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Dive into the research topics where Joachim Schorr is active.

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Featured researches published by Joachim Schorr.


Vaccine | 1998

Nucleic acid immunization protects dogs against challenge with virulent canine parvovirus.

Weiwen Jiang; Henry J. Baker; Larry J. Swango; Joachim Schorr; Melissa J. Self; Bruce F. Smith

Nucleic acid vaccines (NAVs) use expression vectors encoding one or more antigen genes to transfect host cells inducing both humoral and cellular immunity against the expressed antigen. NAV offers major advantages over conventional vaccines for the protection of humans and animals. This study shows that a plasmid DNA (pGT36VP1) encoding the full length VP1 region of canine parvovirus (CPV) induces immunity that protects dogs against challenge with virulent virus. Five dogs without anti-CPV antibodies were injected at 9 months of age with increasing doses of pGT36VP1 or saline. NAV vaccinated dogs showed an increase of serum IgG titer starting 1 week post-injection which peaked at week 2 and remained detectable for at least 14 weeks. A second dose of NAV resulted in an anamnestic response within 1 week. IgG titers peaked at week 3 and 4 after the second injection. All pGT36VP1 vaccinated dogs were protected against infection after virulent CPV challenge regardless of dose and the unvaccinated control dog was fully susceptible. This study demonstrated for the first time that a NAV can protect dogs against an infectious disease.


Archive | 1994

Chromatographic purification and separation process for mixtures of nucleic acids

Metin Colpan; Joachim Schorr; Ralf Herrmann; Petra Feuser


Archive | 1995

Process for the separation and purification of nucleic acids from biological sources

Metin Colpan; Joachim Schorr; Peter Moritz


Archive | 2002

Process for the depletion or removal of endotoxins

Metin Colpan; Peter Moritz; Joachim Schorr


Archive | 1995

Process for producing endotoxin-free or endotoxin-poor nucleic acids and/or oligonucleotides for gene therapy

Metin Colpan; Joachim Schorr; Peter Moritz


Archive | 2009

Isolation of nucleic acids on surfaces

Simone Gauch; Helge Bastian; Susanne Ullmann; Uwe Oelmüller; Martin Weber; Guido Fuhrmann; Joachim Schorr


Archive | 1999

Process for the preparation of endotoxin-free or endotoxin-depleted nucleic acids and/or oligonucleotides for gene therapy

Metin Colpan; Joachim Schorr; Peter Moritz


Archive | 1997

Nucleic acid vaccination for parvoviral infections

Metin Colpan; Joachim Schorr; Henry J. Baker; Bruce F. Smith


Archive | 1995

Endotoxin reduction or removal process

Metin Colpan; Peter Moritz; Joachim Schorr


Archive | 1995

Enhancement of the transfection efficiency of nucleic acids by using isopropanol in aqueous solutions

Metin Colpan; Joachim Schorr

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