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Jose Alexander

University of Kansas

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Publication

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Tetrahedron Letters | 1981

Regiospecific synthesis of 11-desoxyanthracycline antibiotics starting with aloe-emodin

Jose Alexander; D.L. Flynn; Lester A. Mitscher; Tarik Veysoglu

Abstract The regiospecific synthesis of an established 11-desoxyanthracycline synthon ( 8b ) from aloe-emodin ( 3a ) is described.

Journal of Medicinal Chemistry | 1988

(Acyloxy)alkyl carbamates as novel bioreversible prodrugs for amines: increased permeation through biological membranes

Jose Alexander; Robyn Cargill; Stuart R. Michelson; Harvey Schwam

Journal of Medicinal Chemistry | 1996

Investigation of (Oxodioxolenyl)methyl Carbamates as Nonchiral Bioreversible Prodrug Moieties for Chiral Amines

Jose Alexander; Dilbir S. Bindra; Joan D. Glass; Marie A. Holahan; Mara L. Renyer; Gerald S. Rork; Gary R. Sitko; Maria T. Stranieri; Raymond F. Stupienski; Hemalata Veerapanane; Jacquelynn J. Cook

Journal of Organic Chemistry | 1980

Methylation and hydroxylation studies on aloe-emodin

Jose Alexander; Ashok V. Bhatia; Lester A. Mitscher; Shoji Omoto; Toshio Suzuki

Journal of Organic Chemistry | 1980

Novel ring hydroxylation of aloe emodin and further elaboration to anthracycline synthons

Jose Alexander; Ashok V. Bhatia; George W. Clark; Arthur Leutzow; Lester A. Mitscher; Shoji Omoto; Toshio Suzuki

Journal of Medicinal Chemistry | 1984

Total chemical synthesis and antitumor evaluation of 4-demethoxy-10,10-dimethyldaunomycin

Jose Alexander; Ish Khanna; Daniel Lednicer; Lester A. Mitscher; Tarik Veysoglu; Zbigniew Wielogorski; Richard L. Wolgemuth

Tetrahedron Letters | 1978

A short, efficient synthesis of an anthracycline antitumor antibiotic synthon

Jose Alexander; Lester A. Mitscher

Archive | 1980

Synthesis of 2-hydroxy-2-acetyl-1,2,3,4-tetrahydronaphthalene compounds.

Jose Alexander; Lester A. Mitscher

Archive | 1979

5,12-dihydroxy-1,2,3,4,6,11-hexahydro-2,6,11-trioxonaphthacenes and their synthesis

Jose Alexander; Lester A. Mitscher

Journal of Organic Chemistry | 1984

Reaction of formaldehyde with nucleosides: addition to 2',3',5'-triacetyl 9-.beta.-D-arabinofuranosyladenine

Jose Alexander

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Lester A. Mitscher

University of Kansas

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Ashok V. Bhatia

University of Kansas

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L. A. Mitscher

Ohio State University

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Toshio Suzuki

Niigata University

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Tarik Veysoglu

University of Kansas

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D.L. Flynn

University of Kansas

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Dilbir S. Bindra

Merck

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Gary R. Sitko

Merck

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George W. Clark

Ohio State University

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Gerald S. Rork

Merck

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