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Dive into the research topics where John C. Clohisy is active.

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Featured researches published by John C. Clohisy.


Arthroscopy | 2012

Intra-Abdominal Fluid Extravasation During Hip Arthroscopy: A Survey of the MAHORN Group

Mininder S. Kocher; Jeremy S. Frank; Adam Y. Nasreddine; Marc R. Safran; Marc J. Philippon; Jon K. Sekiya; Bryan T. Kelly; J. W. Thomas Byrd; Carlos A. Guanche; Hal D. Martin; John C. Clohisy; Nick Mohtadi; Damian R. Griffin; Thomas G. Sampson; Michael Leunig; Christopher M. Larson; Victor M. Ilizaliturri; Joseph C. McCarthy; Peter G. Gambacorta

PURPOSEnThe purpose of this study was to survey experts in the field of hip arthroscopy from the Multicenter Arthroscopy of the Hip Outcomes Research Network (MAHORN) group to determine the frequency of symptomatic intra-abdominal fluid extravasation (IAFE) after arthroscopic hip procedures, identify potential risk factors, and develop preventative measures and treatment strategies in the event of symptomatic IAFE.nnnMETHODSnA survey was sent to all members of the MAHORN group. Surveys collected data on general hip arthroscopy settings, including pump pressure and frequency of different hip arthroscopies performed, as well as details on cases of symptomatic IAFE. Responses to the survey were documented and analyzed.nnnRESULTSnFifteen hip arthroscopists from the MAHORN group were surveyed. A total of 25,648 hip arthroscopies between 1984 and 2010 were reviewed. Arthroscopic procedures included capsulotomies, labral reattachment after acetabuloplasty, peripheral compartment arthroscopy, and osteoplasty of the femoral head-neck junction. Of the arthroscopists, 7 (47%) had 1 or more cases of IAFE (40 cases reported). The prevalence of IAFE in this study was 0.16% (40 of 25,650). Significant risk factors associated with IAFE were higher arthroscopic fluid pump pressure (P = .004) and concomitant iliopsoas tenotomy (P < .001). In all 40 cases, the condition was successfully treated without long-term sequelae. Treatment options included observation, intravenous furosemide, and Foley catheter placement, as well as 1 case of laparotomy.nnnCONCLUSIONSnSymptomatic IAFE after hip arthroscopy is a rare occurrence, with an approximate prevalence of 0.16%. Prevention of IAFE should include close intraoperative and postoperative monitoring of abdominal distention, core body temperature, and hemodynamic stability. Concomitant iliopsoas tenotomy and high pump pressures may be risk factors leading to symptomatic IAFE.nnnLEVEL OF EVIDENCEnLevel IV, therapeutic case series.


Clinical Orthopaedics and Related Research | 2013

Unstable SCFE: Review of Treatment Modalities and Prevalence of Osteonecrosis

Ira Zaltz; Geneva Baca; John C. Clohisy

BackgroundThe treatment of unstable slipped capital femoral epiphysis (SCFE) is rapidly evolving with the ability to correct epiphyseal alignment using the modified Dunn technique. Adopting a new treatment method depends on confirming that it achieves its goals, produces few, nonserious complications with no lasting sequelae, and improves the natural history of the disorder compared with known treatment methods. As such, the rates of osteonecrosis and complications after current treatments of unstable SCFE must be compared with those of newer surgical techniques.Questions/purposesWe therefore addressed the following questions: (1) What is the rate of osteonecrosis of the femoral head after treatment of unstable SCFE? (2) What treatment modalities have been used for unstable SCFE and (3) what are the reported complications?MethodsWe performed a systematic electronic literature search for the keywords unstable and slipped capital femoral epiphysis and identified 199 articles. Of these, 60 met our inclusion criteria. Fifteen articles were included for analysis.ResultsThe literature concerning the treatment and results of unstable SCFE is retrospective Level IV data that suggest an overall rate of osteonecrosis of 23.9%. Multiple treatment modalities were used for unstable SCFE treatment with varying, inconsistently recorded complications over the reporting period.ConclusionsWe found limited data concerning the rate of osteonecrosis and complications after treatment of unstable SCFE. Considering recent widespread interest in the modified Dunn procedure and the possibility of iatrogenic osteonecrosis, there is a need for prospective studies to identify complications and establish outcome based on standardized scores for established and emerging treatments of unstable SCFE.


Journal of Bone and Joint Surgery, American Volume | 2016

Hip Dysplasia in the Young Adult

Luca Gala; John C. Clohisy; Paul E. Beaulé

Hip dysplasia is a leading precursor of osteoarthritis and is seen in 20% to 40% of patients with osteoarthritis of the hip. An increase in mechanical stress on the cartilage matrix with failure of the acetabular labrum represents the major pathomechanism of degeneration. Because the prevalence of associated femoral deformities is high (>50%), the structural anatomy of the dysplastic hip must be assessed in multiple planes using radiographs and, if needed, advanced imaging modalities. Acetabular osteotomy (periacetabular and/or rotational) is the most commonly used procedure for the treatment of the majority of dysplastic hips in adults. Modern total hip replacement remains an excellent option for the more arthritic joints. Difficulties can arise from anatomical abnormalities and previous operations.


American Journal of Sports Medicine | 2018

Development of the HOOSglobal to Assess Patient-Reported Outcomes in Patients Undergoing Hip Preservation Procedures:

Cale A. Jacobs; Michael R. Peabody; Stephen T. Duncan; Ryan D. Muchow; Ryan M. Nunley; John C. Clohisy; Paul E. Beaulé; Young-Jo Kim; Michael B. Millis; David A. Podeszwa; Perry L. Schoenecker; Rafael J. Sierra; Ernest L. Sink; Daniel J. Sucato; Robert T. Trousdale; Ira Zaltz

Background: The creation of a single patient-reported outcome (PRO) platform validated across hip preservation, osteoarthritis (OA), and total hip arthroplasty (THA) populations may reduce barriers and streamline the routine collection of PROs in clinical practice. As such, the purpose of this study was to determine if augmenting the Hip disability and Osteoarthritis Outcome Score–Joint Replacement (HOOS, JR) with additional HOOS questions would result in a PRO platform that could be used across a wider spectrum of hip patient populations. Hypothesis: The HOOS, JR would demonstrate a notable ceiling effect, but by augmenting the HOOS, JR with additional HOOS questions, a responsive PRO platform could be created. Study Design: Cohort study (diagnosis); Level of evidence, 2. Methods: Using preoperative and postoperative HOOS responses from a sample of 304 patients undergoing periacetabular osteotomy (PAO), additional items were identified to augment the HOOS, JR. The psychometric properties of a newly created PRO tool (HOOSglobal) were then compared with the HOOS, JR and other PRO instruments developed for patients with hip OA and/or undergoing THA. Results: By augmenting the HOOS, JR with 2 additional questions, the HOOSglobal was more responsive than all other included PRO tools and had significantly fewer maximum postoperative scores than the HOOS, JR (P < .0001), HOOS–Physical Function Short form (P < .0001), Western Ontario and McMaster Universities Osteoarthritis Index (P = .02), University of California, Los Angeles activity scale (P = .0002), and modified Harris Hip Score (P = .04). The postoperative HOOSglobal score threshold associated with patients achieving the patient acceptable symptom state (PASS) was 62.5. Conclusion: The HOOSglobal is a valid and responsive PRO tool after PAO and may potentially provide the orthopaedic community with a PRO platform to be used across hip-related subspecialties. For patients undergoing PAO, a postoperative HOOSglobal score ≥62.5 was associated with patients achieving the PASS.


Journal of Orthopaedic Research | 2018

Canine hip dysplasia: A natural animal model for human developmental dysplasia of the hip: STUDY OF HUMAN HIP DYSPLASIA

Cecilia Pascual-Garrido; Farshid Guilak; M. Farooq Rai; Michael D. Harris; Mandi J. Lopez; Rory J. Todhunter; John C. Clohisy

Developmental dysplasia of the hip (DDH) in humans is a common condition that is associated with hip pain, functional limitations, and secondary osteoarthritis (OA). Surgical treatment of DDH has improved in the last decade, allowing excellent outcomes at short‐ and mid‐term follow‐up. Still, the etiology, mechanobiology, and pathology underlying this disease are not well understood. A pre‐clinical animal model of DDH could help advance the field with a deeper understanding of specific pathways that initiate hip joint degeneration secondary to abnormal biomechanics. An animal model would also facilitate different interventional treatments that could be tested in a rigorous and controlled environment. The dog model exhibits several important characteristics that make it valuable as a pre‐clinical animal model for human DDH. Dogs are naturally prone to develop canine hip dysplasia (CHD), which is treated in a similar manner as in humans. Comparable to human DDH, CHD is considered a pre‐OA disease; if left untreated it will progress to OA. However, progression to OA is significantly faster in dogs than humans, with progression to OA within 1–2 years of age, associated with their shorter life span compared to humans. Animal studies could potentially reveal the underlying biochemical pathway(s), which can inform refined treatment modalities and provide opportunities for new treatment and prevention targets. Herein, we review the similarities and differences between the two species and outline the argument supporting CHD as an appropriate pre‐clinical model of human DDH.


Journal of The American Academy of Orthopaedic Surgeons | 2016

Femoral deformity may be more predictive of hip range of motion than severity of acetabular disease in patients with acetabular dysplasia: An analysis of the ANCHOR cohort

Peter D. Fabricant; Wudbhav N. Sankar; Mark A. Seeley; Paul E. Beaulé; John C. Clohisy; Young-Jo Kim; Michael B. Millis; Christopher L. Peters; David A. Podeszwa; Perry L. Schoenecker; Rafael J. Sierra; Ernest L. Sink; Daniel J. Sucato; Ira Zaltz

Background: It is generally believed that acetabular dysplasia (AD) is associated with increased hip range of motion (ROM). The purpose of this study was to investigate the associations between dysplasia severity and hip ROM in a large multicenter cohort.Methods: A prospective registry of patients undergoing periacetabular osteotomy for symptomatic AD by 1 of 13 surgeons was used to analyze 1,051 patients (mean age, 26 ± 10 years). Multivariable linear regression modeling was used to investigate for associations between dysplasia severity (severe, <5°; moderate, 5° to 15°; mild, >15°), &agr; angle, and hip ROM.Results: When controlling for age, sex, body mass index, and &agr; angle, only internal (&agr; = 1.94; P = 0.005) and external (&agr; = −2.63; P < 0.001) rotation in extension were significantly different between groups with increasing dysplasia severity. Alpha angle was greater for those with severe AD compared with subjects with mild disease (60° ± 16° versus 57° ± 15°; P = 0.038). Alpha angle was also significantly correlated with rotational ROM parameters (internal and external rotation in flexion and extension) (Pearson r, range: −0.077 to −0.216; P < 0.05 for all), but not with linear motion.Conclusions: Internal rotation in extension was directly associated with dysplasia severity, whereas external rotation in extension was inversely associated. Furthermore, &agr; angle was greater with increasing dysplasia severity and predictive of rotational ROM parameters. Taken together, these data suggest that femoral-sided deformity, including &agr; angle and possibly femoral version, may be responsible for differences in ROM based on dysplasia severity.Level of Evidence: Level III, Prognostic


Archive | 2018

Combined Periacetabular and Proximal Femoral Osteotomies for Healed Perthes

Perry L. Schoenecker; John C. Clohisy

Following the occurrence and healing of Legg-Calve-Perthes (LCP) in childhood, residual hip joint deformity of variable severity can occur, which is characterized by morphological features of both femoral acetabular impingement (FAI) and variable secondary relative acetabular deficiency. The femoral head is enlarged and aspherical and characteristically pathologically impinges against the acetabulum in hip flexion, in internal rotation in flexion and abduction. It also typically impinges in adduction. The femoral neck is relatively short, the greater trochanter high riding resulting in a functional coxa vara. The high-riding trochanter also potentiates both abductor insufficiency and extra-articular impingement. Secondarily, the acetabulum variably remodels in response to its long-standing articulation with a post-Perthes enlarged aspherical femoral head. If the acetabulum is dysplastic, both femoral head instability and labral-chondral rim overload can occur.


Journal of hip preservation surgery | 2018

Trends of hip arthroscopy in the setting of acetabular dysplasia

Jacob A. Haynes; Cecilia Pascual-Garrido; Tonya W An; Jeffrey J. Nepple; Paul E. Beaulé; John C. Clohisy; Young-Jo Kim; Michael B. Millis; Jeffrey Nepple; Eduardo N. Novais; Christopher L. Peters; David A. Podeszwa; Perry L. Schoenecker; Rafael J. Sierra; Ernest L. Sink; Daniel J. Sucato; Robert T. Trousdale; Ira Zaltz

ABSTRACT Hip arthroscopy is increasingly utilized in the treatment of symptomatic intra-articular hip pathology. Unaddressed development dysplasia of the hip (DDH) is thought to be associated with failure after hip arthroscopy. The aims of this study were (i) to identify the prevalence of previous failed hip arthroscopy in patients undergoing a periactebaular osteotomy (PAO) for the treatment of symptomatic acetabular dysplasia, (ii) report on the temporal trend of failed ipsilateral hip arthroscopy in patients undergoing PAO and (iii) to determine clinical and radiographic characteristics associated with utilization of isolated hip arthroscopy in patients with acetabular dysplasia. We identified 139 patients undergoing PAO who had a history of a prior ipsilateral hip arthroscopy. A comparison group of 1505 patients with a diagnosis of acetabular dysplasia, who underwent PAO alone without any prior ipsilateral surgery during the study period was used. Clinical characteristics, radiographic and intraoperative findings were compared between cohorts. From 2008 to 2015, the rate of previous failed hip arthroscopy in patients undergoing subsequent PAO increased steadily until 2013 with a maximum of 12%. Patients in the study group had mild dysplasia with significantly higher LCEA (17.2° versus 11.3°; Pu2009<u20090.001) and ACEA (15.6° versus 10.8°; Pu2009<u20090.001), a lower acetabular inclination (14.0° versus 19.0°; Pu2009<u20090.001). The findings illustrate a constant increase in the rate of failed hip arthroscopy in the setting of acetabular dysplasia from 2008 till 2013. Female sex and mild dysplasia were associated with use of isolated hip arthroscopy in the setting of acetabular dysplasia.


Journal of hip preservation surgery | 2017

Hip dysplasia in wrestlers: three lessons learned

J. W. Thomas Byrd; John C. Clohisy; Young-Jo Kim; F. Winston Gwathmey; Kay S. Jones; Michael B. Millis

Abstract Hip problems due to dysplasia are commonly associated with female athletes in sports demanding supraphysiologic motion, such as ballet, gymnastics and figure skating. However, hip problems are rarely mentioned among wrestlers, a male sport in which flexibility is advantageous. Dysplasia may have a mostly unrecognized prevalence among wrestlers that can lead to problems and benefit from reorientation periacetabular osteotomy (PAO). Study design in this research is Level 4 evidence case reports. Three consecutive intercollegiate wrestlers ages 20, 21 and 22u2009years underwent PAO for dysplasia and are reported. Two underwent concomitant arthroscopy. Each returned successfully to intercollegiate wrestling at 6, 8 and 11u2009months. There were no complications. This work concludes that dysplasia has an unknown but mostly unrecognized prevalence among wrestlers. With proper recognition and treatment with PAO, there is a reasonable expectation that they could return to wrestling.


Journal of Bone and Joint Surgery, American Volume | 2016

Contemporary Strategies for Rapid Recovery Total Hip Arthroplasty.

Jeffrey B. Stambough; Paul E. Beaulé; Ryan M. Nunley; John C. Clohisy

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Michael B. Millis

Boston Children's Hospital

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Young-Jo Kim

Boston Children's Hospital

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Daniel J. Sucato

Texas Scottish Rite Hospital for Children

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David A. Podeszwa

Texas Scottish Rite Hospital for Children

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Ernest L. Sink

Boston Children's Hospital

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