Jiri Dusek

PS 02-66 AMBULATORY BLOOD PRESSURE MONITORING ANALYSED FROM SEVEN DAY/ 24 HOUR RECORD

Objective: From the database of 348 patients with essential hypertension, we analyzed the seven day mean blood pressure from seven day/ 24 hour ambulatory monitoring and we studied the relationship between age and circadian blood pressure variation. Design and Method: Three hundred and forty-eight patients in the age from 20 to 82 years, were ambulatory monitored for seven-day/24 hour. Medical instruments (A&D, Japan) were used for ambulatory blood pressure monitoring (oscillation method, 30-minute interval between measurements). We calculated mean values of seven day/24 hour monitoring for systolic and diastolic blood pressure (M) and mean value of amplitude ( of the curve (double amplitude corresponds to the night-day difference) were evaluated double amplitude (2A). Results: Mean values of seven day/24hour systolic and diastolic blood pressure of M (±SD) for the whole group were: SBP was 125 ± 8mmHg, DBP was 76 ± 6 mmHg, HR was 71 ± 6 bpm; of 2A: SBP – 21 ± 7, DBP – 15 ± 5 mmHg, HR – 15 ± 6 bpm. The linear relationship between M of SBP and age (r = 0.34, p< 0.001) and DBP and age (r = 0.39, p<0.001) was found (difference between age 20 and 77 years: SBP – 16 mmHg, DBP-12 mmHg). 2A of SBP and DBP was increasing with age up to 35 years, then the curve remained relatively flat up to 55 years (maximum at 45 years) and then decreased again (difference between 45 and 77 years: SBP was 13mmHg, DBPwas12 mmHg). Heart rate values of M and 2A were age-independent. Conclusions: Seven day /24 hour blood pressure monitoring showed that mean values of seven day/24 hour blood pressure of SBP were increasing with age up to 75 years, night-day difference of SBP and DBP reached the maximum value at 45 years and then decreased.

887 Seven day blood pressure monitoring in patients after myocardial infarction

Objective: The aim of the study was to compare 24-hour course of blood pressure immediately after the cardiovascular exercise training with the values from the following day when the patients after myocardial infarction did not exercise. Method: The group being monitored consisted of 41 patients after myocardial infarction of the age 63 ± 6.3 years and ejection fraction 43 ± 12.3 %. In the course of cardiac rehabilitation (aerobic and resistance training, lasted 60 minutes), the patients were subjected to 7-day ambulatory blood pressure monitoring (AD TM2421 Japan). During 7-day blood pressure monitoring their pharmacotherapy was not interrupted and consisted of ACE inhibitors, betablockers and statins. Results: The mean values of 24-h blood pressure profile (systolic ad diastolic) did not differ between the day with exercises and the day without exercise (120 ± 9 versus 120 ± 8mmHg, 72 ± 8 versus 72 ± 8mmHg). Comparison of hour differences in systolic and diastolic blood pressure indicated that only in the first hour after the exercises training the systolic pressure is lower than in the check course (120+4 mmHg versus 125+3 mmHg, p<0.01). Also in the second hour after the exercises the value is lower, the difference, however, is not statistically significant any more. In the other hours both profiles were not different. We have found no differences in diastolic pressure. Conclusion: The analysis of 24-hour profile of systolic and diastolic blood pressure showed that the exercise training change systolic blood pressure only one hour immediately after the exercises.

S8-02 Home ambulatory blood pressure and heart rate monitoring in practice and for science: transyears and magnetoperiodism vs. photoperiodism

Home ambulatory blood pressure ang heart rate monitoring in practice and for science:transyears and megnetoperiodism vs. photoperiodism.