Network


Latest external collaboration on country level. Dive into details by clicking on the dots.

Hotspot


Dive into the research topics where John T. Payne is active.

Publication


Featured researches published by John T. Payne.


Lasers in Surgery and Medicine | 1999

Comparison of cortical bone ablations by using infrared laser wavelengths 2.9 to 9.2 μm

George M. Peavy; Lou Reinisch; John T. Payne; Vasan Venugopalan

The purpose of this study was to compare the ablation of cortical bone at wavelengths across the near and midinfrared region.


British Journal of Cancer | 2000

Treatment of canine oral squamous cell carcinomas with photodynamic therapy.

Dudley L. McCaw; Eric R. Pope; John T. Payne; Matthew K. West; Robert V. Tompson; Deborah Tate

Eleven dogs with naturally occurring oral squamous cell carcinomas were treated with photodynamic therapy (PDT) using Photochlor (HPPH) as the photosensitizer. The largest length of the tumours measured in a two-dimensional plane ranged from 0.9 to 6.8 cm. Seven of the tumours invaded underlying bone as determined by radiograph appearance. Photochlor was injected intravenously at a dose of 0.3 mg kg–1. Forty-eight hours later the tumours were treated. Tumours with a surface to base depth of greater than 1 cm were surgically reduced to less than 1 cm. Irradiation with 665 nm light with an energy density of 100 J cm–2was administered. Eight dogs were considered cured with no tumour recurrence for at least 17 months after treatment. Local treatment of oral squamous cell carcinomas with PDT appears to give results similar to those obtained with surgical removal of large portions of the mandible or maxilla. The cosmetic results with PDT are superior to those of radical surgical removal. The new sensitizer, Photochlor, appears effective for oral squamous carcinomas with results similar to those reported for other sensitizers.


Lasers in Surgery and Medicine | 1996

Pharmacokinetics of pyropheophorbide‐a‐hexyl ether in the dog

John T. Payne; Dudley L. McCaw; Stan W. Casteel; Donita L. Frazier; Kevin Rogers; Robert V. Tompson

Pyropheophorbide‐a‐hexyl ether (HPPH) is a new compound being investigated for use as a photosensitizer for photodynamic therapy; however, the pharmacokinetics are not known for any of the target species likely to be treated with this drug. The objective of this study was to determine the pharmacokinetic parameters of this drug prior to institution of a clinical trial in canine patients with various cancers. Study design, Materials and Methods. HPPH (0.3mg/kg I.V.) was administered to 12 dogs and blood samples were drawn at intervals for 24 hours and plasma HPPH concentrations were determined. Pharmacokinetic parameters were calculated for each dog.


Veterinary Clinics of North America-small Animal Practice | 1993

Stifle Joint Anatomy and Surgical Approaches in the Dog

John T. Payne; Gheorghe M. Constantinescu

This article reviewed the pertinent anatomy and surgical approaches of the canine stifle joint. Anatomically correct approaches to this joint provide for relatively atraumatic entry into the joint, while providing adequate exposure to complete the intra-articular parts of the surgical procedure. Atraumatic surgical exposures provide for less postoperative pain and a better outcome to any surgical procedure.


Archive | 1996

A Swine Model for Determining the Bioavailability of Lead from Contaminated Media

Stan W. Casteel; Ross P. Cowart; Christopher P. Weis; Gerry Henningsen; Eva Hoffman; William J. Brattin; Matthew F. Starost; John T. Payne; Steven L. Stockham; Stephen V. Becker; James R. Turk

Bioavailability is the portion of a chemical dose that enters the systemic circulation from an administered dosage form. Enteric absorption depends on the physical and chemical properties and associated matrix, e.g., soil, slag, food, water, of the chemical. For our purposes, two separate connotations of the term bioavailability will be clarified. Absolute bioavailability is synonymous with the oral absorption fraction (AF0) for a specific chemical from its associated matrix. For example, if lead (Pb) from lead acetate (PbAc) is 50% absorbed from drinking water and lead from lead sulfide (PbS) is 25% absorbed from soil, the absolute bioavailabilities or AF0s of lead would be 50 and 25%, respectively. Relative bioavailability (RBA) refers to the absorption of one chemical form compared to some other reference form. For example, if lead acetate in drinking water is the reference form of lead, then the RBA of lead from lead sulfide would be 25/50, or 50% compared to lead from lead acetate.


Veterinary Clinics of North America-small Animal Practice | 1995

General Management Considerations for the Trauma Patient

John T. Payne

Proper evaluation, nursing care, physical therapy, and attention to the patients general comfort are essential to the successful management of animals with severe trauma. Evaluation is important because failure to identify all injuries early in the management of a trauma patient may have unfavorable effects on the eventual outcome of the case. Once therapy is underway, ensuring the patients comfort, maintaining fluid and electrolyte balance, and providing a well-planned rehabilitation program are essential to speed an enhance the recovery of these patients.


Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems V | 1995

Treatment of naturally occuring hemangiopericytoma and oral squamous cell carcinoma in dogs using surgery and photodynamic therapy with HPPH as a photosensitizer

John T. Payne; Dudley L. McCaw; Kevin Rogers; Robert V. Tompson

Pyropheophorbide-a-hexyl ether (HPPH) is a new photosensitizer for use with photodynamic therapy (PDT) that has shown promise in laboratory animals. PDT, using this drug, is being used to treat canine patients afflicted with hemangiopericytoma and oral squamous cell carcinoma (SCC) at the University of Missouri-Columbia College of Veterinary Medicine. To date, 11 dogs with hemangiopericytoma and 5 dogs with oral SCC have been treated using a combination of surgery and PDT. Thus far, there have been no serious complications attributable to the treatment. Two dogs have had recurrences of the hemangiopericytoma and there have been no recurrences of SCC with a median follow time of 5 months. Both recurrent hemangiopericytomas were in patients with large tumors that had previous surgery. This study is ongoing and no conclusions have been reached; however several observations are noted. It appears that PDT using HPPH is safe is dogs, and may decrease the recurrence rate of Hemangiopericytomas. In dogs with oral SCC, the treatment is effective is causing necrosis and sloughing of the tumor tissue, and recurrences have not been noted on follow-ups up to 6 months.


Veterinary Surgery | 2016

Outcome of Tibial Closing Wedge Osteotomy in 55 Cranial Cruciate Ligament-Deficient Stifles of Small Dogs (<15 kg)

Kathryn A. Campbell; John T. Payne; Michael T. Doornink; Jamie Haggerty

OBJECTIVE To describe the outcome of cranial closing wedge osteotomy (CWO) of the tibia for treatment of cranial cruciate ligament (CrCL)-deficient stifles in dogs with a body weight of <15 kg. STUDY DESIGN Retrospective case series. ANIMALS Forty-five client-owned dogs (n=55 stifles). METHODS Medical records (2005-2014), radiographs, and owner questionnaire were used to identify the surgical procedure performed, associated complications and outcome in 45 dogs undergoing CWO in 55 stifles. RESULTS Data for 55 stifles from 45 dogs were included. Bichon Frise was the most frequent dog breed (n=11). Mean pre- and postoperative tibial plateau angle (TPA) were 36.3° (95% CI 35.1-37.5) and 7.5° (95% CI 6.7-8.2), respectively. Pin and tension bands were placed in 38/55 stifles (69%). The most frequent complication at short-term follow-up (2 weeks) was incisional complications in 8 stifles; all resolved with systemic antibiotic administration alone. Data were available for all stifles at 8 week follow-up with an overall complication occurrence in 16/55 stifles (28%); 1 dog required revision surgery. Tibial osteotomy healing was evident on radiographs at 8 weeks postoperative in 53 stifles (96%), considered complete in 27 stifles, and good in 26 stifles. Follow-up owner questionnaire was available for 36 dogs at a mean of 24 months and 34/36 owners (94%) were satisfied with the procedure and considered their dog had a good quality of life with minimal long-term complications. CONCLUSION Dogs with a body weight <15 kg undergoing CWO for treatment of a CrCL-deficient stifle had a good outcome based on clinical status, radiographic evaluation, and owner questionnaire.


Toxicological Sciences | 1997

Bioavailability of Lead to Juvenile Swine Dosed with Soil from the Smuggler Mountain NPL Site of Aspen, Colorado

Stan W. Casteel; Ross P. Cowart; Christopher P. Weis; Gerry Henningsen; Eva Hoffman; William J. Brattin; Roberto E. Guzman; Matthew F. Starost; John T. Payne; Steven L. Stockham; Stephen V. Becker; John W. Drexler; James R. Turk


Veterinary Surgery | 1998

Biomechanical Evaluation of a Crimp Clamp System for Loop Fixation of Monofilament Nylon Leader Material Used for Stabilization of the Canine Stifle Joint

C. Collins Anderson; James L. Tomlinson; William R. Daly; William L. Carson; John T. Payne; Colette C. Wagner-Mann

Collaboration


Dive into the John T. Payne's collaboration.

Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar

Christopher P. Weis

United States Environmental Protection Agency

View shared research outputs
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar

Eva Hoffman

United States Environmental Protection Agency

View shared research outputs
Top Co-Authors

Avatar
Researchain Logo
Decentralizing Knowledge