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John E. Tellew

Bristol-Myers Squibb

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Publication

Featured researches published by John E. Tellew.

Tetrahedron Letters | 2002

Vicarious nucleophilic substitution of 1-benzyl-5-nitroimidazole, application to the synthesis of 6,7-dihydroimidazo[4,5-d][1,3]diazepin-8(3H)-one

Bang-Chi Chen; Sam T. Chao; Joseph E. Sundeen; John E. Tellew; Saleem Ahmad

Reaction of 1-benzyl-5-nitroimidazole with carbanion generated from chloroform and potassium tert-butoxide afforded 1-benzyl-4-dichloromethyl-5-nitroimidazole in 72% yield. This vicarious nucleophilic substitution reaction was successfully applied to the synthesis of 6,7-dihydroimidazo[4,5-d][1,3]diazepin-8(3H)-one, an important intermediate in the synthesis of natural and biologically active compounds.

Archive | 1999

Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists

Natesan Murugesan; John E. Tellew; John E. Macor; Zhengxiang Gu

Journal of Medicinal Chemistry | 2005

Dual Angiotensin II and Endothelin A Receptor Antagonists: Synthesis of 2‘-Substituted N-3-Isoxazolyl Biphenylsulfonamides with Improved Potency and Pharmacokinetics

Natesan Murugesan; Zhengxiang Gu; Leena Fadnis; John E. Tellew; Rose A. Baska; Yifan Yang; Sophie Beyer; Hossain Monshizadegan; Kenneth E.J. Dickinson; Maria T. Valentine; W. Griffith Humphreys; Shih-Jung Lan; William R. Ewing; Kenneth E. Carlson; Mark C. Kowala; and Robert Zahler; John E. Macor

Journal of Medicinal Chemistry | 2002

Discovery of N-Isoxazolyl Biphenylsulfonamides as Potent Dual Angiotensin II and Endothelin A Receptor Antagonists

Natesan Murugesan; John E. Tellew; Zhengxiang Gu; Bridgette L. Kunst; Leena Fadnis; Lyndon A. M. Cornelius; Rose A. Baska; Yifan Yang; Sophie Beyer; Hossain Monshizadegan; Kenneth E.J. Dickinson; Balkrushna Panchal; Maria T. Valentine; Saeho Chong; Richard A. Morrison; Kenneth E. Carlson; James R. Powell; Suzanne Moreland; Joel C. Barrish; and Mark C. Kowala; John E. Macor

Journal of Pharmacology and Experimental Therapeutics | 2004

Novel Dual Action AT1 and ETA Receptor Antagonists Reduce Blood Pressure in Experimental Hypertension

Mark C. Kowala; Natesan Murugesan; John E. Tellew; Kenneth E. Carlson; Hossain Monshizadegan; Carol S. Ryan; Zhengxiang Gu; Bridgette Kane; Leena Fadnis; Rose A. Baska; Sophie Beyer; Susan Arthur; Kenneth E.J. Dickinson; Donglu Zhang; Mark H. Perrone; Pam Ferrer; Mary R. Giancarli; Jergen Baumann; Eileen Bird; Balkrushna C. Panchal; Yifan Yang; Nick C. Trippodo; Joel C. Barrish; John E. Macor

Bioorganic & Medicinal Chemistry Letters | 2003

Discovery of 4'-[(imidazol-1-yl)methyl]biphenyl-2-sulfonamides as dual endothelin/angiotensin II receptor antagonists.

John E. Tellew; Rose A. Baska; Sophie Beyer; Kenneth E. Carlson; Lyndon A. M. Cornelius; Leena Fadnis; Zhengxiang Gu; Bridgette L. Kunst; Mark C. Kowala; Hossain Monshizadegan; Natesan Murugesan; Carol S. Ryan; Maria T. Valentine; Yifan Yang; John E. Macor

19th International Congress on Heterocyclic Chemistry#R##N#Book of Abstracts | 2003

Heteroarylsulfonamido Biphenyls as Potent Dual Antagonists Blocking Angiotensin and Endothelin Receptors and Useful as Novel Anti-hypertensives

John E. Macor; Natesan Murugesan; John E. Tellew; Zhengxiang Gu; Bridgette L. Kunst; Leena Fadnis; Lyndon A. M. Cornelius; Kenneth E. Carlson; Mark C. Kowala

Archive | 2000

Biphényl-sulfonamides comme antagonistes jumalées des récepteurs endothélines.

John E. Tellew; Natesan Murugesan; John E. Macor; Zhengxiang Gu

Archive | 2000

Biphenyl sulfonamides utilises comme doubles antagonistes des recepteurs de l'angiotensine et de l'endotheline

Natesan Murugesan; John E. Tellew; John E. Macor; Zhengxiang Gu

Archive | 1999

Biphenyl sulfonamides en tant que doubles antagonistes de recepteurs d'angiotensine et d'endotheline

Natesan Murugesan; John E. Tellew; John E. Macor; Zhengxiang Gu

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John E. Macor

Bristol-Myers Squibb

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Natesan Murugesan

Bristol-Myers Squibb

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Zhengxiang Gu

Bristol-Myers Squibb

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Kenneth E. Carlson

Bristol-Myers Squibb

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Leena Fadnis

Bristol-Myers Squibb

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Hossain Monshizadegan

Bristol-Myers Squibb

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Mark C. Kowala

Bristol-Myers Squibb

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Rose A. Baska

Bristol-Myers Squibb

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Sophie Beyer

Bristol-Myers Squibb

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Yifan Yang

Bristol-Myers Squibb

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