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Dive into the research topics where Jess Taylor is active.

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Featured researches published by Jess Taylor.


Tetrahedron Letters | 2002

Parallel synthesis of 1,2,4-trisubstituted imidazoles via N-alkyl-N-(β-keto)amides using a carbazate linker

James M. Cobb; Neil Grimster; Nawaz Mohammed Khan; Justine Y.Q. Lai; Helen Payne; Lloyd J. Payne; Tony Raynham; Jess Taylor

Abstract The synthesis of 1,2,4-trisubstituted imidazoles was demonstrated via the solid phase synthesis of N -alkyl- N -(β-keto)amides using a carbazate linker. The approach enabled the assembly of a diverse number of N -alkyl- N -(β-keto)amide intermediates in good yield and purity. Subsequent cyclisation in solution using NH 4 OAc led to the preparation of 1400 1,2,4-trisubstituted imidazoles.


Archive | 2007

Triazole derivatives as kinase inhibitors

Francis X. Wilson; Nigel Ramsden; Kathryn Bell; Andrew Cansfield; Svenja Burckhardt; Jess Taylor; Mihiro Sunose; David Middlemiss


Archive | 2008

Amino triazoles as pi3k inhibitors

Nigel Ramsden; Kathryn Bell; Andrew Cansfield; Jess Taylor; Mihiro Sunose; David Middlemiss; Gitte Neubauer


Archive | 2005

biphenyl) carboxylic acids and derivatives thereof

Francis X. Wilson; Alison Reid; Valerie Reader; Richard John Harrison; Mihiro Sunose; Remedios Hernandez-Perni; Jeremy Major; Cyrille Boussard; Kathryn Smelt; Jess Taylor; Adeline Leformal; Andrew Cansfield; Svenja Burckhardt


Archive | 2009

2-aminoimidazo[1,2-b]pyridazine derivatives as pi3k inhibitors

Nigel Ramsden; Kathryn Bell; Andrew Cansfield; Jess Taylor; Mihiro Sunose; David Middlemiss


Medicinal Research Reviews | 2005

Preparation of kinase-biased compounds in the search for lead inhibitors of kinase targets†

Justine Y.Q. Lai; Steven P. Langston; Ruth Adams; Rebekah E. Beevers; Richard J. Boyce; Svenja Burckhardt; James M. Cobb; Yvonne Ferguson; Eva Figueroa; Neil Grimster; Andrew H. Henry; Nawaz Mohammed Khan; Kerry Jenkins; Mark W. Jones; Robert Judkins; Jeremy Major; Abid Masood; James Nally; Helen Payne; Lloyd J. Payne; Gilles Raphy; Tony Raynham; John C. Reader; Valerie Reader; Alison Reid; Parminder Ruprah; Michael Shaw; Hannah Fiona Sore; Matthew Stirling; Adam Talbot


Archive | 2006

(Benzyloxy-biphenyl) acetic acids and derivatives thereof and their use in therapy

Francis X. Wilson; Alison Reid; Valerie Reader; Richard John Harrison; Mihiro Sunose; Remedios Hernandez-Perni; Jeremy Major; Cyrille Boussard; Kathryn Smelt; Jess Taylor; Adeline Leformal; Andrew Cansfield; Svenja Burckhardt


Archive | 2010

Urea triazololo [1, 5-a] pyridine derivatives as pi3k inhibitors

Nigel Ramsden; Kathryn Bell; Jess Taylor; Mihiro Sunose; David Middlemiss; Katie Ellard


Archive | 2009

7-substituted amino triazoles as pi3k inhibitors

Nigel Ramsden; Kathryn Bell; Andrew Cansfield; Jess Taylor; Mihiro Sunose; David Middlemiss; Katie Ellard


Archive | 2009

7-pyridinyl- or phenyl- substituted triazolo [1, 5 -a] pyridines as pi3k inhibitors

Nigel Ramsden; Kathryn Bell; Jess Taylor; Mihiro Sunose; David Middlemiss; Katie Ellard

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Andrew Cansfield

University of Hertfordshire

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Svenja Burckhardt

Millennium Pharmaceuticals

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Alison Reid

Millennium Pharmaceuticals

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Valerie Reader

Millennium Pharmaceuticals

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Jeremy Major

Millennium Pharmaceuticals

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