Joost Verhelst
Erasmus University Medical Center
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Featured researches published by Joost Verhelst.
Surgery | 2015
Joost Verhelst; Lucas Timmermans; Maurits van de Velde; An Jairam; Konstantinos A. Vakalopoulos; Johannes Jeekel; Johan F. Lange
BACKGROUND Incisional hernia (IH) is among the most common postoperative complications after abdominal surgery. Operative treatment (OT) using mesh is the treatment of choice. A strategy of watchful waiting (WW) might be a considered in some patients. This retrospective study compares the outcomes of WW and OT. METHODS All patients presenting with IH in an academic surgery department between January 2004 and December 2009 were analyzed according to whether they were treated by WW or OT. Crossovers between both groups were also analyzed. Patient characteristics, information about the initial abdominal operative procedure, symptoms at presentation, and characteristics of the hernia were collected retrospectively. In case of OT, postoperative complications were analyzed. RESULT In total, 255 patients were included; 151 (59%) in the OT group and 104 (41%) in WW group. The median follow-up was 68 months (interquartile range [IQR], 52-93). The reasons for WW were the absence of symptoms in 34 patients (33%), comorbidities in 24 (23%), and obesity in 23 (22%). During follow-up, 34 patients (33%) crossed over from WW to OT. Eight of the crossovers (24%) were emergency repairs owing to incarceration at a median of 1 month (IQR, 1-5) after the start of WW. The incidence of unexpected intraoperative intestinal perforation was greater in the crossover group (13%) compared with the OT group (2%; P = .002). Postoperative fistulas were seen in 7% of patients who crossed over from WW to OT versus 0% in primary OT (P = .002). Postoperatively, 3 patients died, 2 of whom were treated operatively after belonging initially to the WW group. CONCLUSION WW for IH leads to high crossover rates with significantly greater incidence of intraoperative perforations, fistulas, and mortality, than in the OT group, particularly in patients who require emergency repair of IH owing to incarceration.
Surgery | 2016
Liselotte S. Ooms; Joost Verhelst; Johannes Jeekel; Jan N. M. IJzermans; Johan F. Lange; Türkan Terkivatan
BACKGROUND The objective was to evaluate the incidence and treatment of incisional hernia after kidney transplantation and to identify potential risk factors. METHODS A retrospective cohort study was performed. All kidney transplant recipients between 2002 and 2012 were included. Two groups were identified: patients with and without incisional hernia. An analysis of risk factors for the development of incisional hernia was performed. RESULTS A total of 1,564 kidney recipients were included. Fifty patients (3.2%) developed incisional hernia. On univariate analysis, female sex (54 vs 35%), body mass index (BMI) >30 kg/m(2) (38 vs 17%), concurrent abdominal wall hernia (30 vs 16%), multiple explorations of the ipsilateral iliac fossa (38 vs 19%), left iliac fossa implantation (36 vs 24%), history of smoking (72 vs 57%), and duration of the kidney transplantation procedure (210 vs 188 minutes) were associated with the development of incisional hernia (P < .05 each). In multivariate analyses, female sex (hazard ratio [HR] 2.6), history of smoking (HR 2.2), obesity (BMI >30; HR 2.9), multiple explorations of the ipsilateral iliac fossa (HR 2.0), duration of operation (HR 1.007), and concurrent abdominal wall hernia (HR 2.3) were independent risk factors. Twenty-six of 50 patients (52%) underwent operative repair, of whom 9 (35%) required emergency repair. CONCLUSION The incidence of incisional hernia after kidney transplantation with a median follow-up of 59 months is 3.2%. Obesity (BMI >30), female sex, concurrent abdominal wall hernias, history of smoking, duration of surgery, and multiple explorations were independent risk factors for the development of incisional hernia after kidney transplantation. Attempts at preventing incisional hernias based on these risk factors should be explored.
Journal of The American College of Surgeons | 2015
Barry de Goede; Joost Verhelst; Bob J. van Kempen; Martin G. Baartmans; Hester R. Langeveld; Jens A. Halm; Geert Kazemier; Johan F. Lange; Rene Wijnen
BACKGROUND Common surgical knowledge is that inguinal hernia repair in premature infants should be postponed until they reach a certain weight or age. Optimal management, however, is still under debate. The objective of this study was to collect evidence for the optimal management of inguinal hernia repair in premature infants. STUDY DESIGN In the period between 2010 and 2013, data for all premature infants with inguinal hernia who underwent hernia correction within 3 months after birth in the Erasmus MC-Sophia Childrens Hospital, Rotterdam were analyzed. Primary outcomes measures were the incidences of incarceration and subsequent emergency surgery. In a multivariate analysis, Cox proportional hazards model served to identify independent risk factors for incarceration requiring an emergency procedure. RESULTS A total of 142 premature infants were included in the analysis. Median follow-up was 28 months (range 15 to 39 months). Seventy-nine premature infants (55.6%) presented with a symptomatic inguinal hernia; emergency surgery was performed in 55.7%. Complications occurred in 27.3% of emergency operations vs 10.2% after elective repair; recurrences occurred in 13.6% vs 2.0%, respectively. Very low birth weight (≤1,500 g) was an independent risk factor for emergency surgery, with a hazard ratio of 2.7 in the Cox proportional hazards model. CONCLUSIONS More than half of premature infants with an inguinal hernia have incarceration. Those with very low birth weight have a 3-fold greater risk of requiring an emergency procedure than heavier premature infants. Emergency repair results in higher recurrence rates and more complications. Elective hernia repair is recommended, particularly in very low birth weight premature infants.
International Journal of Surgery | 2015
Joost Verhelst; B. de Goede; Gert-Jan Kleinrensink; Johannes Jeekel; Johan F. Lange; K.H.A. van Eeghem
INTRODUCTION The Rives-Stoppa and component separation technique are considered to be favourable techniques in the treatment of complex incisional hernias. However, mesh-related complications like chronic pain are still a common problem after mesh repair. As a result, a new self-gripping mesh to omit suture fixation has been developed. This study aimed to evaluate the safety and feasibility of the Parietex™ Progrip self-gripping mesh in retromuscular position for the treatment of incisional hernias. METHODS Patients with incisional hernia who underwent repair between June 2012 and June 2014, using a self-gripping mesh in retromuscular position, were included in the study. All patients visited the outpatient clinic to identify postoperative complications and early recurrence. RESULTS A total of 28 consecutive patients with a median age of 48 years were included in the study. Twenty-two patients (79%) were diagnosed with an incisional hernia, of whom nine (32%) had a recurrence. Six patients (21%) had an incisional hernia combined with another abdominal wall hernia. The median follow-up was 12 weeks (IQR: 8-20 weeks). Twenty-three patients (82%) did not report any pain at their final outpatient clinic visit; two patients (7%) reported mild abdominal pain, and three patients (11%) had moderate abdominal pain. None of the 28 patients developed a recurrence during follow-up. CONCLUSION This is the first study concerning the use of a Parietex™ Progrip mesh placed in retromuscular position. The study shows that it is a safe and feasible prosthesis in incisional hernias repair, as short-term recurrence did not occur and adverse events were limited.
International Journal of Surgery Case Reports | 2016
Eva B. Deerenberg; Joost Verhelst; Steven E.R. Hovius; Johan F. Lange
Highlights • Swelling of the abdominal wall after abdominal wall reconstruction can be caused by a recurrence or bulging of the mesh.• CT-scan can be useful to distinguish between a true recurrence or bulging of the mesh.• Bulging of a mesh can be caused by pore enlargement and expansion of the mesh.• The distinction between a recurrence and bulging of the mesh is therapeutically irrelevant in symptomatic patients.• Mesh characteristics should be considered when choosing a feasible and suitable mesh for abdominal wall reconstruction.
International Journal of Surgery | 2017
Leonard F. Kroese; Lien H.A. van Eeghem; Joost Verhelst; Johannes Jeekel; Gert-Jan Kleinrensink; Johan F. Lange
BACKGROUND In case of complex ventral hernias, Rives-Stoppa and component separation technique are considered as favourable treatment techniques. However, mesh-related complications like recurrence, infection and chronic pain are still a common problem after mesh repair. Previous studies have reported promising results of the use of a self-gripping mesh (ProGrip™) in incisional hernia repair. This study aimed to evaluate the long term results of this mesh for complex ventral hernia treatment. MATERIALS AND METHODS Patients with complex ventral hernia undergoing repair between June 2012 and June 2015, using the ProGrip™-mesh in retromuscular position, were included. All patients visited the outpatient clinic to evaluate short term complications and recurrence. After at least one year, telephone interviews were conducted to evaluate long term results. RESULTS A total of 46 patients (median age 59 years) were included. 40 patients (87%) were diagnosed with incisional hernia. Seven patients (18%) had incisional hernia combined with another hernia. Four patients (8.7%) had an umbilical hernia, one patient (2.2%) had an epigastric hernia and one patient (2.2%) had rectus diastasis. 39 patients completed follow-up. Median follow-up was 25 months (IQR: 19-35 months). 28 patients (72%) did not report any complaints. Nine patients reported pain (average VAS of 1.7). Two patients developed a recurrence requiring reoperation. One patient developed mesh infection requiring reoperation. CONCLUSION Long term results of the use of a self-gripping mesh for complex abdominal wall hernias show a low recurrence rate, even in complex hernia cases. This makes the mesh a good choice in this difficult patient group.
Hernia | 2015
G. Kenchadze; I. Pipia; Z. Demetrashvili; A. Botezatu; E. Marakutsa; R. Raileanu; V. Trischuk; N. Elzakaky; E. Elkayal; A. Shawky; A. Elgendi; A. Espinosa-De-Los-Monteros; L. Arista-De La Torre; H. Avendaño-Peza; D. Zamora-Valdes; Z. Gomez-Arcive; A. Elnecave-Olaiz; Y. Yap; H. J. Lee; V. Nallathamby; W. C. Ong; J. Lim; T. C. Lim; Raymond Dunn; S. Figy; A. Shkreta; A. Karam; M. Cahan; E. Shepetko; P. Fomin
Methods: A retrospective review of patients with large midline abdominal hernia treated using component separation technique from 2009 to 2013 at General Surgery Department of Kipshidze Central University Hospital was performed. The scoring criteria were wound complications (infection, hematoma, seroma, scin necrosis, secondary healing), time to return to work/normal activities and recurrent hernia. The mean follow-up time was 21 months.
Hernia | 2017
Leonard F. Kroese; Jj Harlaar; C. Ordrenneau; Joost Verhelst; G. Guérin; F. Turquier; Richard Goossens; Gert-Jan Kleinrensink; Johannes Jeekel; Johan F. Lange
Trials | 2018
Anne Loes van den Boom; Elisabeth M. L. de Wijkerslooth; Joost van Rosmalen; Frédérique H. Beverdam; Evert-Jan G. Boerma; Marja A. Boermeester; Joanna W. A. M. Bosmans; Thijs A. Burghgraef; Esther C. J. Consten; Imro Dawson; Jan Willem T. Dekker; Marloes Emous; Anna A. W. van Geloven; P. M. N. Y. H. Go; Luc A. Heijnen; Sander A. Huisman; Dayanara Jean Pierre; Joske de Jonge; Jurian H. Kloeze; Marc A. Koopmanschap; Hester R. Langeveld; Misha D. Luyer; Damian C. Melles; Johan W. Mouton; Augustinus P. T. van der Ploeg; Floris B. Poelmann; Jeroen E. H. Ponten; Charles C. van Rossem; Wilhelmina H. Schreurs; Joel Shapiro
Hernia | 2016
Joost Verhelst; B. de Goede; B. J. H. van Kempen; Hester R. Langeveld; M. J. Poley; Geert Kazemier; J. Jeekel; Rene Wijnen; Johan F. Lange