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Dive into the research topics where José-Alain Sahel is active.

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Featured researches published by José-Alain Sahel.


Archive | 2018

Retinal Prostheses: Other Therapies and Future Directions

Olivier Goureau; Christelle Monville; Antoine Chaffiol; Gregory Gauvain; Serge Picaud; Jens Duebel; José-Alain Sahel

Inherited and age-related retinal dystrophies, such as retinitis pigmentosa (RP) and age-related macular degeneration (AMD), respectively, are a leading cause of irreversible vision loss. Various approaches aiming at restoring visual function in the blind are currently under development and evaluation: neuroprotection, gene and cell therapy, and retinal prostheses. In this review, we focus on recent advances in optogenetics and cell therapy, two therapeutic strategies that have the potential to restore vision in a broad spectrum of retinal degenerative diseases. We discuss major advantages of optogenetics and cell therapies as well as their current limitations.


Archive | 2002

Disease-associated protein

Thierry Leveillard; José-Alain Sahel; Saddek Mohand-Said; David Hicks


Archive | 2012

Disease-associated proteins

Thirry Léveillard; José-Alain Sahel; Saddek Mohand-Said; Olivier Poch; David Hicks; Carlos Alvarez


Archive | 2018

CELLULES PRÉCURSEURS DE PHOTORÉCEPTEURS OPTOGÉNÉTIQUEMENT TRANSFORMÉES DESTINÉES À ÊTRE UTILISÉES DANS LE TRAITEMENT DES MALADIES DÉGÉNÉRATIVES DE LA RÉTINE

Jens Duebel; Marius Ader; Antoine Chaffiol; Marcela Garita-Hernandez; Maruša Lampič; Deniz Dalkara; Olivier Goureau; José-Alain Sahel


Archive | 2017

método para determinar a configuração de um filtro oftálmico

Coralie Barrau; Denis Cohen-Tannoudji; Emilie Arnault; José-Alain Sahel; Serge Picaud; Thierry Villette


Archive | 2016

PROMOTERS AND USES THEREOF

Deniz Dalkara; Serge Picaud; Mélissa Desrosiers; José-Alain Sahel; Jens Duebel; Alexis Bemelmans; Botond Roska


Archive | 2015

Cellules transgéniques de l'épithélium pigmentaire rétinien (rpe) surexprimant le gène otx2 pour le traitement de la dégénérescence rétinienne

Thierry Leveillard; Christo Kole; José-Alain Sahel


Archive | 2015

« Rod-derived cone viability factor : un espoir de thérapie des dégénérescences rétiniennes ? / Rod-derived cone viability factor : a clue for therapy of retinitis pigmentosa? »

Thierry Leveillard; Saddek Mohand-Said; José-Alain Sahel


Archive | 2015

Gene Therapy for Vision Disorders

Deniz Dalkara; José-Alain Sahel


Archive | 2015

novel branch of the thioredoxin fold superfamily The evolutionarily conserved Dim1 protein defines a

Hong Cheng; Heinrich Roder; Erica A. Golemis; Yuzhu Zhang; Kathleen L. Gould; Roland L. Dunbrack; Xiaojing Sun; Hua Zhang; Dan Wang; Dalong Ma; Yan Shen; Yongfeng Shang; Alain Van Dorsselaer; José-Alain Sahel; Thierry Leveillard; Ludivine Perrocheau; Géraldine Millet-Puel; Marie-Laure Niepon; Olivier Poch; Arne Holmgren; Ram Fridlich; François Delalande; Céline Jaillard; Jun Lu; Laetitia Poidevin; Therese Cronin

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Jens Duebel

Friedrich Miescher Institute for Biomedical Research

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Saddek Mohand-Said

French Institute of Health and Medical Research

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Botond Roska

National Chiao Tung University

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