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Dive into the research topics where John E. Mrochek is active.

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Featured researches published by John E. Mrochek.


Journal of Chromatography A | 1976

High-resolution liquid chromatographic analysis of methylated purine and pyrimidine bases in transfer RNA

Duane B. Lakings; T. Phillip Waalkes; John E. Mrochek

Methylated and major purine and pyrimidine bases were separated and quantified by high-resolution liquid chromatography after hydrolyzing transfer ribonucleic acids (tRNAs). Separation was accomplished by eluting the hydrolyzed samples from an anion-exchange column with a concentration gradient of ammonium acetate at pH 9.2. Isolated sample of tRNA were hydrolyzed to the free bases with a trifluoroacetic acid-formic acid mixture of 200 degrees. Detection limits of 100-200 ng/ml were measured for the methylated bases; analytical data are reported for ten methylated bases plus the four major bases of calf liver and rat liver tRNA.


Clinical Chemistry | 1976

Metabolic response of humans to ingestion of nicotinic acid and nicotinamide.

John E. Mrochek; Robert L. Jolley; Donald S. Young; William J. Turner


Clinical Chemistry | 1971

Separation and Identification of Urinary Constituents by Use of Multiple-Analytical Techniques

John E. Mrochek; W. C. Butts; W. T. Rainey; C. A. Burtis


Journal of the National Cancer Institute | 1973

Urinary Excretion by Cancer Patients of the Nucleosides N2,N2-Dimethylguanosine, 1-Methylinosine, and Pseudouridine

T. Phillip Waalkes; Stanley R. Dinsmere; John E. Mrochek


Journal of the National Cancer Institute | 1974

Analytic Techniques in the Separation and Identification of Specific Purine and Pyrimidine Degradation Products of tRNA: Application to Urine Samples From Cancer Patients

John E. Mrochek; Stanley R. Dinsmore; T. Phillip Waalkes


Clinical Chemistry | 1976

Protein-bound carbohydrates in breast cancer. Liquid-chromatographic analysis for mannose, galactose, fucose, and sialic acid in serum.

John E. Mrochek; Stanley R. Dinsmore; D C Tormey; T P Waalkes


Fusion Technology | 1990

Measurement of Excess Heat and Apparent Coincident Increases in the Neutron and Gamma-Ray Count Rates During the Electrolysis of Heavy Water

Charles D. Scott; John E. Mrochek; Timothy C. Scott; Gordon E. Michaels; Eugene Newman; Milica Petek


Archive | 1982

System for analyzing coal-liquefaction products

Stanley R. Dinsmore; John E. Mrochek


Clinical Chemistry | 1978

Separation and analysis of arylsulfatase isoenzymes in body fluids of man.

W D Bostick; Stanley R. Dinsmore; John E. Mrochek; T P Waalkes


Clinical Chemistry | 1975

Liquid-Chromatographic Analysis for Neutral Carbohydrates in Serum Glycoproteins

John E. Mrochek; Stanley R. Dinsmore; T. Phillip Waalkes

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Stanley R. Dinsmore

Oak Ridge National Laboratory

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Charles D. Scott

Oak Ridge National Laboratory

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T. Phillip Waalkes

Oak Ridge National Laboratory

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Donald S. Young

University of Pennsylvania

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T P Waalkes

Oak Ridge National Laboratory

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Timothy C. Scott

Oak Ridge National Laboratory

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Carl A. Burtis

Oak Ridge National Laboratory

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D C Tormey

Oak Ridge National Laboratory

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