Jonas A. Shulman

Errors and Hazards in the Diagnosis and Treatment of Bacterial Pneumonias

Excerpt In recent years bacterial infections of the lung have been considered prime examples of diseases conquered by chemotherapy. While there is no doubt that antibiotics have exerted a dramatic ...

Drugs Spotlight Program: Immunization for the Internist

The emphasis of immunization programs and schedules has traditionally been directed to infants and children, since most of the vaccine-preventable diseases are seen predominantly in these age groups. Immunization procedures in adults are less well defined but still of importance. Diseases for which immunizations are given before disease exposure include tetanus, diphtheria, influenza, rubella, and mumps; travelers to foreign countries may need immunizations against typhoid, cholera, yellow fever, typhus, poliomyelitis, plague, and viral hepatitis; other vaccines are available before disease exposure in unusual epidemiologic situations. After exposure to disease but before onset of symptoms, immunizations are available for rabies, viral hepatitis, and measles. After the onset of clinical illness, passive immunization should be given for tetanus, diphtheria, and botulism. This paper summarizes current practices for active and passive immunization against these diseases in adults.

Absorption of endogenous pyrogens by bentonite.

Summary Endogenous pyrogen (E.P.) in serum from animals given endotoxin or New-castle disease virus and in leukocytic exudates was inactivated by absorption with bentonite. Concentration of lysozyme in serum and exudates paralleled that of E.P. The pyrogenicity of typhoid vaccine and NDV was not affected by absorption with bentonite.