Jiwen Yuan

Nickel-Catalyzed Heck-Type Alkenylation of Secondary and Tertiary α-Carbonyl Alkyl Bromides†

the National Natural Science Foundation of China (20772093;20972118;20832003);the Fundamental Research Funds for the Central Universities, and the Program for New Century Excellent Talents in University and the Program for Changjiang Scholars and Innovative Research Team in University (IRT1030)

Transition-metal-free aerobic oxidation of primary alcohols to carboxylic acids

A transition-metal-free aerobic oxidation of primary alcohols to acids was achieved in the presence of a base. This transformation provides an effective protocol towards the synthesis of aryl, alkyl, heterocyclic and vinyl carboxylic acids.

Iodine-catalyzed C–H/S–H oxidative coupling: from 1,3-diketones and thiophenols to β-dicarbonyl thioethers

A novel method on iodine-catalyzed oxidative coupling between 1,3-diketones and thiophenols to form β-dicarbonyl thioethers was developed. The C–S bond was supposed to be formed via a radical substitution pathway instead of the usual nucleophilic substitution one.

Oxidative cross S–H/S–H coupling: selective synthesis of unsymmetrical aryl tert-alkyl disulfanes

Selective oxidative coupling between aryl and tert-alkyl mercaptans was achieved using tert-butyl hydroperoxide (TBHP) as the oxidant and N-iodosuccinimide (NIS) as a catalyst. This protocol may provide an efficient process to synthesize unsymmetrical aryl tert-alkyl disulfanes.