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Dive into the research topics where Jørgen Nepper-Rasmussen is active.

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Featured researches published by Jørgen Nepper-Rasmussen.


Acta Oto-laryngologica | 2005

Selective embolization in the treatment of intractable epistaxis

Pia Juul Andersen; Anette Drøhse Kjeldsen; Jørgen Nepper-Rasmussen

Conclusions. In skilled hands, selective embolization is a safe procedure and represents an effective treatment for prolonged epistaxis. Embolization therapy can be repeated if necessary. Objective. Severe posterior epistaxis is a common clinical problem in an ENT department and controlling the bleeding may present difficulties. Several methods are used to control posterior epistaxis, one of the latest treatment strategies being selective embolization of the nasal arteries. The aim of this study was to describe the effect of selective embolization in 22 patients treated with a total of 30 procedures at the ENT Department of Odense University Hospital between January 1995 and March 2004. To our knowledge this is the first Nordic work in which selective embolization has been used as a treatment strategy for patients with hereditary hemorrhagic telangiectasia (HHT). Material and methods. This was a retrospective review. Post-treatment effects and complications were evaluated by means of a questionnaire and a telephone interview. Owing to the different treatment strategies used, the results were evaluated for 2 groups of patients: Group A, 9 patients with HHT; and Group B, 13 patients with causes of epistaxis other than HHT. Results. In Group A, 15 procedures were performed, 12 of which were beneficial as the duration and number of episodes of epistaxis were reduced. In Group B, 15 procedures were performed and the success rate was 87%. One patient suffered from skin necrosis at the tip of the nose. No other serious side-effects of the treatment were observed.


Interventional Neuroradiology | 2011

Endovascular treatment of very small intracranial aneurysms.

A. Iskandar; Jørgen Nepper-Rasmussen

The endovascular treatment of intracranial aneurysms 3 mm or less is considered controversial. The purpose of this study is to report angiographic and clinical results following coiling of such aneurysms and compare them to those of larger aneurysms (> 3 mm). Between November 1999 and November 2009 endovascular treatment was attempted in 956 consecutive intracranial aneurysms. Of 956 aneurysms, 111 aneurysms were very small aneurysms with a maximal diameter of 3 mm or less. We conducted a retrospective analysis of angiographic and clinical outcome following coiling of very small aneurysms and subsequently comparing it to the results of larger aneurysms. Coiling initially failed in eight aneurysms. In the remaining 103 aneurysms endovascular treatment was accomplished and immediate angiographic results showed complete aneurysm occlusion in 43 aneurysms, nearly complete aneurysm occlusion in 54 aneurysms and less than 90% aneurysm occlusion in six aneurysms. Complications occurred in the treatment of 15 aneurysms, including eight procedural ruptures, six thromboembolic events and one case of early hemorrhage. Compared with larger aneurysms, treatment of very small aneurysms was associated with a higher rate of procedural ruptures (7.2% versus 4.4%) and procedural mortality (4.7% versus 2.7%) but a lower procedural morbidity (1.9% versus 4.0%). However none of these differences reached statistical significance (p = 0.186, p= 0.388, respectively). The retreatment rate was higher for the larger aneurysms (8.2% and 6.3%), but this was not significant either (p= 0. 496). At nine-month follow-up significantly more small aneurysms were found to have a stable occlusion grade compared to large aneurysms. Endovascular treatment of very small aneurysms is feasible with a lower retreatment rate compared to large aneurysms (> 3 mm). However the data also suggest that endovascular treatment of very small aneurysms might be associated with an increased risk of procedural ruptures and mortality. At nine-month follow-up results indicate significantly less compaction in the very small aneurysms.


Acta Neurologica Scandinavica | 2009

Cerebral infarct following carotid endarterectomy. Frequency, clinical and hemodynamic significance evaluated by MRI and TCD.

E. M. Enevoldsen; T. Torfing; M. J. Kjeldsen; Jørgen Nepper-Rasmussen

The purpose of this study was to disclose the frequency of new infarcts after Carotid Endarterectomy (CEA) by MRI and Transcranial Doppler examinations (TCD), and to evaluate the clinical and pathological significance. Of a consecutive series of 41 patients with a symptomatic carotid stenosis exceeding 69%, 33 had MRI and TCD examinations performed before and after the CEA. Pre‐operative MRIs revealed Focal High Signal Intensity (FHSI) in 21 patients (64%) on the side of the stenosis, ranging in number from 2 to more than 20 and in size from 0.5 cm to more than 3 cm. After the operation 8 patients (24%) each had acquired from 1‐4 new FHSIs, but only 3 patients (9%) suffered from clinical symptoms. In 2 patients, who had had a stroke, the FHSIs were more than 3 cm. In 1 patient, who experienced a Transient Ischemic Attack (TIA), the FHSI was 1‐2 cm. The TCD disclosed low Pulsatility Index (PI) values in 2 of the 3 patients who had new FHSIs and clinical symptoms. In all the patients who did not show new FHSIs after the operation, the PI was normal in the MCA of the symptomatic hemisphere after CEA. So new cerebral FHSIs were rather frequent after a CEA, but only FHSIs >1 cm were accompanied by a TIA or stroke, and a low PI in the MCA of the relevant hemisphere was found before or in connection with the operation in 2 of the 3 patients who developed clinical symptoms.


Interventional Neuroradiology | 1998

Aneurysm on a persisting primitive trigeminal artery occluded with guglielmi detachable coils.

Jørgen Nepper-Rasmussen; Bjerre P; Andersen P

A persisting primitive trigeminal artery (PPTA) is present in 0.2 – 0.6% of all cerebral angiographies. 27 cases of PPTA aneurysms have been reported. We present a case with sixth cranial nerve palsy due to a non ruptured aneurysm on a persisting primitive trigeminal artery. The aneurysm was successfully occluded with Guglielmi Detachable Coils with preservation of the parent artery. The cranial nerve palsy resolved and recovery was uneventful.


Ugeskrift for Læger | 2015

Diagnose og behandling af cerebral venøs sinustrombose

Peter Birkeland; Stilling Mv; Lisbeth Høgedal; Mette Katrine Schulz; Jørgen Nepper-Rasmussen; Frantz Rom


Ugeskrift for Læger | 2015

Diagnosis and treatment of cerebral venous sinus thrombosis

Peter Birkeland; Stilling Mv; Lisbeth Høgedal; Mette Katrine Schulz; Jørgen Nepper-Rasmussen; Rom F


Ugeskrift for Læger | 2013

Henvisningskriterier til hjernekræft pakkeforløb kun moderat associeret til magnetisk resonansscanningsfund

Tw Hill; Mk Nielsen; Jørgen Nepper-Rasmussen


Danish Medical Journal | 2013

Admission criteria to the Danish Brain Cancer Program are moderately associated with magnetic resonance imaging findings.

Thomas Winther Hill; Mie Kiszka Nielsen; Jørgen Nepper-Rasmussen


Ugeskrift for Læger | 2009

Local thrombolysis of sinus thrombosis

Soll Nh; Karsten Vestergård; Jørgen Nepper-Rasmussen


Ugeskrift for Læger | 2009

Lokal trombolyse af sinustrombose

Nicolai Højmose Soll; Karsten Vestergård; Jørgen Nepper-Rasmussen

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John Jakobsen

Copenhagen University Hospital

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Lisbeth Høgedal

Odense University Hospital

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Peter Birkeland

Odense University Hospital

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Pia Juul Andersen

Odense University Hospital

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