Jl Barbur

Predicting chromatic sensitivity in normal trichromats and in subjects with congenital deficiency

Purpose Differences between M‐ and L‐class variant pigments arise largely because amino acid substitutions in M‐class pigments contribute less to the corresponding shifts in spectral responsivity. Other factors such as the relative numbers of L and M cones, their optical density and the midpoint between their spectral peaks can also contribute to the subject’s overall, red/green (RG) chromatic sensitivity. The purpose of this study was to examine how these differences affect chromatic sensitivity in normal trichromats and in subjects with deutan‐ and protan‐like deficiency.