Jill Panosian

IMPACT OF TEMPORAL RESOLUTION OF THREE-DIMENSIONAL ECHOCARDIOGRAPHY ON LEFT VENTRICULAR STRAIN EVALUATION: AN EXPERIMENTAL STUDY

Methods: Five freshly harvested porcine heart phantom models were passively driven by a calibrated pump at stroke volumes (SVs) 30-70 ml. Full-volume data was acquired before and after a simulated myocardial infarction (MI) at two different temporal resolutions (FR = 18 volumes per second [vps] and FR = 30 vps) on a Toshiba Artida 4D Ultrasound System. LS and CS values were calculated from the 4D echo data then evaluated against sonomicrometry.

OP15.04: Data from a new matrix transducer to assess normal fetal hearts quantitatively

Objectives: STIC volumetry has been used to quantify cardiac chamber volumes, but this quantification has not been thoroughly validated. In an in vitro validation study, using a new matrix transducer and advanced quantification software, we could recently show the accuracy of ventricular volume determination small hearts (volumes from 1–5 ml). We applied this analysis of matrix transducer data to normal fetal hearts. Methods: Volume sequences from 80 normal fetuses were obtained as part of routine midand third trimester examinations using a new matrix probe (X6-1 matrix probe and iU22, both Philips). The volumes were later analyzed offline (using QLab GI-3DQ, Philips) for LV and RV end diastolic and end-systolic volumes. Results: Data of the first 20 fetuses have so far been analyzed. There is a an increase of RV and LV chamber volumes from 0.5 ml (enddiastole) and 0.2 ml (end-systole) for RV, 0.7 ml and 0.2 ml for LV at 19–25 weeks to 4.2 ml/1.7 ml for RV and 3.2 ml/1.4 ml for LV at 35–36 weeks’ gestation. Conclusions: Using a matrix transducer and advanced volume analysis software fetal cardiac chamber volumes can be analyzed in a system that has been validated in vitro. The high resolution of the matrix probe promises accuracy beyond the currently used STIC approach. Next, both techniques should be compared in the same patients.

OP15.03: Volume and mass calculation of small hearts using matrix transducer data: in vitro validation

B. Adriaanse1, C. Tromp1, J. Simpson2, T. Van Mieghem3, J. Kist4, J. Kuik5, D. Oepkes4, J. Van Vugt6, M. Haak4 1Department of Obstetrics and Gynecology, VU University Medical Center, Amsterdam, Netherlands; 2Department of Congenital Heart Disease, Fetal Cardiology Unit, Evelina Children’s Hospital, London, United Kingdom; 3Department of Obstetrics and Gynecology, Fetal Medicine Unit, University Hospitals Leuven, Leuven, Belgium; 4Department of Obstetrics and Gynecology, Leiden University Medical Center, Leiden, Netherlands; 5Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, Netherlands; 6Department of Obstetrics and Gynecology, Radboud University Nijmegen Medical Center, Nijmegen, Netherlands