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Dive into the research topics where Jolanta Nowakowski is active.

Publication


Featured researches published by Jolanta Nowakowski.


Bioorganic & Medicinal Chemistry Letters | 1999

A new class of selective and potent inhibitors of neuronal nitric oxide synthase.

John A. Lowe; Weimin Qian; Robert A. Volkmann; Steven D. Heck; Jolanta Nowakowski; Robert B. Nelson; Charles E. Nolan; Dane Liston; Karen M. Ward; Stevin H. Zorn; Celeste Johnson; Michelle Vanase; W. Stephen Faraci; Kimberly A. Verdries; James Baxter; Shawn D. Doran; Martin Sanders; Mike Ashton; Peter John Whittle; Mark H. Stefaniak

The synthesis and SAR of a series of 6-(4-(substituted)phenyl)-2-aminopyridines as inhibitors of nitric oxide synthase are described. Compound 3a from this series shows potent and selective inhibition of the human nNOS isoform, with pharmacokinetics sufficient to provide in vivo inhibition of nNOS activity.


Archive | 1992

5-heteroyl indole derivatives

Jolanta Nowakowski


Archive | 1998

2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines

John A. Lowe; Jolanta Nowakowski; Robert A. Volkmann


Drug Development Research | 1994

Dopamine uptake inhibitory activity of novel tryptamine 5‐HT1 receptor ligands

Lorraine A. Lebel; Jolanta Nowakowski; John E. Macor; Carol B. Fox; B. Kenneth Koe


Archive | 1997

Novel muscarinic receptor agonists

Dane Liston; Jolanta Nowakowski; Anabella Villalobos; Daniel Yohannes


Archive | 1999

NEW PHARMACEUTICAL USES FOR NOS INHIBITORS

John A. Lowe; Jolanta Nowakowski; Robert A. Volkmann


Archive | 2003

Processes for preparing substituted aryl boronic acids

Stephane Caron; Jolanta Nowakowski


Archive | 2003

PROCESS FOR PREPARING ALKANESULFONYL PYRIDINES

Jolanta Nowakowski; Dieter Christian Haag


Archive | 2003

Substituted aryl boronic acids, their preparation and their precursors

Stephane Caron; Jolanta Nowakowski


Archive | 2004

Substituted pyridines via boronic acid coupling

Stephane Caron; Jolanta Nowakowski

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