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Dive into the research topics where Joseph C. Walsh is active.

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Featured researches published by Joseph C. Walsh.


Tetrahedron Letters | 1998

Completely diastereoselective radical reactions using arenechromium tricarbonyl complexes

Craig A. Merlic; Joseph C. Walsh

Reaction of chromium tricarbonyl complexed aryl aldehydes and ketones with samarium(II) iodide and methyl acrylate results in formation of cyclic lactones as single diastereomers. Complete diastereoselectivity is demonstrated with aldehydes and ketones α or β to the aromatic ring with radical coupling directed anti to the chromium tricarbonyl moiety.


Synthetic Communications | 2003

Selective and Practical Synthesis of Penciclovir

Tatsushi Toyokuni; Joseph C. Walsh; Mohammad Namavari; Shirin S. Shinde; Jennifer R. Moore; Jorge R. Barrio; Nagichettiar Satyamurthy

Abstract A selective and practical method has been developed for the synthesis of penciclovir (1) in gram quantities involving a highly N 9 selective alykylation of 2-amino-6-chloropurine (9) with 2-(2-phenyl-1,3-dioxane-5-yl)ethanol (12) as a key step.


Bioconjugate Chemistry | 2003

Synthesis of a new heterobifunctional linker, N-[4-(aminooxy)butyl]maleimide, for facile access to a thiol-reactive 18F-labeling agent.

Tatsushi Toyokuni; Joseph C. Walsh; Alan Dominguez; Michael E. Phelps; Jorge R. Barrio; Sanjiv S. Gambhir; Nagichettiar Satyamurthy


Journal of the American Chemical Society | 1999

Chemical Hermaphroditism: The Potential of the Cr(CO)3 Moiety To Stabilize Transition States and Intermediates with Anionic, Cationic, or Radical Character at the Benzylic Position

Craig A. Merlic; Joseph C. Walsh; and Dean J. Tantillo; K. N. Houk


Bioorganic & Medicinal Chemistry Letters | 2005

Synthesis of 4-(5-[18F]fluoromethyl-3-phenylisoxazol-4-yl)-benzenesulfonamide, a new [18F]fluorinated analogue of valdecoxib, as a potential radiotracer for imaging cyclooxygenase-2 with positron emission tomography

Tatsushi Toyokuni; J. S. Dileep Kumar; Joseph C. Walsh; Alan Shapiro; John J. Talley; Michael E. Phelps; Harvey R. Herschman; Jorge R. Barrio; Nagichettiar Satyamurthy


Journal of Organic Chemistry | 2001

The Tricarbonylchromium Template for Stereocontrol in Radical Reactions of Arenes

Craig A. Merlic; Joseph C. Walsh


Archive | 2006

In situ click chemistry method for screening high affinity molecular imaging probes

Hartmuth C. Kolb; Vani P. Mocharla; Joseph C. Walsh


Archive | 2007

Click chemistry-derived cyclic peptidomimetics as integrin markers

Hartmuth C. Kolb; Kai Chen; Joseph C. Walsh; Umesh B. Gangadharmath; Dhanalakshmi Kasi; Bing Wang; Brian A. Duclos; Qianwa Liang; Henry C. Padgett; Farhad Karimi


Archive | 2013

Verbindungen mit Matrix-Metalloproteinasehemmeraktivität und Abbildungsmittel dafür

Gang Chen; Umesh B. Gangadharmath; Dhanalakshmi Kasi; Hartmuth Kolb; Changhui Liu; Anjana Sinha; Joseph C. Walsh; Anna Katrin Szardenings; Eric Wang; Chul Yu; Wei Zhang; Klaus Kopka; Guenter Haufe; Michael Schaefers; Verena Hugenberg; Stefan Wagner; Sven Hermann; Hans-Joerg Breyholz; Andreas Faust


Archive | 2013

a Potential Apoptosis Imaging Agent, as Determined from PET/CT Scans in Healthy Volunteers

Mohan Doss; Hartmuth Kolb; Joseph C. Walsh; Vani P. Mocharla; Hong Fan; Ashok Chaudhary; Zhihong Zhu; R. Katherine Alpaugh; Miriam N. Lango; Jian Q. Yu

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Gang Chen

Janssen Pharmaceutica

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Wei Zhang

Avid Radiopharmaceuticals

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