced Surgical Techniques | 2007

Laparoscopic splenectomy in children: experience in a single institution.

Dariusz Patkowski; Rafal Chrzan; Grazyna Wrobel; Agnieszka Sokół; Grzegorz Dobaczewski; Wojciech Apoznański; Urszula Zaleska-Dorobisz; Jerzy Czernik


Journal of Pediatric Surgery | 2008

Laparoscopic splenectomy in childrena multicenter experience

Maciej Murawski; Dariusz Patkowski; Wojciech Korlacki; Piotr Czauderna; Mariusz Sroka; Wojciech Makarewicz; Jerzy Czernik; Józef Dzielicki


Neurourology and Urodynamics | 2006

Assessing bladder capacity in children: Is it feasible at all?

Rafał Chrzan; Jerzy Czernik; Wojciech Apoznański; Maciej Bagłaj; Dariusz Patkowski

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Maciej Bagłaj

Wrocław Medical University

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Wojciech Jaworski

Wrocław Medical University

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Józef Dzielicki

Medical University of Silesia

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Wojciech Korlacki

Medical University of Silesia

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