Joseph D. Armstrong | Researchain

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Featured researches published by Joseph D. Armstrong.

Journal of Organic Chemistry | 1991

Stereochemical control in the ester enolate Claisen rearrangement. 1. Stereoselectivity in silyl ketene acetal formation

Robert E. Ireland; Peter Wipf; Joseph D. Armstrong

Journal of the American Chemical Society | 2009

Highly Efficient Asymmetric Synthesis of Sitagliptin

Karl B. Hansen; Yi Hsiao; Feng Xu; Nelo R. Rivera; Andrew M. Clausen; Michele Kubryk; Shane W. Krska; Thorsten Rosner; Bryon Simmons; Jaume Balsells; Nori Ikemoto; Yongkui Sun; Felix Spindler; Christophe Malan; Edward J. J. Grabowski; Joseph D. Armstrong

Journal of the American Chemical Society | 2004

Highly Efficient Synthesis of β-Amino Acid Derivatives via Asymmetric Hydrogenation of Unprotected Enamines

Yi Hsiao; Nelo R. Rivera; Thorsten Rosner; Shane W. Krska; Eugenia Njolito; Fang Wang; Yongkui Sun; Joseph D. Armstrong; Edward J. J. Grabowski; Richard D. Tillyer; Felix Spindler; Christophe Malan

Organic Process Research & Development | 2005

First Generation Process for the Preparation of the DPP-IV Inhibitor Sitagliptin

Karl B. Hansen; Jaume Balsells; Spencer D. Dreher; Yi Hsiao; Michele Kubryk; Michael Palucki; Nelo R. Rivera; Dietrich Steinhuebel; Joseph D. Armstrong; David Askin; Edward J. J. Grabowski

Archive | 2004

Novel crystalline forms of a phosphoric acid salt of a dipeptidyl peptidase-iv inhibitor

Robert M. Wenslow; Joseph D. Armstrong; Alex M. Chen; Stephen Howard Cypes; Russell R. Ferlita; Karl B. Hansen; Christopher M. Lindemann; Evangelia Spartalis

Archive | 2004

Process and intermediates for the preparation of beta-amino acid amide dipeptidyl peptidase-iv inhibitors

Remy Angelaud; Joseph D. Armstrong; David Askin; Jaume Balsells; Karl B. Hansen; Jaemoon Lee; Peter E. Maligres; Nelo R. Rivera; Yi Xiao; Yong-Li Zhong

Journal of Organic Chemistry | 2006

Proline-catalyzed, asymmetric mannich reactions in the synthesis of a DPP-IV inhibitor.

Jacob Janey; Yi Hsiao; Joseph D. Armstrong

Journal of the American Chemical Society | 2004

Mechanistic Evidence for an α-Oxoketene Pathway in the Formation of β-Ketoamides/Esters via Meldrum's Acid Adducts

Feng Xu; Joseph D. Armstrong; George X. Zhou; Bryon Simmons; David L. Hughes; Zhihong Ge; Edward J. J. Grabowski

Journal of the American Chemical Society | 2004

Highly diastereoselective heterogeneously catalyzed hydrogenation of enamines for the synthesis of chiral β-amino acid derivatives

Norihiro Ikemoto; David M. Tellers; Spencer D. Dreher; Jinchu Liu; Angie Huang; Nelo R. Rivera; Eugenia Njolito; Yi Hsiao; J. Christopher McWilliams; J. Michael Williams; Joseph D. Armstrong; Yongkui Sun; David J. Mathre; Edward J. J. Grabowski; Richard D. Tillyer

Organic Letters | 2005