Jonathan Moran
Trinity College, Dublin
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BJA: British Journal of Anaesthesia | 2016
Jonathan Moran; Fiona Wilson; Emer Guinan; Paul McCormick; Juliette Hussey; Jeanne Moriarty
BACKGROUND Cardiopulmonary exercise testing (CPET) is used as a preoperative risk-stratification tool for patients undergoing non-cardiopulmonary intra-abdominal surgery. Previous studies indicate that CPET may be beneficial, but research is needed to quantify CPET values protective against poor postoperative outcome [mortality, morbidity, and length of stay (LOS)]. METHODS This systematic review aimed to assess the ability of CPET to predict postoperative outcome. The following databases were searched: PubMed, EMBASE, PEDro, The Cochrane Library, Cinahl, and AMED. Thirty-seven full-text articles were included. Data extraction included the following: author, patient characteristics, setting, surgery type, postoperative outcome measure, and CPET outcomes. RESULTS Surgeries reviewed were hepatic transplant and resection (n=7), abdominal aortic aneurysm (AAA) repair (n=5), colorectal (n=6), pancreatic (n=4), renal transplant (n=2), upper gastrointestinal (n=4), bariatric (n=2), and general intra-abdominal surgery (n=12). Cardiopulmonary exercise testing-derived cut-points, peak oxygen consumption ([Formula: see text]), and anaerobic threshold (AT) predicted the following postoperative outcomes: 90 day-3 yr survival (AT 9-11 ml kg(-1) min(-1)) and intensive care unit admission (AT <9.9-11 ml kg(-1) min(-1)) after hepatic transplant and resection, 90 day survival after AAA repair ([Formula: see text] 15 ml kg(-1) min(-1)), LOS and morbidity after pancreatic surgery (AT <10-10.1 ml kg(-1) min(-1)), and mortality and morbidity after intra-abdominal surgery (AT 10.9 and <10.1 ml kg(-1) min(-1), respectively). CONCLUSION Cardiopulmonary exercise testing is a useful preoperative risk-stratification tool that can predict postoperative outcome. Further research is needed to justify the ability of CPET to predict postoperative outcome in renal transplant, colorectal, upper gastrointestinal, and bariatric surgery.
Journal of Clinical Anesthesia | 2016
Jonathan Moran; Fiona Wilson; Emer Guinan; Paul McCormick; Juliette Hussey; Jeanne Moriarty
STUDY OBJECTIVE To assess the ability of field tests of exercise tolerance, such as the 6-minute walk test (6MWT) and incremental shuttle walk test (ISWT), to predict postoperative outcome following intra-abdominal surgery. DESIGN A systematic review. SETTING A hospital-affiliated university. MEASUREMENTS The following databases were searched: AMED, CINAHL, EMBASE, PEDro, PubMed/MEDLINE, and The Cochrane Library. Six full-text articles were included. Data extraction included author, population demographics, surgery type, postoperative outcome measure, and field test results. The risk of bias was performed using the Quality in Prognosis Studies tool. RESULTS Surgical procedures reviewed were colorectal (n=3), upper gastrointestinal (n=1), and intra-abdominal surgery (n=2). Field tests of exercise tolerance showed little ability to predict postoperative mortality; however, the overall rate of mortality was low. Patients achieving lower distances on the ISWT tended to have longer hospital stays and an increased risk of overall complications. The 6MWT does not appear able to predict postoperative cardiac or pulmonary complications; however, it may be suitable to predict general complications. CONCLUSIONS Field tests may be able to predict postoperative outcome; however, further validation is needed. The ISWT appears to be the superior field test. The 6MWT and stair climb test require further validation to assess their predictive ability.
Supportive Care in Cancer | 2018
Ciarán Haberlin; Tom O’Dwyer; David Mockler; Jonathan Moran; Dearbhaile M. O’Donnell; Julie Broderick
PurposeAchieving adequate levels of physical activity (PA) and avoiding sedentary behaviour are particularly important in cancer survivors. eHealth, which includes, but is not limited to, the delivery of health information through Internet and mobile technologies, is an emerging concept in healthcare which may present opportunities to improve PA in cancer survivors. The aim of this systematic review was to explore the effects of eHealth in the promotion of PA among cancer survivors.MethodsSuitable articles were searched using PubMed, CINAHL, EMBASE, PsychInfo, Web of Science and SCOPUS databases using a combination of keywords and medical subject headings. Articles were included if they described an eHealth intervention designed to improve PA in cancer survivors. Two reviewers screened studies for inclusion.ResultsIn total, 1065 articles were considered. Ten studies met eligibility criteria. A variety of platforms designed to increase PA were described in these studies: web application (app) (n = 5), web and mobile application (n = 2), mobile app (n = 1), website only (n = 1), e-mail based (n = 1). All studies measured PA using self-report outcome measures with the exception of one study which measured steps using a Fitbit. Meta-analysis was not performed because of variations in study design and interventions. All studies reported improvements in PA, with 8/10 studies reporting statistically significant changes.ConclusionThe use of eHealth to promote PA in cancer survivors is a relatively new concept, which is supported by the recent emergent evidence described in this review. eHealth shows promise as a means of promoting and increasing daily PA, but further high-quality, longer term studies are needed to establish the feasibility and effectiveness of eHealth platforms aimed at that goal.
Gait & Posture | 2015
Jonathan Moran; Alexandra Murphy; David Murphy; Andy Austin; Danielle Moran; Caitriona Cronin; Emer Guinan; Juliette Hussey
Crutches are commonly prescribed to patients with lower limb dysfunction during rehabilitation to assist with mobility. The aim of this study was to determine the energy expenditure for non-weight bearing crutch walking on level ground and ascending stairs at a self selected speed in a healthy adult population. Thirty-one healthy male and female adults (mean±SD: age 21.6±1.2 years; height 170.8±10.8 cm; weight 70.8±11.4 kg) mobilised non-weight bearing with elbow crutches along a 30 m corridor and (with one crutch) up a flight of 13 stairs. Energy expenditure for each activity was measured by indirect calorimetry using the COSMED K4b(2) portable ergospirometry system. The established VO2 values were 16.4ml/kg/min for crutch walking on level ground and 17.85 ml/kg/min for stair climbing. Non-weight bearing crutch walking at a self selected speed on the level ground and up a flight of stairs resulted in a MET value of 4.57 and 5.06 respectively. The mean heart rate (HR) for crutch walking along the flat was 117.06±20.54 beats per minute (bpm), while the mean HR for ambulating upstairs with crutches was 113.91±19.32 bpm. The increased energy demands of non-weight bearing crutch walking should be considered by physical therapists when instructing patients on crutch use. Further investigation to determine the implications of these results in populations with chronic disease is warranted.
Surgery | 2016
Jonathan Moran; Emer Guinan; Paul McCormick; John Larkin; David Mockler; Juliette Hussey; Jeanne Moriarty; Fiona Wilson
Journal of Physiotherapy | 2017
Tom O’Dwyer; Ann Monaghan; Jonathan Moran; Finbar D O'Shea; Fiona Wilson
Surgery | 2017
Jonathan Moran; Emer Guinan; Paul McCormick; John Larkin; David Mockler; Juliette Hussey; Jeanne Moriarty; Fiona Wilson
Physiotherapy | 2018
Gráinne Kelly; Aoife Reilly; Hannah Moloney; Jonathan Moran; Caitriona Cunningham; Julie Broderick
Mesentery and Peritoneum | 2018
Mary Flahive; James o Driscoll; Joanne Dowd; Dinuk Wijewardene; Brian Moran; Patricia Pond; Louise Coman; Amy Hayes; David Mockler; Jean Saunders; Jonathan Moran; Julie Broderick
Journal of Clinical Oncology | 2018
Ciarán Haberlin; Jonathan Moran; Julie Broderick; Dearbhaile M. O'Donnell