Joerg R. Strub

All-ceramic partial coverage restorations—Midterm results of a 5-year prospective clinical splitmouth study

OBJECTIVES Midterm-evaluation of a 5-year prospective clinical splitmouth-investigation on survival rate and long-term behavior of all-ceramic partial coverage restorations (PCRs) on molars. Pressed ceramic and CAD/CAM fabricated PCRs were compared. METHODS 80 vital molars of 25 patients were restored with all-ceramic PCRs (40 IPS e.max Press*[IP] and 40 ProCAD*[PC]). IP-PCRs were heat pressed following the lost-wax method. PC-PCRs were fabricated with Cerec 3** and Cerec InLab** CAD/CAM system (**Sirona Dental Systems, Bensheim, Germany). All PCRs were adhesively luted with a light-polymerizing composite (Syntac*/Tetric*) (*Ivoclar Vivadent, Schaan, Liechtenstein). Clinical reevaluations were performed at baseline and 13, 25, and 36 months after insertion of the PCRs according to the modified United States Public Health Services (USPHS) criteria. Absolute failures were demonstrated by Kaplan-Meier survival rate. RESULTS After an observation time up to 3 years, survival rate of IP-PCRs was 100% and 97% for PC-PCRs due to one severe fracture. The PC-PCR had to be replaced after 9 months. Secondary caries and endodontic complications did not occur. Increased clinical service time resulted in significant decrease of marginal adaptation (p=0.031) and enhanced marginal discoloration (p<0.0001). Both PCR ceramic materials demonstrated significant deteriorations in color match (p<0.0001) and surface roughness (p<0.0001), IP-PCRs were significantly more affected (p< or =0.005). Regarding anatomic form IP-PCRs performed significantly better (p=0.0012). CONCLUSION Pressed ceramic and CAD/CAM fabricated partial coverage restorations exhibited a reliable treatment option to restore larger defects in posterior teeth. Marginal degradation of the resin cement and deterioration of the all-ceramic materials during clinical function determine the clinical long-term performance of partial coverage restorations.

The all-on-four treatment concept: a systematic review

PURPOSE The study aims to evaluate the all-on-four treatment concept with regard to survival rates (SRs) of oral implants, applied fixed dental prostheses (FDPs) and temporal changes in proximal bone levels. MATERIALS AND METHODS A systematic review of publications in English and German was performed using the electronic bibliographic database MEDLINE, the Cochrane Library, and Google. Hand searches were conducted of the bibliographies of related journals and systematic reviews. The authors performed evaluations of articles independently, as well as data extraction and quality assessment. Data were submitted the weighted least-squared analysis. RESULTS Thirteen (487 initially identified) papers met inclusion criteria. A number of 4,804 implants were initially placed, of which 74 failed, with a majority of failures (74%) within the first 12 months. A total of 1,201 prostheses were incorporated within 48 hours after the surgery. The major prosthetic complication was the fracture of the all-acrylic FDP. The mean cumulative SR/SR ± (standard deviation) (36 months) of implants and prostheses were 99.0 ± 1.0% and 99.9 ± 0.3%, respectively. The averaged bone loss was 1.3 ± 0.4 mm (36 months). No statistically significant differences were found in outcome measures, when comparing maxillary versus mandibular arches and axially versus tilted placed implants. CONCLUSION The available data provide promising short-term results for the all-on-four treatment approach; however, current evidence is limited by the quality of available studies and the paucity of data on long-term clinical outcomes of 5 years or greater. In terms of an evidence-based dentistry, the authors recommend further studies designed as randomized controlled clinical trials and reported according to the CONSORT statement.

Monolithic and bi-layer CAD/CAM lithium–disilicate versus metal–ceramic fixed dental prostheses: Comparison of fracture loads and failure modes after fatigue

ObjectivesThe authors analyzed the effect of fatigue on the survival rate and fracture load of monolithic and bi-layer CAD/CAM lithium–disilicate posterior three-unit fixed dental prostheses (FDPs) in comparison to the metal–ceramic gold standard.Materials and methodsThe authors divided 96 human premolars and molars into three equal groups. Lithium–disilicate ceramic (IPS-e.max-CAD) was milled with the CEREC-3-system in full-anatomic FDP dimensions (monolithic: M-LiCAD) or as framework (Bi-layer: BL-LiCAD) with subsequent hand-layer veneering. Metal–ceramic FDPs (MC) served as control. Single-load-to-failure tests were performed before and after mouth-motion fatigue.ResultsNo fracture failures occurred during fatigue. Median fracture loads in [N], before and after fatigue were, respectively, as follows: M-LiCAD, 1,298/1,900; BL-LiCAD, 817/699; MC, 1,966/1,818. M-LiCAD and MC FPDs revealed comparable fracture loads and were both significantly higher than BL-LiCAD. M-LiCAD and BL-LiCAD both failed from core/veneer bulk fracture within the connector area. MC failures were limited to ceramic veneer fractures exposing the metal core. Fatigue had no significant effect on any group.ConclusionsPosterior monolithic CAD/CAM fabricated lithium–disilicate FPDs were shown to be fracture resistant with failure load results comparable to the metal–ceramic gold standard. Clinical investigations are needed to confirm these promising laboratory results.Clinical relevanceMonolithic CAD/CAM fabricated lithium–disilicate FDPs appeared to be a reliable treatment alternative for the posterior load-bearing area, whereas FDPs in bi-layer configuration were susceptible to low load fracture failure.

Marginal and internal fit of heat pressed versus CAD/CAM fabricated all-ceramic onlays after exposure to thermo-mechanical fatigue

OBJECTIVES The aim of the study was to evaluate the marginal and internal fit of heat-pressed and CAD/CAM fabricated all-ceramic onlays before and after luting as well as after thermo-mechanical fatigue. MATERIALS AND METHODS Seventy-two caries-free, extracted human mandibular molars were randomly divided into three groups (n=24/group). All teeth received an onlay preparation with a mesio-occlusal-distal inlay cavity and an occlusal reduction of all cusps. Teeth were restored with heat-pressed IPS-e.max-Press* (IP, *Ivoclar-Vivadent) and Vita-PM9 (VP, Vita-Zahnfabrik) as well as CAD/CAM fabricated IPS-e.max-CAD* (IC, Cerec 3D/InLab/Sirona) all-ceramic materials. After cementation with a dual-polymerising resin cement (VariolinkII*), all restorations were subjected to mouth-motion fatigue (98 N, 1.2 million cycles; 5°C/55°C). Marginal fit discrepancies were examined on epoxy replicas before and after luting as well as after fatigue at 200× magnification. Internal fit was evaluated by multiple sectioning technique. For the statistical analysis, a linear model was fitted with accounting for repeated measurements. RESULTS Adhesive cementation of onlays resulted in significantly increased marginal gap values in all groups, whereas thermo-mechanical fatigue had no effect. Marginal gap values of all test groups were equal after fatigue exposure. Internal discrepancies of CAD/CAM fabricated restorations were significantly higher than both press manufactured onlays. CONCLUSIONS Mean marginal gap values of the investigated onlays before and after luting as well as after fatigue were within the clinically acceptable range. Marginal fit was not affected by the investigated heat-press versus CAD/CAM fabrication technique. Press fabrication resulted in a superior internal fit of onlays as compared to the CAD/CAM technique. CLINICAL RELEVANCE Clinical requirements of 100 μm for marginal fit were fulfilled by the heat-press as well as by the CAD/CAM fabricated all-ceramic onlays. Superior internal fit was observed with the heat-press manufacturing method. The impact of present findings on the clinical long-term behaviour of differently fabricated all-ceramic onlays warrants further investigation.

Effect of mouth-motion fatigue and thermal cycling on the marginal accuracy of partial coverage restorations made of various dental materials.

OBJECTIVES To investigate the influence of mouth-motion fatigue on marginal-accuracy of partial-coverage-restorations-(PCRs) of various dental materials. METHODS Eighty molars were prepared equally and divided into five groups (n=16). PCRs were fabricated of following dental materials: Group-GO=Gold-Pontor-MPF(double dagger), Group-TA=Targis*, Group-EX=IPS-e.max-Press*, Group-EM=IPS-Empress*, Group-PC=ProCAD*/Cerec 3(dagger) ((double dagger)Metalor/*Ivoclar-Vivadent/(dagger)Sirona-Dental-System). Gold-PCRs were cemented conventionally. Residual 64 PCRs were adhesively luted and subjected to masticatory loading (1.2million-cycles, 1.6Hz, 49N) and thermal cycling (5 degrees C/55 degrees C, 60s, dwell-time, 5500cycles). Discrepancies in marginal-accuracy were examined on epoxy replicas (200 x magnification). Statistical analysis was performed by unpaired and paired t-tests (alpha=0.05). RESULTS After cementing, marginal-accuracy (geometrical mean)[95% confidence limits] was recorded: GO-47[43-51]microm, TA-42[38-45]microm, EX-60[52-67]microm, EM-52[45-60]microm and PC-75[59-94]microm. No significant differences were found between groups GO, TA and EM. Values of Group-EX were significantly higher compared to Group-TA (p=0.04). Group-PC demonstrated significantly decreased marginal-accuracy towards groups GO (p=0.03) and TA (p=0.02). Except for Group-GO (p=0.01), no significant changes in marginal-accuracy were observed after mouth-motion fatigue and thermal cycling (GO-42[38-45]microm, TA-42[38-47]microm, EX-56[49-65]microm, EM-54[46-64]microm and PC-71[59-84]microm). However, Group-GO and Group-EM showed significant deviations in marginal-accuracy after aging (p=0.04). Marginal discrepancies of groups EX and EM were similar (p=1.0). Values of Group-PC were significantly higher when compared to groups GO (p=0.01) and TA (p=0.02). Buccal-lingual marginal discrepancies were significantly higher than mesial-distal in all groups and stages. SIGNIFICANCE Cast-gold-PCRs demonstrated superior marginal-accuracy, followed by indirect ceromer PCRs. All-ceramic PCRs showed in vitro clinical acceptable marginal widths, even though CAD/CAM fabrication slightly compromised marginal-accuracy. Since preparation margins were not exposed to occlusal loading directly, increased marginal discrepancies due to marginal chipping during mouth-motion fatigue were not experienced.

Influence of preparation design and ceramic thicknesses on fracture resistance and failure modes of premolar partial coverage restorations.

STATEMENT OF PROBLEM Preparation designs and ceramic thicknesses are key factors for the long-term success of minimally invasive premolar partial coverage restorations. However, only limited information is presently available on this topic. PURPOSE The purpose of this in vitro study was to evaluate the fracture resistance and failure modes of ceramic premolar partial coverage restorations with different preparation designs and ceramic thicknesses. MATERIAL AND METHODS Caries-free human premolars (n=144) were divided into 9 groups. Palatal onlay preparation comprised reduction of the palatal cusp by 2 mm (Palatal Onlay Standard), 1 mm (Palatal-Onlay-Thin), or 0.5 mm (Palatal Onlay Ultrathin). Complete-coverage onlay preparation additionally included the buccal cusp (Occlusal Onlay Standard; Occlusal Onlay Thin; Occlusal Onlay Ultrathin). Labial surface preparations with chamfer reductions of 0.8 mm (Complete-Veneer-Standard), 0.6 mm (Complete-Veneer-Thin), and 0.4 mm (Complete Veneer Ultrathin) were implemented for complete veneer restorations. Restorations were fabricated from a pressable lithium disilicate ceramic (IPS-e.max-Press) and cemented adhesively (Syntac-Classic/Variolink-II). All specimens were subjected to cyclic mechanical loading (F=49 N, 1.2 million cycles) and simultaneous thermocycling (5°C to 55°C) in a mouth-motion simulator. After fatigue, restorations were exposed to single-load-to-failure. Two-way ANOVA was used to identify statistical differences. Pair-wise differences were calculated and P-values were adjusted by the Tukey-Kramer method (α=.05). RESULTS All specimens survived fatigue. Mean (SD) load to failure values (N) were as follows: 837 (320/Palatal-Onlay-Standard), 1055 (369/Palatal-Onlay-Thin), 1192 (342/Palatal-Onlay-Ultrathin), 963 (405/Occlusal-Onlay-Standard), 1108 (340/Occlusal-Onlay-Thin), 997 (331/Occlusal-Onlay-Ultrathin), 1361 (333/Complete-Veneer-Standard), 1087 (251/Complete-Veneer-Thin), 883 (311/Complete-Veneer-Ultrathin). Palatal-onlay restorations revealed a significantly higher fracture resistance with ultrathin thicknesses than with standard thicknesses (P=.015). Onlay restorations were not affected by thickness variations. Fracture loads of standard complete veneers were significantly higher than thin (P=.03) and ultrathin (P<.001) restorations. CONCLUSIONS In this in vitro study, the reduction of preparation depth to 1.00 and 0.5 mm did not impair fracture resistance of pressable lithium-disilicate ceramic onlay restorations but resulted in lower failure loads in complete veneer restorations on premolars.

Influence of Preparation and Wall Thickness on the Resistance to Fracture of Zirconia Implant Abutments

BACKGROUND Studies about the effect of grinding procedures as well as material thickness on the resistance of zirconia implant abutments are in short supply. PURPOSE This study evaluated the effect of wall thickness as well as preparation on the resistance of zirconia implant abutments. MATERIALS AND METHOD Sixty-four implants received titanium (group Ti) and zirconia abutments (groups Zr-8, Zr-18, and Zr-1). The abutments of group Zr-8 had a 0.8-mm wall thickness, whereas the wall thickness of group Zr-18 was reduced by preparation from 1 mm to 0.8 mm. The abutments of group Zr-1 had a wall thickness of 1 mm. Standardized maxillary central incisor metal crowns were cemented on all abutments. All specimens were then tested in a universal testing machine for their resistance to fracture before and after masticatory simulation (n = 8). RESULTS The median resistance to fracture values (N) before and after aging were, respectively: group Ti: 500-504; group Zr-8: 487-491; group Zr-18: 490-451; and group Zr-1: 519-480. No significant effects of group, aging, or combinations were found (p > .05). CONCLUSION All tested abutments have the potential to withstand physiologic occlusal forces in the anterior region (> 200 N). The applicability of the results to other implant systems should be verified.

Veneered anatomically designed zirconia FDPs resulting from digital intraoral scans: Preliminary results of a prospective clinical study.

OBJECTIVES The aim of this prospective clinical study was to evaluate the clinical performance of veneered anatomically designed zirconia fixed dental prostheses (FDPs) resulting from intraoral digital impressions. METHODS 24 patients requiring treatment were provided with all-ceramic FDPs. Intraoral scans (iTero) were performed and veneered anatomically designed CAD/CAM-zirconia FDPs (Zerion/VitaVM9) were fabricated. A feldspar veneering ceramic following a slow cooling firing protocol was applied. A self-curing resin based luting material was used for adhesive cementation. Clinical evaluations were performed at baseline and 6, 12, and 18 months recalls according to the modified USPHS-criteria. Intraoral digital surface scans (iTero) were performed at each recall examination and were digitally superimposed (Geomagic) to evaluate potential veneer cohesive fractures. Kaplan-Meier survival analysis comprised secondary caries, clinically unacceptable fractures, root canal treatment and debonding. Kaplan-Meier success rate included restorations with minimal crevices, tolerable color deviations and clinically acceptable fractures. Data were statistically analyzed. RESULTS The Kaplan-Meier survival rate and success rate of the FDPs were 100% and 91.7%, respectively. Clinically acceptable veneer cohesive fractures and crevices at the restoration margin were observed in two patients. These shallow veneer fractures were only detected by overlapping baseline and recall scans. Ceramic surface roughness increased significantly over time (p<0.0001). CONCLUSIONS Veneered zirconia FDPs fabricated from digital intraoral scans showed a favorable clinical performance over an observation period of 18 months. Anatomical zirconia core design and slow cooling firing protocol of the veneering ceramic reduced the incidence of chip fractures to a level that could not be detected clinically. CLINICAL SIGNIFICANCE The digital workflow on the basis of intraoral digital impressions resulted in clinically satisfying outcomes for veneered zirconia FDPs.

The Randomized Shortened Dental Arch Study: Tooth Loss Over 10 Years

PURPOSE This study aimed to compare the long-term outcomes of two different nonimplant treatments in the bilateral shortened dental arch (SDA). MATERIALS AND METHODS In a multicenter randomized controlled clinical trial, patients with complete molar loss in one arch were assigned to one of two different nonimplant treatments. In the partial removable dental prosthesis (PRDP) group, patients were provided with a distal-extension prosthesis retained with precision attachments. In the SDA group, patients were treated according to the SDA concept by preserving or restoring a premolar occlusion. RESULTS Of the 152 treated patients, 82 reached the 10-year examination independent of their dental or prosthetic status. In the intention-to-treat analysis, the survival rates for tooth loss at 10 years were 0.44 (95% confidence interval [CI]: 0.30 to 0.56) in the PRDP group and 0.52 (95% CI: 0.37 to 0.65) in the SDA group. For tooth loss in the study arch, the survival rates were 0.67 (95% CI: 0.52 to 0.78) in the PRDP group and 0.60 (95% CI: 0.45 to 0.73) in the SDA group. The number of teeth lost was higher than expected. In a multivariate analysis using a multiple Cox regression model, the covariates age (unit: 1 year, Hazard Ratio [HR]: 1.033, P = .03) and DMFT value (unit: 1 tooth, HR: 1.121, P = .03) were significant for time to first tooth loss in the study arch. CONCLUSION The results suggest an overestimation of the influence of the prosthetic management of the bilateral SDA. In treatment decisions, patient preferences should be considered with appropriate weight.