John Otto Naples

Preparation and use of latex-coated resins for anion chromatography☆

Abstract A procedure is described for the preparation of low-capacity anion-exchange resins for use in single-column ion chromatography. The resins are prepared by hydrophobically coating an anion-exchanging latex onto unfunctionalized resins made by Rohm & Haas. The resin exchange capacities are varied by changing the concentration of the sodium chloride or latex in the coating solution. Various resin matrices can be coated and capacities from 5 to over 400 μ equiv./g are obtained. The mechanism of latex adsorption is discussed and several highly efficient anion separations are presented.

Ion exchange resins

This article has no abstract. Keywords: hydrolysis; acetonide formation; methyl glycosides; amide formation; esterification; rearrangement; ketone condensations; phenol condensations; hydration of acetylenes; hydrolysis; free base from the hydrochloride; dehydrohalogenation; hydration; condensations; displacements; epoxide formation; solid-phase peptide synthesis; ion-exchange chromatography; acidic resins; solid-phase peptide synthesis; anion-exchange celluloses; cyclodehydration; esterification; acetal and ketal synthesis; Raney nickel catalysts; cyclopropanes via abnormal Hofmann elimination; demethylation of aryl methyl sulfides; 2,5-dimethylfurane; enol ethers; ketals; acetals and ketals; selective ketalization; γ-butyrolactones; dimerization of vinylarenes; cyclization of costunolide; esters; solid-phase peptide synthesis; quaternary ammonium hydroxides; alkyl fluorides by exchange from alkyl halides or methanesulfonates; nucleophilic substitutions; F−-anion exchange resins; tetrahydropyranylation; ketalization; mixed acid–base ion-exchange resins; solid phase-transfer reactions; hydrolysis of amides and hydrazides; hydrolysis of acetals; cleavage of hydrazones, oximes, and semicarbazones; esterification; cyclization; Henry reaction; deacetalization and dethioacetalization; monoacylation of 1,ω-diols; esterification; cyclizations; desulfinylation; deoxygenation of epoxy ketones; reactions; oxidation; triazenes

Low-capacity latex-coated resins for anion chromatography

Abstract Methods are described for coating latexes bearing a quaternary ammonium group onto spherical, non-porous polymeric resins. Exchange capacity of the coated resins is controlled by the amount of acetonitrile in the coating slurry and on the amount of latex in the slurry. A capacity range of 11–85 μequiv./g was obtained. Excellent chromatographic separations were obtained with columns packed with the coated resins. Sulfate is shown to elute before bromide and nitrate. As much as 40% methanol can be incorporated into the eluent without damaging the chromatographic column.