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Publication
Featured researches published by Johnson Samuel.
Clinical Respiratory Journal | 2017
Barney Thomas Jesudason Isaac; Johnson Samuel; Dipak Mukherjee; Marcus Pittman
A 35 years old man presented with acute onset left sided pleuritic chest pain and shortness of breath. On evaluation, he was found to have an interesting chest radiograph which showed a loculated pneumothorax with collapse of the left upper lobe and lingula but fully expanded left lower lobe. He is a known asthmatic who had allergic broncho pulmonary aspergillosis (ABPA) previously with left upper lobe and lingular collapse secondary to mucous plugging. This resolved on treatment with steroids and itraconazole. An interesting combination of events is proposed to explain the current presentation. CT scan chest and blood tests confirmed this sequence of events. He was appropriately treated resulting in complete clinical and radiological recovery. The events leading to the presentation and the likely physiological background for this interesting chest radiograph are discussed.
Clinical Medicine | 2017
Barney Thomas Jesudason Isaac; Sarah E Clarke; Mohammad Saiful Islam; Johnson Samuel
Abstract Obstructive sleep apnoea (OSA), which is often overlooked in patients presenting to primary and secondary care, is an increasingly common comorbidity. The prevalence of OSA has not been studied in the unselected acute medical take. The aim of this study was to screen for the prevalence of undiagnosed OSA using the STOPBANG Questionnaire and the Epworth sleepiness scale (ESS) score in an unselected acute medical take. This was a cross-sectional study in a busy UK general hospital. Patient demographics, comorbidities, ESS and STOPBANG scores on unselected acute medical takes were reviewed and analysed to assess the prevalence of OSA. Of 93 patients screened, more than 50% were obese. The STOPBANG score was ≥3 in 73%. The ESS was significantly increased (≥11) in 20%. On multivariate analysis, ESS continued to remain independently associated with the STOPBANG score with a p-value of 0.04. The routine use of the STOPBANG questionnaire followed by an ESS score in those with a score of ≥3 may focus evaluation for undetected OSA in the acute medical care setting.
Case Reports | 2016
Barney Thomas Jesudason Isaac; Thomas McLellan; Johnson Samuel; Bernard Yung
A 66-year-old man, an asthmatic, presented with symptoms suggestive of an acute exacerbation of asthma. His arterial blood gas revealed type 1 respiratory failure (PaO2 <8 kPa or 60 mm Hg with normal or low PaCO2) with a compensated lactic acidosis. He was treated for an asthma exacerbation and sepsis. Despite treatment, his respiratory rate remained elevated although his hypoxaemia improved. There was progressive worsening of the lactic acidosis. Treatment for sepsis was augmented. Peak flow measurements were not used to assess the severity of his exacerbation nor his response to treatment. An alternate diagnosis of acute coronary syndrome with acute pulmonary oedema was made and his asthma treatment was stopped. This coincided with a decline in his serum lactate. A diagnosis of salbutamol-induced lactic acidosis (SILA) was made. SILA is a relatively common complication of salbutamol therapy in moderate/severe asthma exacerbations. It is caused by a mechanism different from the lactataemia that is associated with septic shock and life-threatening asthma.
Archive | 2017
Zaheer Mangera; Rosemary Gray; Johnson Samuel
The Indian journal of chest diseases & allied sciences | 2015
Balamugesh Thangakunam; Johnson Samuel; Basharet Ibrahim; Doug Aitchison
European Respiratory Journal | 2013
Said Isse; Prince James; Zaheer Mangera; Dipak Mukherjee; Bernard Yung; Johnson Samuel; Wadsworth Kirsten
European Respiratory Journal | 2011
Balamugesh Thangakunam; Kanwar Pannu; Kim Wilkins; Basharet Ibrahim; Bernard Yung; Dipak Mukherjee; Doug Aitchison; Johnson Samuel
american thoracic society international conference | 2010
Victoria L. Mulcahy; Lulu Tanno; Bernard Yung; Dipak Mukherjee; Johnson Samuel
american thoracic society international conference | 2010
Balamugesh Thangakunam; Nazar Alsanjari; Dipak Mukherjee; Bernard Yung; Johnson Samuel
american thoracic society international conference | 2010
Nandini Banerjee; Balamugesh Thangakunam; Basharet Ibrahim; K Wilkins; Bernard Yung; Dipak Mukherjee; Johnson Samuel
Collaboration
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Basildon and Thurrock University Hospitals NHS Foundation Trust
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