Jorge Mitre

Intravitreal gas injection for the treatment of experimental vitreous hemorrhage in rabbits.

Purpose. To determine the effectiveness of intravitreous gas injection in the management and clearing of experimental vitreous hemorrhage. Methods. A total of ten New Zealand white rabbits received an injection of 0.4 ml of autologous blood into the vitreous of the right eye. After 24 hours of the vitreous hemorrhage simulation, six eyes were randomly assigned for treatment with na intravitreous injection of 0.2 ml of 100% perfluoropropane gas (C3F8) (group A), while four eyes received a control injection of an equivalent volume of balanced salt solution (group B). The persistence of vitreous opacification, which was graded at pre-established time points during 32 days of follow-up, was evaluated on the basis of visibility of retinal details in each of the four quadrants. Results. In the gas-treated group (A), a partial view of the retina in the four quadrants was possible at 15 days, while at 32 days, the vitreous cavity was completely free of blood in all eyes, allowing unobstructed observation of the fundus. No retinal details could be observed in the control group after 32 days of follow-up. Conclusions. Gas injection proved effective in the treatment of experimental vitreous hemorrhage. It was significantly better than the injection of balanced salt solution, according to criteria of extension, intensity, and clearing time. Its technical facility, lack of complications, and low cost encourage additional research into gas injection to add knowledge to this initial study and to clarify its potential usefulness to treat persistent vitreous hemorrhage as well as to elucidate some unique pathophysiology features of blood catabolism in the vitreous.

Pachychoroid, an update from the new finding to the usual investigation in selected diseases

The authors make an update of pachychoroid in a group of the choroidal-retinal diseases that choroidal thickening is an usualenhanced depth image - optic coherence tomography (EDI-OCT) finding like as central serous chorioretinopathy, pachychoroid neovasculopathy, polipoidal choroidal vasculopathy and pachychoroid pigment epitheliopathy.

Drusen-like beneath retinal deposits in type II mesangiocapillary glomerulonephritis: a review

The aim of this paper is to do a review of Drusen-like beneath retinal deposits in type II mesangiocapillary glomerulonephritis. Drusenlike beneath retinal deposits in type II mesangiocapillary glomerulonephritis appear to develop at an early age, often second decade of life different of drusen from age-related macular degeneration (AMD).Long term follow-up of the cases in this disease shows in the most of them, no progression of the of drusen-like beneath retinal deposits in type II mesangiocapillary glomerulonefritis, the most of subjects retain good visual acuity and no specific treatment is indicated.

Análise da relação entre espessura macular e espessura da camada de fibras nervosas

OBJECTIVE: The objective of this work is to evaluate by means of the OCT Stratus the relation of the macular thickness with the thickness of nervous fiber layers. METHODS: In this work 106 eyes of the service of ophthalmology of the College of Medicine of the ABC had been analyzed. The study included 55 eyes that inside presented values of CFNR or above of the normal values in all the four quadrants and 51 eyes presenting values in only one or more quadrants that suspicion indicates or is of the limit of normality of the values of CFNR, comparing with macular thickness. RESULTS: This study it showed a reduction of the macular thickness in the patients who presented suspicion or reduction of the thickness of CFNR. CONCLUSION: The work demonstrated that the macular thickness can be a weapon important to evaluate a possible loss of nervous fiber layer.

Hemorragia de disco óptico possivelmente secundária a descolamento espontâneo do vítreo posterior

To describe the diagnosis and management of a optic disc haemorrhage probably caused by an acute and spontaneous posterior vitreous detachment. A single case-report of an optic disc haemorrhage probably caused by an spontaneous posterior vitreous detachment, in order to discuss the diagnosis, management and prognosis. Optic disc haemorrhage regression was observed after 6 hours of evolution without relapsing signals during the subsequent registers. The Scanning Laser Ophthalmoscopy revealed as an advanced alternative and efficient method in the vitreous detachment diagnosis and follow up.