John R. Person

Subcutaneous morphoea: a clinical study of sixteen cases

Sixteen patients had biopsy‐proved inflammatory sclerosis of the panniculus or fascia, which usually was seen in a generalized distribution. Although the sclerosis involved the digits of five patients, it was the result of centrifugal spread of the sclerosis and was not accompanied by ulcers, calcinosis, distal phalangeal resorption or telangiectasia. Four patients may have had digital vasopasm in the extremities involved in the sclerotic process. Five patients also had cutaneous lesions of dermal morphoea or lichen sclerosus et atrophicus. Four patients had a reduced carbon monoxide diffusing capacity, and one of these had roentgenographic evidence of pulmonary fibrosis. In three patients, oesophageal motility or barium swallow studies showed evidence of sclerodermatous changes. The sclerotic process was a contributory cause of the death of one patient. Five patients had peripheral eosinophilia. Six patients seemed to have responded to anti‐inflammatory agents.

Bullous pemphigoid and psoriasis: does subclinical bullous pemphigoid exist?

Four cases are presented in which probable bullous pemphigoid and probable psoriasis co‐existed. One case represents a simple coincidence ofthe two diseases. In the other three cases, the bullous lesions were transient and seemed to be induced by elements ofthe Gocckerman regimen. The hypothesis is presented that these three cases represent a subclinical form of bullous pempbigoid induced by the irritant effects of coal tar, ultraviolet light, the reduced barrier function ofa pre‐existing derma‐tosis, or a combination of these factors.

Angiolymphoid hyperplasia with eosinophilia may respond to pentoxifylline

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