Jonathan Duffield
Arena Pharmaceuticals, Inc.
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Publication
Featured researches published by Jonathan Duffield.
Bioorganic & Medicinal Chemistry Letters | 2008
Vincent J. Santora; Jonathan A. Covel; Rena Hayashi; Brian J. Hofilena; Jason B. Ibarra; Michelle D. Pulley; Michael I. Weinhouse; Dipanjan Sengupta; Jonathan Duffield; Graeme Semple; Robert R. Webb; Carleton R. Sage; Albert S. Ren; Guilherme Pereira; Jens Knudsen; Jeffrey E. Edwards; Marissa Suarez; John Frazer; William Thomsen; Erin K. Hauser; Kevin Whelan; Andrew J. Grottick
A new family of Histamine H(3) receptor antagonists (5a-t) has been prepared based on the structure of the natural product Conessine, a known H(3) antagonist. Several members of the new series are highly potent and selective binders of rat and human H(3) receptors and display inverse agonism at the human H(3) receptor. Compound 5n exhibited promising rat pharmacokinetic properties and demonstrated functional antagonism of the H(3) receptor in an in-vivo pharmacological model.
Tetrahedron Letters | 2005
Alex Romero; Chang-Hsing Liang; Yu-Hung Chiu; Sulan Yao; Jonathan Duffield; Steven J. Sucheck; Ken Marby; David Rabuka; Po Yee Leung; Youe-Kong Shue; Yoshi Ichikawa; Chan-Kou Hwang
Bioorganic & Medicinal Chemistry Letters | 2005
Chang-Hsing Liang; Alex Romero; David Rabuka; Paulo W.M. Sgarbi; Kenneth Marby; Jonathan Duffield; Sulan Yao; Mayling L. Cheng; Yoshi Ichikawa; Pamela Sears; Changyong Hu; San-Bao Hwang; Youe-Kong Shue; Steven J. Sucheck
Archive | 2007
Tawfik Gharbaoui; Dipanjan Sengupta; Ashwin M. Krishnan; Nainesh Shah; Ryan M. Hart; Mark Macias; Edward A. Lally; Jonathan Duffield
Archive | 2007
Vincent J. Santora; Jonathan A. Covel; Rena Hayashi; Robert R. Webb; Albert S. Ren; Weichao G. Chen; Jonathan Duffield; Jason B. Ibarra; Michelle D. Pulley; Graeme Semple; Michael I. Weinhouse
Archive | 2007
Derin C. D'amico; Benny C. Askew; Yoshitaka Ichikawa; Jonathan Duffield
Archive | 2004
Jonathan Duffield; Kenneth Marby; Sean O'hare; Chan-Kou Hwang; Yoshitaka Ichikawa
Archive | 2010
Yuan-Ting Chen; Ming-His Chiou; Chi-Jen Frank Du; Jonathan Duffield; Franklin W. Okumu; Youe-Kong Shue; Mei-Chiao Wu; − チャオ ウー、メイ; オクム、フランクリン、ダブリュー．; − コン シュウ、ユー; − ティン チェン、ユアン; − ヒス チョウ、ミン; − イェン、フランク デュ、チー; デュフィールド、ジョナサン、ジェームズ
Archive | 2009
Youe-Kong Shue; Chi-Jen Frank Du; Ming-Hsi Chiou; Mei-Chiao Wu; Yuan-Ting Chen; Franklin W. Okumu; Jonathan Duffield
Archive | 2007
Tawfik Gharbaoui; Dipanjan Sengupta; Ashwin M. Krishnan; Nainesh Shah; Mark Macias; Ryan M. Hart; Edward A. Lally; Jonathan Duffield
Collaboration
Dive into the Jonathan Duffield's collaboration.
