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Dive into the research topics where Josefine Metzkes is active.

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Featured researches published by Josefine Metzkes.


New Journal of Physics | 2010

The scaling of proton energies in ultrashort pulse laser plasma acceleration

K. Zeil; S. D. Kraft; S. Bock; M. Bussmann; T. E. Cowan; T. Kluge; Josefine Metzkes; T. Richter; R. Sauerbrey; U. Schramm

This paper presents a systematic investigation of an ultrashort pulse laser acceleration of protons that yields unprecedented maximum proton energies of 17MeV at a table-top Ti:sapphire laser power level of 100TW. For plain few- micron-thick foil targets, a linear scaling of the maximum proton energy with laser power is observed and this is attributed to the short acceleration period close to the target rear surface. Although excellent laser pulse contrast was available, slight deformations of the target rear were found to lead to a predictable shift of the direction of the energetic proton emission away from the target normal that could be used for better discrimination of the low-energy part of the spectrum.


New Journal of Physics | 2010

Dose-dependent biological damage of tumour cells by laser-accelerated proton beams

S. D. Kraft; C. Richter; K. Zeil; Michael Baumann; Elke Beyreuther; S. Bock; M. Bussmann; T. E. Cowan; Y Dammene; W. Enghardt; U. Helbig; L. Karsch; T. Kluge; L. Laschinsky; E Lessmann; Josefine Metzkes; D. Naumburger; R. Sauerbrey; M. Schürer; M. Sobiella; J Woithe; U. Schramm; Jörg Pawelke

We report on the first irradiation of in vitro tumour cells with laser-accelerated proton pulses showing dose-dependent biological damage. This experiment, paving the way for future radiobiological studies with laser-accelerated protons, demonstrates the simultaneous availability of all the components indispensable for systematic radiobiological studies: a laser-plasma accelerator providing proton spectra with maximum energy exceeding 15MeV and applicable doses of a few Gy within a few minutes; a beam transport and filtering system; an in-air irradiation site; and a dosimetry system providing both online dose monitoring and absolute dose information applied to the cell sample and the full infrastructure for analysing radiation-induced damage in cells.


Physics in Medicine and Biology | 2011

A dosimetric system for quantitative cell irradiation experiments with laser-accelerated protons

Christian Richter; L. Karsch; Y Dammene; S. D. Kraft; Josefine Metzkes; U. Schramm; M. Schürer; M. Sobiella; A Weber; K. Zeil; Jörg Pawelke

An integrated dosimetry and cell irradiation system (IDOCIS) with laser-accelerated proton beams was developed, characterized, calibrated and successfully used for systematic in vitro experiments. Due to the broad exponentially shaped energy spectrum, the low-energy range of the protons (<20 MeV) and the high pulse dose, the absolute dosimetry for this beam quality is challenging. Therefore, a dedicated Faraday cup is used as an energy and dose rate independent absolute dosimeter that has been calibrated consistently with three independent methods. A transmission ionization chamber providing online relative dose information is cross-calibrated against the Faraday cup. Providing both online and absolute dose information, the IDOCIS allows for quantitative dosimetric and radiobiological studies at current low-energy laser-accelerated proton beams. Finally, first dosimetric characterizations of a laser-accelerated proton beam with the IDOCIS are presented.


Nature Communications | 2012

Direct observation of prompt pre-thermal laser ion sheath acceleration

K. Zeil; Josefine Metzkes; T. Kluge; M. Bussmann; T. E. Cowan; S. D. Kraft; R. Sauerbrey; U. Schramm

High-intensity laser plasma-based ion accelerators provide unsurpassed field gradients in the megavolt-per-micrometer range. They represent promising candidates for next-generation applications such as ion beam cancer therapy in compact facilities. The weak scaling of maximum ion energies with the square-root of the laser intensity, established for large sub-picosecond class laser systems, motivates the search for more efficient acceleration processes. Here we demonstrate that for ultrashort (pulse duration ~30 fs) highly relativistic (intensity ~1021 W cm−2) laser pulses, the intra-pulse phase of the proton acceleration process becomes relevant, yielding maximum energies of around 20 MeV. Prominent non-target-normal emission of energetic protons, reflecting an engineered asymmetry in the field distribution of promptly accelerated electrons, is used to identify this pre-thermal phase of the acceleration. The relevant timescale reveals the underlying physics leading to the near-linear intensity scaling observed for 100 TW class table-top laser systems.


Physics of Plasmas | 2014

Using X-ray free-electron lasers for probing of complex interaction dynamics of ultra-intense lasers with solid matter

T. Kluge; C. Gutt; Lingen Huang; Josefine Metzkes; U. Schramm; M. Bussmann; T. E. Cowan

We demonstrate the potential of X-ray free-electron lasers (XFEL) to advance the understanding of complex plasma dynamics by allowing for the first time nanometer and femtosecond resolution at the same time in plasma diagnostics. Plasma phenomena on such short timescales are of high relevance for many fields of physics, in particular in the ultra-intense ultra-short laser interaction with matter. Highly relevant yet only partially understood phenomena become directly accessible in experiment. These include relativistic laser absorption at solid targets, creation of energetic electrons and electron transport in warm dense matter, including the seeding and development of surface and beam instabilities, ambipolar expansion, shock formation, and dynamics at the surfaces or at buried layers. In this paper, we focus on XFEL plasma probing for high power laser matter interactions based on quantitative calculations using synthesized data and evaluate the feasibility of various imaging and scattering techniques with special focus on the small angle X-ray scattering technique.


Physical Review Letters | 2017

Relativistic Electron Streaming Instabilities Modulate Proton Beams Accelerated in Laser-Plasma Interactions

S. Göde; Christian Rödel; K. Zeil; Rohini Mishra; Maxence Gauthier; Florian-Emanuel Brack; T. Kluge; Michael MacDonald; Josefine Metzkes; Lieselotte Obst; Martin Rehwald; C. Ruyer; H.-P. Schlenvoigt; W. Schumaker; P. Sommer; T. E. Cowan; U. Schramm; S. H. Glenzer; F. Fiuza

We report experimental evidence that multi-MeV protons accelerated in relativistic laser-plasma interactions are modulated by strong filamentary electromagnetic fields. Modulations are observed when a preplasma is developed on the rear side of a μm-scale solid-density hydrogen target. Under such conditions, electromagnetic fields are amplified by the relativistic electron Weibel instability and are maximized at the critical density region of the target. The analysis of the spatial profile of the protons indicates the generation of B>10  MG and E>0.1  MV/μm fields with a μm-scale wavelength. These results are in good agreement with three-dimensional particle-in-cell simulations and analytical estimates, which further confirm that this process is dominant for different target materials provided that a preplasma is formed on the rear side with scale length ≳0.13λ_{0}sqrt[a_{0}]. These findings impose important constraints on the preplasma levels required for high-quality proton acceleration for multipurpose applications.


Scientific Reports | 2017

Efficient laser-driven proton acceleration from cylindrical and planar cryogenic hydrogen jets

Lieselotte Obst; S. Göde; Martin Rehwald; Florian Emanuel Brack; Joao Branco; S. Bock; M. Bussmann; T. E. Cowan; Chandra Curry; F. Fiuza; Maxence Gauthier; Rene Gebhardt; U. Helbig; Axel Huebl; Uwe Hübner; A. Irman; Lev Kazak; J. B. Kim; T. Kluge; S. D. Kraft; Markus Loeser; Josefine Metzkes; Rohini Mishra; Christian Rodel; Hans Peter Schlenvoigt; Mathias Siebold; J. Tiggesbäumker; Steffen Wolter; Tim Ziegler; U. Schramm

We report on recent experimental results deploying a continuous cryogenic hydrogen jet as a debris-free, renewable laser-driven source of pure proton beams generated at the 150 TW ultrashort pulse laser Draco. Efficient proton acceleration reaching cut-off energies of up to 20 MeV with particle numbers exceeding 109 particles per MeV per steradian is demonstrated, showing for the first time that the acceleration performance is comparable to solid foil targets with thicknesses in the micrometer range. Two different target geometries are presented and their proton beam deliverance characterized: cylindrical (∅ 5 μm) and planar (20 μm × 2 μm). In both cases typical Target Normal Sheath Acceleration emission patterns with exponential proton energy spectra are detected. Significantly higher proton numbers in laser-forward direction are observed when deploying the planar jet as compared to the cylindrical jet case. This is confirmed by two-dimensional Particle-in-Cell (2D3V PIC) simulations, which demonstrate that the planar jet proves favorable as its geometry leads to more optimized acceleration conditions.


Review of Scientific Instruments | 2012

A scintillator-based online detector for the angularly resolved measurement of laser-accelerated proton spectra.

Josefine Metzkes; Leonhard Karsch; S. D. Kraft; J. Pawelke; Christian Richter; M. Schürer; M. Sobiella; N. Stiller; K. Zeil; U. Schramm

In recent years, a new generation of high repetition rate (~10 Hz), high power (~100 TW) laser systems has stimulated intense research on laser-driven sources for fast protons. Considering experimental instrumentation, this development requires online diagnostics for protons to be added to the established offline detection tools such as solid state track detectors or radiochromic films. In this article, we present the design and characterization of a scintillator-based online detector that gives access to the angularly resolved proton distribution along one spatial dimension and resolves 10 different proton energy ranges. Conceived as an online detector for key parameters in laser-proton acceleration, such as the maximum proton energy and the angular distribution, the detector features a spatial resolution of ~1.3 mm and a spectral resolution better than 1.5 MeV for a maximum proton energy above 12 MeV in the current design. Regarding its areas of application, we consider the detector a useful complement to radiochromic films and Thomson parabola spectrometers, capable to give immediate feedback on the experimental performance. The detector was characterized at an electrostatic Van de Graaff tandetron accelerator and tested in a laser-proton acceleration experiment, proving its suitability as a diagnostic device for laser-accelerated protons.


Journal of Physics: Conference Series | 2017

First results with the novel petawatt laser acceleration facility in Dresden

U. Schramm; M. Bussmann; A. Irman; M. Siebold; K. Zeil; Daniel Albach; C Bernert; S. Bock; Florian-Emanuel Brack; J Branco; J. P. Couperus; T. E. Cowan; Alexander Debus; C Eisenmann; Marco Garten; Rene Gebhardt; S Grams; U. Helbig; Axel Huebl; T. Kluge; A. Köhler; Jakob Krämer; S. D. Kraft; F. Kroll; M. Kuntzsch; U. Lehnert; Markus Loeser; Josefine Metzkes; P. Michel; Lieselotte Obst

We report on first commissioning results of the DRACO Petawatt ultra-short pulse laser system implemented at the ELBE center for high power radiation sources of Helmholtz-Zentrum Dresden-Rossendorf. Key parameters of the laser system essential for efficient and reproducible performance of plasma accelerators are presented and discussed with the demonstration of 40 MeV proton acceleration under TNSA conditions as well as peaked electron spectra with unprecedented bunch charge in the 0.5 nC range.


Applied Physics Letters | 2017

High repetition rate, multi-MeV proton source from cryogenic hydrogen jets

Maxence Gauthier; Chandra Curry; S. Göde; Florian-Emanuel Brack; J. B. Kim; Michael MacDonald; Josefine Metzkes; Lieselotte Obst; Martin Rehwald; C. Rödel; H.-P. Schlenvoigt; Will Schumaker; U. Schramm; K. Zeil; S. H. Glenzer

We report on a high repetition rate proton source produced by high-intensity laser irradiation of a continuously flowing, cryogenic hydrogen jet. The proton energy spectra are recorded at 1 Hz for Draco laser powers of 6, 20, 40, and 100 TW. The source delivers ∼1013 protons/MeV/sr/min. We find that the average proton number over one minute, at energies sufficiently far from the cut-off energy, is robust to laser-target overlap and nearly constant. This work is therefore a first step towards pulsed laser-driven proton sources for time-resolved radiation damage studies and applications which require quasi-continuous doses at MeV energies.

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Dive into the Josefine Metzkes's collaboration.

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U. Schramm

Helmholtz-Zentrum Dresden-Rossendorf

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K. Zeil

Helmholtz-Zentrum Dresden-Rossendorf

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T. Kluge

Helmholtz-Zentrum Dresden-Rossendorf

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S. D. Kraft

Helmholtz-Zentrum Dresden-Rossendorf

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M. Bussmann

Helmholtz-Zentrum Dresden-Rossendorf

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T. E. Cowan

Helmholtz-Zentrum Dresden-Rossendorf

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Lieselotte Obst

Helmholtz-Zentrum Dresden-Rossendorf

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S. Bock

Helmholtz-Zentrum Dresden-Rossendorf

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Dustin Offermann

Los Alamos National Laboratory

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U. Helbig

Helmholtz-Zentrum Dresden-Rossendorf

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