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Johanna D. Stoeckler

Butler Hospital

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Featured researches published by Johanna D. Stoeckler.

Nucleosides, Nucleotides & Nucleic Acids | 1989

Inhibition of Purine Nucleoside Phosphorylase by Phosphonoalkylpurines 1

Charles E. Nakamura; Shih-Hsi Chu; Johanna D. Stoeckler; Robert E. Parks

Abstract Optimum inhibition of human erythrocyte purine nucleoside phosphorylase by 9-(phosphonoalkyl)hypoxanthines required an alkyl chain of five carbons or longer. Appropriate modifications of either the base or phosphonate side chain resulted in increased inhibitory activity.

Biochemistry | 1997

Purine Nucleoside Phosphorylase. 2. Catalytic Mechanism

Mark D. Erion; Johanna D. Stoeckler; Wayne C. Guida; and Richard L. Walter; Steven E. Ealick

Biochemistry | 1980

Human erythrocytic purine nucleoside phosphorylase: reaction with sugar-modified nucleoside substrates.

Johanna D. Stoeckler; Carolyn Cambor; Robert E. Parks

Biochemistry | 1997

Purine nucleoside phosphorylase. 3. Reversal of purine base specificity by site-directed mutagenesis.

Johanna D. Stoeckler; Anne F. Poirot; Rose Marie Smith; Robert E. Parks; Steven E. Ealick; Kenji Takabayashi; Mark D. Erion

Biochemistry | 1975

Purine nucleoside phosphorylase. Microheterogeneity and comparison of kinetic behavior of the enzyme from several tissues and species

Kailash C. Agarwal; R. P. Agarwal; Johanna D. Stoeckler; R. E. Parks

Cancer Research | 1981

N,N-Dimethylformamide and Sodium Butyrate Modulation of the Activities of Purine-metabolizing Enzymes in Cultured Human Colon Carcinoma Cells

Daniel L. Dexter; Gerald W. Crabtree; Johanna D. Stoeckler; Todd M. Savarese; Lucy Y. Ghoda; Timothy Rogler-Brown; Robert E. Parks; Paul Calabresi

Cancer Research | 1986

Inhibitors of Purine Nucleoside Phosphorylase: Effects of 9-Deazapurine Ribonucleosides and Synthesis of 5′-Deoxy-5′-iodo-9-deazainosine

Johanna D. Stoeckler; Janice B. Ryden; R. E. Parks; Ming-Y. Chu; Mu-Ill Lim; Wu-Yun Ren; Robert S. Klein

Biochemistry | 1978

Purine nucleoside phosphorylase from human erythrocytes: Physicochemical properties of the crystalline enzyme

Johanna D. Stoeckler; R. P. Agarwal; Kailash C. Agarwal; Karl Schmid; R. E. Parks

Cancer Research | 1986

Changes in Nucleoside Transport of HL-60 Human Promyelocytic Cells during N,N-Dimethylformamide Induced Differentiation

Shih-Fong Chen; Jeffrey S. Cleaveland; Ann B. Hollmann; Michael C. Wiemann; Robert E. Parks; Johanna D. Stoeckler

Journal of Medicinal Chemistry | 1994

Adenosine deaminase inhibitors. Synthesis and biological evaluation of putative metabolites of (+)-erythro-9-(2S-hydroxy-3R-nonyl)adenine.

Chandra Vargeese; Mallela S. P. Sarma; Palle V.P. Pragnacharyulu; Elie Abushanab; Shih-Ying Li; Johanna D. Stoeckler

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Robert E. Parks

Brown University

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Elie Abushanab

University of Rhode Island

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Kailash C. Agarwal

Butler Hospital

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R. E. Parks

Butler Hospital

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Steven E. Ealick

University of Alabama at Birmingham

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Anne F. Poirot

Brown University

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Geraldine Harriman

University of Kansas

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R. P. Agarwal

Butler Hospital

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Mark D. Erion

Novartis

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Ann B. Hollmann

Brown University

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