John C. Holder

Computed tomographic discography in the evaluation of extreme lateral disc herniation.

Thin section, high resolution computed tomographic (CT) scans of the lumbar spine produce images that can show herniated intervertebral discs without intravenous or intrathecal contrast enhancement. With this technique, the diagnosis of posterolateral and midline herniation has been greatly facilitated. This communication reports the use of CT discography in the preoperative evaluation of two patients who were shown at discography and proven at operation to have extreme lateral disc herniations.

31P NMR of phospholipid metabolites in prostate cancer and benign prostatic hyperplasia

1H MRSI in vivo is increasingly being used to diagnose prostate cancer noninvasively by measurement of the resonance from choline‐containing phospholipid metabolites. Although 31P NMR in vivo or in vitro is potentially an excellent method for probing the phospholipid metabolites prominent in prostate cancer, it has been little used recently. Here, we report an in vitro 31P NMR comparison of prostate cancer and benign prostatic hyperplasia, focusing on the levels of the major phospholipid metabolites. Unlike phosphocholine and glycerophosphocholine, phosphoethanolamine and glycerophosphoethanolamine (and their ratio) were significantly different between cancer and benign prostatic hyperplasia. The high level of phosphoethanolamine+glycerophosphoethanolamine relative to phosphocholine+glycerophosphocholine suggests that the former may be significant contributors to the “total choline” resonance observed by 1H MRSI in vivo. Magn Reson Med, 2010.

Loin pain hematuria syndrome

Loin pain hematuria syndrome occurs primarily in young women and is manifested by recurrent loin pain, hematuria, and abnormal renal vasculature. This syndrome was first described in 1967 by Little in the British literature. Since that time, approximately 60 cases have been reported. In this paper, we describe a case and provide a pertinent review of the literature concerning diagnosis and treatment.

Calcified Pheochromocytoma in Von Hippel-lindau Syndrome

AbstractUrologic manifestations of the von Hippel-Lindau syndrome include benign and malignant renal tumors and cysts, epididymal cysts and adenomas, adrenal cortical tumors and pheochromocytomas. A rare case of a calcified pheochromocytoma in a patient with the von Hippel-Lindau syndrome is reported.

Needle placement of myelography.

Proper placement of the entire bevel of the spinal needle within the subarachnoid space at myelography is necessary to prevent partial extra-arachnoid deposition of the contrast medium. A Cuatico aspiration cannula passed through the spinal needle at the time of spinal puncture serves to indicate the depth of the needle tip within the subarachnoid space.