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Publication
Featured researches published by Joseph Allico Djaman.
European journal of medicinal plants | 2015
Rita Bouagnon; Dodehe Yeo; Konan Kouassi; Kadja Beugre; Joseph Allico Djaman; Jean David N'guessan
Aim: Usually called Tea of Gambia, Lippia multiflora is traditionally used for its sedative, relaxing, febrifuge, anti-flu-like, antispasmodic, hypotensive, anti-inflammatory, anti-catarrhal, mucolytic, antiinfective and hepatoprotective properties. The present study was carried out to evaluate the hepatoprotective effect of aqueous extract of Lippia multiflora leaves against ethanol induced toxicity in rat livers. Study Design: Thirty Wistar albino rats (100-162 g) were divided into six groups of five animals. Original Research Article Bouagnon et al.; EJMP, 7(3): 146-155, 2015; Article no.EJMP.2015.077 147 Group 1 served as control and received only distilled water. Group 2 received only 15%ethanol (3 mL/100 g body weight/day). Group 3 served as standard group and received silymarin (70 mg/kg b.w.). Groups 4, 5 and 6 served as extract treatment groups and received respectively 100, 300 and 900 mg/kg of L. multiflora aqueous extract. 15% ethanol (3 mL/100 g b.w./day) was administered 1h after treatment in groups 3, 4, 5 and 6. Place and Duration of Study: The study was carried out in Laboratory of Biochemical Pharmacodynamy, Felix Houphouet-Boigny University of Cocody-Abidjan (Cote d’Ivoire) between September and November 2014. Methodology: All treatment protocols followed 28 days. Animals received daily doses and were observed for psychomotor changes and other signs of toxicity including death throughout the period of study. At days 7, 14, 21 and 28 of experimental period, blood samples were collected from retroorbital venous plexus in non-heparinized tubes and the serum levels of liver marker enzymes, biochemical metabolites and hematological parameters (numbers of red blood cells, white blood cells, platelet count and mean cell volume)were monitored. Results: L. multiflora extract (300 and 900 mg/kg b.w.) provides significant protection (P<0.05) against ethanol induced toxicity in rat livers showed by reduction of enzymatic parameters activities (ALT, AST and GGT). Histopathological study shows a normal hepatic architecture in L. multiflora extract (300 and 900 mg/kg b.w.) group compared to 15% ethanol group. Additionally, hematological analyses revealan increase of red blood cells and platelet count. A decrease of white blood cells and mean cell volume values in groups treated with 300 and 900 mg/kg of L. multiflora compared to 15% ethanol group is also observed. Conclusion: Our results prove that L. multiflora extract has protective effects against ethanolinduced toxicity.
BMC Complementary and Alternative Medicine | 2010
Souleymane Méité; Calixte Bahi; Dodehe Yeo; Jacques Y Datté; Joseph Allico Djaman; David Jean N'guessan
Journal of Applied Biosciences | 2013
Rubens Dinzedi Mbengui; Nathalie Guessennd; Gervais M. M’boh; Julien K. Golly; Constantin O. Okou; Jean David N'guessan; Mireille Dosso; Joseph Allico Djaman
Microbiology Research Journal International | 2018
Victoire Gadou; Nathalie Guessennd; Abalé Toty; Fernique Konan; Mohamed Ouattara; Mireille Dosso; Seydina M. Diene; Joseph Allico Djaman; Jean-Marc Rolain
International journal of Microbiology Research | 2018
Victoire Gadou; Seydina M. Diene; Jean Marc Rolain; Joseph Allico Djaman; Mireille Dosso; Nathalie Guessennd; Abalé Toty
International Journal of Research in Medical Sciences | 2018
Arsène M. Adon; Bognan A. A. J. Ackah; Guillaume Y. Yayé; Constantin O. Okou; Raoul K. K. Brahima; Joseph Allico Djaman
International Journal of Biochemistry Research and Review | 2017
Lydie Boyvin; Jeanne Aké; Kipré Laurent Séri; Gervais M’boh; Adou Francis Yapo; Joseph Allico Djaman
International journal of innovation and scientific research | 2016
Alain dit Philippe Bidie; Justine Wawa Tiekpa; Anatole Koutou; Jean David N'guessan; Joseph Allico Djaman
Der Pharmacia Lettre | 2016
Lydie Boyvin; Angele Edjeme-Ake; Gervais M’boh; Joseph Allico Djaman
International Journal of Phytomedicine | 2015
Nazaire Komenan Amani; Konan Kouassi; Rita Bouagnon; Philippe Alain Dit Bidie; Joseph Allico Djaman; David Jean N'guessan