John H. Fitchen
Scripps Research Institute
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Featured researches published by John H. Fitchen.
Vaccine | 1995
John H. Fitchen; Roger N. Beachy; Mich B. Hein
A modified tobacco mosaic virus (TMV) was used to direct the synthesis of TMV coat protein hybrids containing a 13 amino acid sequence of the murine zona pellucida ZP3 protein. This hybrid protein was found to be robust and accumulate to high concentrations in inoculated plants. Virus-like particles containing the hybrid coat protein could be readily purified from infected plant tissue. Parenteral immunization with these virus-like particles as antigen resulted in serum antibody recognizing ZP3 epitope in C57BL/6J and BALB/cBy mice. The antibodies recognized synthetic ZP3 peptide and the authentic murine ZP3 glycoprotein. Antibodies were recruited in vivo to the zone pellucida in female mice.
Annual Review of Microbiology | 1993
John H. Fitchen; Roger N. Beachy
Proceedings of the National Academy of Sciences of the United States of America | 1999
Moses Koo; Mohammed Bendahmane; Gerard A. Lettieri; Alyssa D. Paoletti; Thomas E. Lane; John H. Fitchen; Michael J. Buchmeier; Roger N. Beachy
Journal of Virology | 1997
Mohammed Bendahmane; John H. Fitchen; Guangming Zhang; Roger N. Beachy
Archive | 1995
John H. Fitchen; Roger N. Beachy
Annals of the New York Academy of Sciences | 1996
Roger N. Beachy; John H. Fitchen; Mich B. Hein
Virology | 1995
W.Gregg Clark; John H. Fitchen; Roger N. Beachy
Archive | 1997
Andrew C. Hiatt; Mich B. Hein; John H. Fitchen
Archive | 1997
Mich B. Hein; Andrew C. Hiatt; John H. Fitchen
Archive | 1998
Mich B. Hein; Andrew C. Hiatt; John H. Fitchen