Jinhong Guo

A Dual-Loop Antenna Design for Hepta-Band WWAN/LTE Metal-Rimmed Smartphone Applications

A simple direct-fed dual-loop antenna capable of providing hepta-band WWAN/LTE operation under surroundings of an unbroken metal rim in smartphone applications is proposed. The greatest highlight of this proposed antenna is that it provides a simple and effective multiband antenna solution for an unbroken metal-rimmed smartphone. The unbroken metal rim with 5 mm in height embraces the system circuit board of 130 × 70 mm2. Two no-ground portions of 10 × 70 mm2 and 5 × 70 mm2 are set on the top and bottom edge of the system circuit board, respectively. In-between the two separate no-ground portions, there is a system ground of 115 × 70 mm2 connected with the unbroken metal rim via a small grounded patch which divides the unbroken metal rim into two strips. Finally, a dual-loop antenna is formed by combining the inner system ground and two strips. This proposed dual-loop antenna is capable of covering GSM850/900/DCS/PCS/UMTS2100/LTE 2300/2500 operating bands. Detailed design considerations of the proposed antenna are described and both experimental and simulation results are also presented and discussed.

Small-Size Coupled-Fed Antenna With Two Printed Distributed Inductors for Seven-Band WWAN/LTE Mobile Handset

A compact small-size coupled-fed antenna with two symmetrical printed meandered inductive strips as two distributed inductors for seven-band operation covering the GSM850/900/1800//1900/UMTS2100/LTE2300/2500 bands in the internal mobile handset application is proposed. Wideband operation is achieved by incorporating a feeding strip and two radiating strips of different lengths, which are both disposed on the no-ground board space of the proposed antenna. The desired lower bands of GSM850/900 operation can be achieved by the two radiating strips of different lengths, which provide a quarter-wavelength dual-resonance mode at 810 and 962 MHz. While the feeding strip can provide a quarter-wavelength resonant mode at around 1.78 GHz, and other resonant modes at 2.45 GHz are contributed by the higher-order resonant modes of the two radiating strips, covering the desired upper bands of DCS1800/PCS1900/UMTS2100/LTE2300/2500 operation. In addition, the proposed antenna only occupies a planar size of 15×30 mm2 and is easily printed on one surface of a FR4 substrate, which makes it suitable for practical mobile applications. Detailed considerations of the design and main parameters are studied in this communication and the proposed antenna is successfully simulated, fabricated, and measured.

Printed wideband antenna with chip-capacitor-loaded inductive strip for lte/Gsm/Umts wwan wireless usb dongle applications

This paper proposes a planar printed wideband an- tenna for eight-band LTE/GSM/UMTS WWAN wireless USB don- gle applications. An inductive shorted strip with a chip capaci- tor loaded is employed in order to improve the characteristics of small-size terminal antennas which usually have a narrow band over the LTE700/GSM850/900 (698{960MHz) operation. While the desired upper band is mainly realized by the rectangular radi- ating patch, covering DCS1800/PCS1900/UMTS2100/LTE2300/2500 (1710{2690MHz) band. Easily printed on a 0.8-mm thick FR4 di- electric substrate of size 20£70mm 2 , the proposed antenna structure occupies a compact size of 20£19mm 2 . Then the proposed design can be attached to laptop computer by the USB interface. Good radiation e-ciency and antenna gain for frequencies over the desired operating bands is obtained. Detailed design considerations of the proposed an- tenna are described, and both experimental and simulation results are also presented and discussed.

A contact-imaging based microfluidic cytometer with machine-learning for single-frame super-resolution processing.

Lensless microfluidic imaging with super-resolution processing has become a promising solution to miniaturize the conventional flow cytometer for point-of-care applications. The previous multi-frame super-resolution processing system can improve resolution but has limited cell flow rate and hence low throughput when capturing multiple subpixel-shifted cell images. This paper introduces a single-frame super-resolution processing with on-line machine-learning for contact images of cells. A corresponding contact-imaging based microfluidic cytometer prototype is demonstrated for cell recognition and counting. Compared with commercial flow cytometer, less than 8% error is observed for absolute number of microbeads; and 0.10 coefficient of variation is observed for cell-ratio of mixed RBC and HepG2 cells in solution.

Uric Acid Monitoring with a Smartphone as the Electrochemical Analyzer

We report the worlds first medical smartphone as an electrochemical analyzer, which is incorporated with an enzymatic test strip for rapid characterization of UA (uric acid) in peripheral whole blood. A disposable electrochemical uric acid test strip was connected to the electrochemical module integrated with the smartphone through a specific interface, a slot around the edge of smartphone. A 3 μL human finger whole blood drop is applied on the strip for UA evaluation and compared to the clinical biochemical analyzer with satisfactory agreement. The measured data was saved and uploaded into a personal health management center through the mobile Internet.

Simultaneous monitoring of glucose and uric acid on a single test strip with dual channels

The conventional test strip has usually only one electrochemical reaction channel, which requires two times figure punctures for the self-management of patients suffering from both diabetes and gout. Considering the large number of such patients and for the sake of reducing their pains, we report an enzymatic test strip which can simultaneously monitor glucose and uric acid (UA) with only one fingertip blood droplet. The proposed test strip is composed of dual channels. The glucose in blood is detected in the 1st channel above on the substrate and the UA is characterized in the 2nd channel located at the bottom of the substrate. The proposed design intensively matches the requirement of those patients simultaneously suffering from diabetes and gout. We carried out comparative investigations on the proposed test strip and clinical biochemical analyser, which indicates a good agreement and proved the reliability and accuracy of the proposed test strip, as promising solution for the fast growth of family health management market.

3D numerical simulation of a Coulter counter array with analysis of electrokinetic forces

Coulter counters have played an important role in biological cell assays since their introduction decades ago. Several types of high throughput micro‐Coulter counters based on lab‐on‐chip devices have been commercialized recently. In this paper, we propose a highly integrated micro‐Coulter counter array working under low DC voltage. The real‐time electrical current change, including the pulse amplitude and width, of the micro‐Coulter counter with novel structure is systematically investigated numerically. The major types of forces exerted on the particle in the micro‐Coulter counter, including hydrodynamic force and electrokinetic force are quantitatively analyzed. The simulation in this study shows the pulse profile, such as width and amplitude, is affected by both particle size and the flow condition. The special cases of multiple particle aggregation and cross‐talk between neighboring channels are also considered for their effects on the electric current pulses. This simulation provides critical insight and guidance for developing next new generations of micro‐Coulter counter.

PDMS-film coated on PCB for AC impedance sensing of biological cells

Microfluidic impedance sensor has been introduced as a cost effective platform in biological cell sensing and counting since several decades ago. Conventional microfluidic impedance sensor usually requires the patterned gold electrodes directly in contact with the carrying buffer to measure the electrical current change due to the blockage of cells. However, patterning metal electrode probes on the silicon or glass substrate is a non-trivial task, which increases the fabrication cost of the impedance sensor. In this paper, we demonstrate an alternating current (AC) impedance based microfluidic cytometer built on a printed circuit board (PCB) coated with polydimethylsiloxane (PDMS) thin film. In addition, circulating tumor cells (Hela cells) are used to successfully demonstrate the feasibility of the microfluidic AC impedance sensor in tumor cell detection. The electrodes pre-deposited PCB costs less than US

On-Demand Lensless Single Cell Imaging Activated by Differential Resistive Pulse Sensing

2.00 and is widely available in the market. This device has a good potential for point-of-care diagnosis in resource-poor settings.

Design of a Fluidic Circuit-Based Microcytometer for Circulating Tumor Cell Detection and Enumeration

We present an on-demand single cell imaging technique activated by differential resistive pulse sensing in a portable system integrating a microfluidic differential coulter counter and a lensless complementary metal-oxide-semiconductor (CMOS) imaging sensor. Dual parametric single cell analysis and on-demand single cell imaging have been demonstrated by microbeads of different sizes and a cell mixture including red blood cells (RBCs) and tumor cell line HepG2 cells. The on-demand imaging capability could avoid generating useless images without cells and enable selective imaging of single cells within a specific size range.