Jesús Talavera López

Alterations in the large peripheral circulation in dogs with heart failure.

The femoral artery is responsible for perfusion of a large muscular region that can be involved in the exercise intolerance shown by dogs with spontaneous heart failure. The objective of the present study was to evaluate blood flow in the femoral artery by transcutaneous duplex Doppler ultrasonography (TDU) in 50 healthy dogs and 50 dogs with spontaneous heart failure. The group of dogs with heart disease was divided according to the functional class of the heart failure. The TDU measurements were: peak systolic velocity (PSV), early retrograde (EDV) and end diastolic velocities (EnDV), mean velocity (MV), pulsatility index (PI), resistivity index (RI) and femoral flow volume (FFV). In healthy dogs, PSV and FFV were significantly higher than in dogs with heart disease. FFV was reduced mainly in patients with moderate and severe heart failure. TDU allowed for non-invasive detection and quantification of pathological alterations in peripheral hemodynamics.

Nasopharyngeal stenosis secondary to soft palate dysgenesis in a cat.

This report is the first description of soft palate dysgenesis inducing nasopharyngeal stenosis in a cat. The symptomatology included continuous stertorous respiration and changes in phonation. Open-mouth breathing, seromucous nasal discharge and sneezing were intermittently present. On physical examination the cat showed a respiratory pattern characteristic of upper airway disease, with stridor, increased inspiratory effort and severe bilateral obstruction of nasal passages to the airflow. Pharyngo-laryngoscopic evaluation showed an abnormal conformation of the soft palate that appeared attached to the caudal and lateral pharyngeal wall and stretched the whole length of the pharynx. A strip of soft tissue emanated from the caudal part of the hard palate to the right aspect of the base of the tongue. Caudal to this strip of tissue, the intrapharyngeal opening was stenosed, therefore preventing normal airflow. Surgical reconstruction was not recommended. The cat was clinically stable with mild respiratory symptoms 17 months after the diagnosis.

Effects of a combination of acepromazine maleate and butorphanol tartrate on conventional and two-dimensional speckle tracking echocardiography in healthy dogs

OBJECTIVE To determine effects of a combination of acepromazine maleate and butorphanol tartrate on conventional echocardiographic variables and on strain values obtained by use of 2-D speckle tracking echocardiography (STE) in healthy dogs. ANIMALS 18 healthy medium- and large-size adult dogs. PROCEDURES Transthoracic echocardiographic examination (2-D, M-mode, color flow, spectral Doppler, and tissue Doppler ultrasonography) and high-definition oscillometric blood pressure measurement were performed before and after dogs were sedated by IM administration of a combination of acepromazine (0.02 mg/kg) and butorphanol (0.2 mg/kg). Adequacy of sedation for echocardiographic examination was evaluated. Circumferential and longitudinal global and segmental strains of the left ventricle (LV) were obtained with 2-D STE by use of right parasternal short-axis and left parasternal apical views. Values before and after sedation were compared. RESULTS The sedation combination provided adequate immobilization to facilitate echocardiographic examination. Heart rate and mean and diastolic blood pressures decreased significantly after dogs were sedated. A few conventional echocardiographic variables differed significantly from baseline values after sedation, including decreased end-diastolic LV volume index, peak velocity of late diastolic transmitral flow, and late diastolic septal mitral and tricuspid annulus velocities, increased ejection time, and increased mitral ratio of peak early to late diastolic filling velocity; global strain values were not affected, but 1 segmental (apical lateral) strain value decreased significantly. CONCLUSIONS AND CLINICAL RELEVANCE Results indicated that acepromazine and butorphanol at the doses used in this study provided sedation adequate to facilitate echocardiography, with only mild influences on conventional and 2-D STE variables.

Evaluation of the right parasternal four-chamber view for the assessment of left ventricular longitudinal strain and strain rate by two-dimensional speckle tracking echocardiography in dogs

Two-dimensional (2-D) speckle tracking echocardiography (STE) is a relatively new imaging technique, introduced in veterinary medicine to aid the assessment of left ventricular (LV) myocardial function. Among other indices, LV longitudinal strain and strain rate (SR) can be measured with this modality, and in dogs they are usually obtained from the left apical four-chamber (LAp4Ch) view. However, in this species, a good quality right parasternal four-chamber (RP4Ch) view can generally be attained, and the aim of this study was therefore to determine its feasibility and reliability for longitudinal strain and SR assessment, and to establish whether the two projections can be used interchangeably. Fifty-one healthy dogs and twenty-five dogs with various cardiac diseases were examined. Longitudinal global and segmental strains and global SR of the LV were obtained with 2-D STE by use of RP4Ch and LAp4Ch views. Intra-observer (within-day and between-day) and inter-observer variabilities were established, and strain and SR values obtained from the two views were compared. The RP4Ch view demonstrated to be feasible for the assessment of longitudinal strain and SR by use of 2-D STE in healthy and diseased dogs. However, out of sector motion of the apical segments could occur and induce tracking errors. The deformation parameters obtained from this view and the LAp4Ch view were often significantly different, and therefore they should not be used interchangeably. Further, the software employed in the present study performed better global than segmental strain analysis for both views.

Effects of sedation with acepromazine maleate and buprenorphine hydrochloride on femoral artery blood flow in healthy dogs

The purpose of this study was to qualify and quantify the femoral artery blood flow by duplex Doppler ultrasonography (DDU) in healthy dogs, before and after the administration of a combination of acepromazine maleate and buprenorphine hydrochloride (ACP-BPN). Seven healthy adult mongrel dogs and three adult beagles were used. Heart rate, arterial blood pressure and measurement of femoral artery blood flow by DDU were also recorded. The DDU measurements were: femoral artery diameter (FAD), peak systolic velocity (PSV), early retrograde (EDV) and end diastolic velocities (EnDV), mean velocity (BMV), pulsatility index (PI), flow velocity integral (FVI) and femoral blood flow (FBF). After 30 min, combination ACP-BPN was administered intramuscularly, and all the measurements were recorded again. The ACP-BPN protocol induced a significant decrease in systolic, mean, and diastolic arterial blood pressure, and heart rate. A significant increase in peak systolic velocity and integral flow velocity integral of the femoral blood were obtained. The Doppler spectra of the blood flow in the femoral artery revealed a spectral dispersion pattern after ACP-BPN administration in all the dogs. These results demonstrate that despite quantitative and qualitative changes, the overall femoral blood flow (FBF) is not significantly modified.