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Dive into the research topics where Johannes Dodt is active.

Publication


Featured researches published by Johannes Dodt.


FEBS Letters | 1984

The complete amino acid sequence of hirudin, a thrombin specific inhibitor: Application of colour carboxymethylation

Johannes Dodt; Hans-Peter Müller; Ursula Seemüller; Jui-Yoa Chang

Color carboxymethylation of cysteine residues with a new chromophoric reagent dimethylaminoazobenzene iodoacetamide, was applied to the micro‐sequence analysis of hirudin, a thrombin specific inhibitor. Six cysteine residues of the reduced hirudin were detected as colored phenylthiohydantoin derivative and 3 tryptic peptides of hirudin (all containing cysteines) were isolated as colored peptide. The complete hirudin sequence, including 6 uncertain positions left in the previous report [Petersen T.E. (1976) in: Protides of the Biological Fluids; 23rd Colloquium, pp. 145, Pergamon Press, London] was established.


Biological chemistry Hoppe-Seyler | 1985

The complete covalent structure of hirudin. Localization of the disulfide bonds.

Johannes Dodt; Ursula Seemüller; Reinhard Maschler; Hans Fritz


Biological chemistry Hoppe-Seyler | 1986

Chemical synthesis and expression of a gene coding for hirudin, the thrombin-specific inhibitor from the leech Hirudo medicinalis.

Cornelia Bergmann; Johannes Dodt; Stefanie Köhler; Ernst Fink; Hans Günter Gassen


Biological chemistry Hoppe-Seyler | 1986

Isolation and Characterization of Hirudin Isoinhibitors and Sequence Analysis of Hirudin PA

Johannes Dodt; Werner Machleidt; Ursula Seemüller; Reinhard Maschler; Hans Fritz


Archive | 1985

Hirudin-PA and its derivatives, process for manufacturing these and the use of these substances

Johannes Dodt; Ursula Seemüller; Hans Fritz; Ernst Fink


Biological chemistry Hoppe-Seyler | 1987

Influence of Chain Shortening on the Inhibitor Properties of Hirudin and Eglin c

Johannes Dodt; Ursula Seemüller; Hans Fritz


Archive | 1986

Modified hirudines, process for their preparation and pharmaceutical agents containing them

Hans Fritz; Ursula Seemüller; Johannes Dodt; Ernst Fink


Archive | 1985

Hirudin-pa and derivatives thereof, process for the production a nd utilization thereof

Johannes Dodt; Ursula Seemüller; Hans Fritz; Ernst Fink


Archive | 1986

Hirudines modifiées, leur procédé de préparation et agents pharmaceutiques les contenant

Hans Fritz; Ursula Seemüller; Johannes Dodt; Ernst Fink


Archive | 1985

Hirudin pa and its derivatives, processes for their preparation and their use.

Johannes Dodt; Ursula Dr Seemueller; Hans Fritz; Ernst Fink

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Cornelia Bergmann

Darmstadt University of Applied Sciences

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Stefanie Köhler

Darmstadt University of Applied Sciences

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