Network


Latest external collaboration on country level. Dive into details by clicking on the dots.

Hotspot


Dive into the research topics where José Nunes da Silva Júnior is active.

Publication


Featured researches published by José Nunes da Silva Júnior.


Journal of the Brazilian Chemical Society | 2015

Biotransformation of the Diterpene Ent-18,19-dihydroxytrachylobane by Rhizopus stolonifer

Daniely H. P. Vasconcelos; Jair Mafezoli; Paula Karina S. Uchoa; Natália N. Saraiva; Mary Anne S. Lima; José Nunes da Silva Júnior; Francisco Geraldo Barbosa; Marcos Carlos de Mattos; Maria da Conceição F. de Oliveira; Cristiano Souza Lima; Maria Nenmaura Gomes Pessoa

The diterpene ent-18,19-dihydroxytrachylobane was biotransformed for the first time by Rhizopus stolonifer, and yielded the new ent-11β,18,19-trihydroxytrachylobane derivative besides the new ent-kaur-11-ene diterpenes ent-16α,18,19-trihydroxykaur-11-ene and ent-18,19-dihydroxy-16α-methoxykaur-11-ene. Their structures were determined by spectrometric methods.


Journal of the Brazilian Chemical Society | 2015

New Terpenoids from Croton limae (Euphorbiaceae)

Sousa Ah; José Nunes da Silva Júnior; Maria Lenise Silva Guedes; Raimundo Braz-Filho; Letícia V. Costa-Lotufo; Ana Jérsia Araújo; Edilberto R. Silveira; Mary Anne S. Lima

An asymmetrical dimer of kaurane diterpene and monoterpene and four novel diterpenes were isolated from the roots of Croton limae, along with kaempferol-3-O-glucoside, ombuin- 3-O-rutinoside and acetyl aleuritolic acid. The cytotoxic activity of the kaurane diterpene was evaluated against colorectal adenocarcinoma (HCT-116), ovarian carcinoma (OVCAR-8) and glioma (SF-295) cell lines, exhibiting IC50 values of 7.14, 8.19 and > 10 µg mL−1, respectively.


Química Nova | 2014

Ressonância: desenvolvimento, utilização e avaliação de um software educacional

José Nunes da Silva Júnior; Francisco Geraldo Barbosa; Antonio José Melo Leite Junior; Valeska Mesquita Eduardo

that shows how electrons are shared between two or more atoms and allows a prediction of the chemical reactivity and relative stability of reagents, intermediates, and products. An educational software that enables interactive exploration of the concepts related to resonance and thereby facilitates its understanding was developed. The software was field-tested, and an evaluation questionnaire concerning the software as an educational tool was answered by the students and professors involved in the test. The results led to the conclusion that the developed computer application can be characterized as an auxiliary tool that assists teachers in their lectures and students in their learning process.


Química Nova | 2012

Polarímetro virtual: desenvolvimento, utilização e avaliação de um software educacional

José Nunes da Silva Júnior; Francisco Geraldo Barbosa; Antonio José Melo Leite Junior

Optical activity is the ability of chiral substances to rotate the plane of plane-polarized light and is measured using an instrument called a polarimeter. An educational software application to explore, both interactively and visually, the concepts related to polarimetry to facilitate their understanding was developed. The software was field-tested and a questionnaire evaluating the graphics interface, usability and the software as an educational tool, was answered by students. The results characterized the computer application developed as an auxiliary tool for assisting teachers in lectures and students in the learning process.


Química Nova | 2015

INTERACTIONS: DESIGN, IMPLEMENTATION AND EVALUATION OF A COMPUTATIONAL TOOL FOR TEACHING INTERMOLECULAR FORCES IN HIGHER EDUCATION

Francisco Geraldo Barbosa; Jair Mafezoli; Mary Anne S. Lima; Francisco Serra Oliveira Alexandre; Diego Macedo de Almeida; Antonio José Melo Leite Junior; José Nunes da Silva Júnior

Intermolecular forces are a useful concept that can explain the attraction between particulate matter as well as numerous phenomena in our lives such as viscosity, solubility, drug interactions, and dyeing of fibers. However, studies show that students have difficulty understanding this important concept, which has led us to develop a free educational software in English and Portuguese. The software can be used interactively by teachers and students, thus facilitating better understanding. Professors and students, both graduate and undergraduate, were questioned about the software quality and its intuitiveness of use, facility of navigation, and pedagogical application using a Likert scale. The results led to the conclusion that the developed computer application can be characterized as an auxiliary tool to assist teachers in their lectures and students in their learning process of intermolecular forces.


Helvetica Chimica Acta | 2013

Crotofolane‐ and Casbane‐Type Diterpenes from Croton argyrophyllus

Francisco Artur e Silva Filho; José Nunes da Silva Júnior; Raimundo Braz-Filho; Carlos A. de Simone; Edilberto R. Silveira; Mary Anne S. Lima


Journal of Chemical Education | 2014

KinChem: A Computational Resource for Teaching and Learning Chemical Kinetics

José Nunes da Silva Júnior; Mary Anne S. Lima; Eduardo Henrique Silva Sousa; Francisco Serra Oliveira Alexandre; Antonio José Melo Leite Junior


Journal of Chemical Education | 2017

Stereogame: An Interactive Computer Game That Engages Students in Reviewing Stereochemistry Concepts

José Nunes da Silva Júnior; Mary Anne S. Lima; João Victor Xerez Moreira; Francisco Serra Oliveira Alexandre; Diego Macedo de Almeida; Maria da Conceição F. de Oliveira; Antonio José Melo Leite Junior


Natural Product Communications | 2014

Stereo and regioselective microbial reduction of the clerodane diterpene 3,12-dioxo-15,16-epoxy-4-hydroxycleroda-13(16),14-diene.

Mafezoli J; Oliveira Mc; Paiva; Sousa Ah; Lima Ma; José Nunes da Silva Júnior; Francisco Geraldo Barbosa; Wijeratne Em; Gunatilaka Aa


Journal of the Brazilian Chemical Society | 2012

New flavonoids and coumarins from Platymiscium floribundum Vogel

Pérsio Alexandrino Veloso; Antonia T. A. Pimenta; Sousa Francisco M. de; Maria José C. Falcão; Nilce V. Gramosa; José Nunes da Silva Júnior; Edilberto R. Silveira; Mary Anne S. Lima

Collaboration


Dive into the José Nunes da Silva Júnior's collaboration.

Top Co-Authors

Avatar

Mary Anne S. Lima

Federal University of Ceará

View shared research outputs
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar

Jair Mafezoli

Federal University of Ceará

View shared research outputs
Top Co-Authors

Avatar
Top Co-Authors

Avatar

Davi Janô Nobre

Federal University of Ceará

View shared research outputs
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Researchain Logo
Decentralizing Knowledge