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Dive into the research topics where Joseph G. Khoury is active.

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Featured researches published by Joseph G. Khoury.


Journal of Bone and Joint Surgery, American Volume | 2008

Predicting Scoliosis Progression from Skeletal Maturity: A Simplified Classification During Adolescence

James O. Sanders; Joseph G. Khoury; Shyam Kishan; Richard Browne; James F. Mooney; Kali D. Arnold; Sharon J. McConnell; Jeanne A. Bauman; David N. Finegold

BACKGROUND Both the Tanner-Whitehouse-III RUS score, which is based on the radiographic appearance of the epiphyses of the distal part of the radius, the distal part of the ulna, and small bones of the hand, and the digital skeletal age skeletal maturity scoring system, which is based on just the metacarpals and phalanges, correlate highly with the curve acceleration phase in girls with idiopathic scoliosis. However, these systems require an atlas and access to the scoring system, making their use impractical in a busy clinical setting. We sought to develop a simplified system that would correlate highly with scoliosis behavior but that would also be rapid and reliable for clinical practice. METHODS A simplified staging system involving the use of the Tanner-Whitehouse-III descriptors was developed. It was tested for intraobserver and interobserver reliability by six individuals on thirty skeletal age radiographs. The system was compared with the timing of the curve acceleration phase in a cohort of twenty-two girls with idiopathic scoliosis. RESULTS The average intraobserver unweighted kappa value was 0.88, and the average weighted kappa value was 0.96. The percentage of exact matches between readings for each rater was 89%, and 100% of the differences were within one unit. The average interobserver unweighted kappa value was 0.71, and the average weighted kappa value was 0.89. The percentage of exact matches between two reviewers was 71%, and 97% of the interobserver differences were within one stage or matched. The agreement was highest between the most experienced raters. Interobserver reliability was not improved by the use of a classification-specific atlas. The correlation of the staging system with the curve acceleration phase was 0.91. CONCLUSIONS The simplified skeletal maturity scoring system is reliable and correlates more strongly with the behavior of idiopathic scoliosis than the Risser sign or Greulich and Pyle skeletal ages do. The system has a modest learning curve but is easily used in a clinical setting and, in conjunction with curve type and magnitude, appears to be strongly prognostic of future scoliosis curve behavior.


Journal of Pediatric Orthopaedics | 2009

Derotational casting for progressive infantile scoliosis.

James O. Sanders; Jacques D'Astous; Marcie Fitzgerald; Joseph G. Khoury; Shyam Kishan; Peter F. Sturm

Background Serial cast correction by using the Cotrel derotation technique is one of several potential treatments for progressive infantile scoliosis. This study reviews our early experience to identify which, if any, patients are likely to benefit from or fail this technique. Methods We followed all patients treated at our institutions for progressive infantile scoliosis since 2003 prospectively at 1 institution and retrospectively at the other 2. Data, including etiology, Cobb angles, rib vertebral angle difference, Moe-Nash rotation, and space available for the lung, were recorded over time. Results Fifty-five patients with progressive infantile scoliosis had more than 1 year of follow-up from the initiation of casting. The diagnosis of progressive scoliosis was made based upon either a progressive Cobb angle or a rib vertebral angle difference of more than 20 degrees at presentation. All but 6 patients responded to cast correction. Nine patients have undergone surgery to date, 6 because of worsening and 3 by parent choice. As shown in the table, initiation of cast correction at a younger age, moderate curve size (<60 degrees), and an idiopathic diagnosis carry a better prognosis than an older age of initiation, curve >60 degrees, and a nonidiopathic diagnosis. The space available for the lung improved from 0.89 to 0.93. No patient experienced worsening of rib deformities. Conclusions Serial cast correction for infantile scoliosis often results in full correction in infants with idiopathic curves less than 60 degrees if started before 20 months of age. Cast correction for older patients with larger curves or nonidiopathic diagnosis still frequently results in curve improvement along with improvement in chest and body shape. Significance Derotational cast correction seems to play a role in the treatment of progressive infantile scoliosis with cures in young patients and reductions in curve size with a delay in surgery in older and syndromic patients. Level of Evidence Level 4, therapeutic study.


Journal of Pediatric Orthopaedics | 2007

Results of screw epiphysiodesis for the treatment of limb length discrepancy and angular deformity.

Joseph G. Khoury; Joao O. Tavares; Sharon McConnell; Gregory Zeiders; James O. Sanders

The purpose of this study was to evaluate the technique of screw epiphysiodesis for effectiveness, predictability, and reversibility. We reviewed the cases of our first 60 patients (105 physes) treated with percutaneous screw epiphysiodesis or hemiepiphysiodesis. All cases were followed up to maturity or screw removal if growth remained after full correction. A total of 30 patients underwent the procedure for limb length inequality. Final inequality was compared with the predicted epiphysiodesis effect. A total of 30patients (66 physes) underwent screw hemiepiphysiodesis for the correction of angular deformity. The degree of correction per month was calculated, the reversibility of the procedure was analyzed, and complications were evaluated. In the length group, at the end of treatment, the final limb length difference in the femur averaged 0.15 cm (SD, ±0.37 cm) from the epiphysiodesis effect predicted by using the multiplier method. In the tibia, this difference was 0.05 cm (SD, ±0.57 cm). In the angular group, the average correction in the distal femur was 6.91 degrees (SD, ±3.75 degrees) or 0.75 degrees per month (SD, ±0.45 degrees per month). In the proximal tibia, the average correction was 3.88 degrees (SD, ±3.57 degrees) or 0.37 degrees per month (SD, ±0.34 degrees per month). In all 13 cases where the screws were removed at the time of angular correction with significant growth remaining, growth resumed. Complications were minor and were related to incorrect placement of screws or minor hardware irritation. Percutaneous screw epiphysiodesis is a reliable, minimally invasive method with reliable results in both length and angular correction, with minimal morbidity, and with an acceptable complication rate.


Journal of Pediatric Orthopaedics | 2011

A prospective study on the effectiveness of cotton versus waterproof cast padding in maintaining the reduction of pediatric distal forearm fractures.

Christopher E. Robert; Jimmy J. Jiang; Joseph G. Khoury

Background Distal forearm fractures, one of the most common fractures seen in the pediatric population, are regularly treated by closed reduction and casting. Our study investigates the effectiveness of Gore-Tex-lined casting in maintaining the reduction of 100% displaced distal forearm fractures compared with traditional cotton-lined casts. Methods We screened all patients from February 2007 to July 2009 who presented to Childrens Hospital in Birmingham, AL with a distal radius fracture. Only patients with 100% displaced distal radius fractures were eligible to be assigned to either the cotton-lined or Gore-Tex-lined cast groups. Power analysis was performed to identify an adequate patient sample size. The mean maximum change between initial post-reduction x-rays and follow-up x-rays for anterior-posterior (AP) angulation, AP displacement, lateral angulation, and lateral displacement of the radius were calculated for both cotton and Gore-Tex groups. The rate of subsequent intervention and/or unacceptable results for each group was also analyzed. Results Seven hundred and twenty-two patients were treated with distal radius fractures at our hospital with 59 patients eligible for inclusion in our study. Thirty-six of our patients were treated with cotton-lined casts, and 23 patients were treated with Gore-Tex-lined cast. The mean maximum change in AP angulation, AP displacement, lateral angulation, and lateral displacement of the radius after initial reduction was 9.2 degrees, 6.9%, 13.9 degrees, and 13.6%, respectively, for the cotton-lined cast group and 7.7 degrees, 6.1%, 14.6 degrees, and 9.6%, respectively, for the Gore-Tex-lined cast group. There were no statistical differences between the means of the 4 measurements (P=0.33, 0.69, 0.73, and 0.10, respectively). There were also no significant differences between groups for final AP and lateral angulation and displacement. Subgroup analysis showed no significant differences in all measurements between cotton and Gore-Tex groups. Conclusion Gore-Tex and cotton-lined casts are equally effective in their ability to maintain the reduction of 100% displaced distal forearm fractures. Thus, Gore-Tex-lined casts can be offered to pediatric patients immediately after closed reduction of distal radius fractures of any severity. Level of Evidence Therapeutic level II.


Spine deformity | 2015

The Use of Chewing Gum Postoperatively in Pediatric Scoliosis Patients Facilitates an Earlier Return to Normal Bowel Function

Jonathan K. Jennings; J. Scott Doyle; Shawn Gilbert; Michael Conklin; Joseph G. Khoury

PURPOSE In surgical correction of scoliosis in pediatric patients, gastrointestinal complications including postoperative ileus can result in extended hospital stays, poorer pain management, slower progression with physical therapy, and overall decreased patient satisfaction. In patients undergoing gastrointestinal, gynecological, and urological surgery, gum chewing has been shown to reduce time to flatus and passage of feces. The authors hypothesized that chewing gum could also speed return to normal bowel function in pediatric patients undergoing surgical correction of scoliosis. METHODS The researchers obtained institutional review board approval for a prospective, randomized, controlled trial. Eligible patients included all adolescent idiopathic scoliosis patients undergoing posterior spinal fusion. Exclusion criteria included previous gastrointestinal surgery or preexisting gastrointestinal disease. Patients were randomized by coin flip. The treatment group chewed sugar-free bubble gum 5 times a day for 20 to 30 minutes beginning on postoperative day 1; the control group did not chew gum. Patients were asked a series of questions regarding subjective gastrointestinal symptoms each day. Time to flatus and first passage of feces were recorded as indicators of return to normal bowel function. Normality of data was assessed using normal probability plots. RESULTS A total of 83 patients completed the study (69 females and 14 males; mean age, 14.4 years). Of the 42 patients in the chewing gum group, 8 elected to stop chewing gum regularly before discharge for to a variety of reasons. Patients who chewed gum experienced first bowel movement on average 145.9 hours after surgery, 30.9 hours before those who did not chew gum (p = .04). Gum-chewing patients first experienced flatus an average of 55.2 hours after surgery, compared with 62.3 hours for controls. This trend did not reach statistical significance (p = .12). No difference was noted in duration of hospital stay, medications administered as required, or subjective symptoms. CONCLUSION Chewing gum after posterior spinal fusion for scoliosis is safe and may speed return of normal bowel function. Chewing gum after surgical correction of scoliosis facilitates an earlier return to normal bowel function, which may improve patient satisfaction in the early postoperative period.


Journal of Children's Orthopaedics | 2007

A technique for calculating limb length inequality and epiphyseodesis timing using the multiplier method and a spreadsheet

James O. Sanders; Joseph G. Khoury; Shyam Kishan

PurposeLimb length inequality and epiphyseodesis timing calculations are common in pediatric orthopedics. The multiplier method developed by Paley et al. has significantly simplified the calculation of ultimate limb length. The calculation of limb length inequality has also become very simple for congenital limb length inequalities. However, the equations for limb length inequality from acquired differences and epiphyseodesis timing are not simple, and are prone to arithmetic errors.MethodsTo limit these errors, we have developed a spreadsheet which finds the appropriate multipliers, solves the equations, and computes the predicted limb length inequality and the appropriate age for an epiphyseodesis.ResultsThis method of using a spreadsheet and the multiplier calculations is quite simple and quick to use in practice. The calculations can be cut and pasted into computerized charts for future reference.ConclusionsWe recommend this method for clinical use and make it available for public use.


Journal of Pediatric Orthopaedics B | 2014

Prospective evaluation of the use of Mitchell shoes and dynamic abduction brace for idiopathic clubfeet.

Chong Dy; Finberg Ns; Michael Conklin; Doyle Js; Joseph G. Khoury; Gilbert

Ponseti treatment for clubfoot has been successful, but recurrence continues to be an issue. After correction, patients are typically braced full time with a static abduction bar and shoes. Patient compliance with bracing is a modifiable risk factor for recurrence. We hypothesized that the use of Mitchell shoes and a dynamic abduction brace would increase compliance and thereby reduce the rate of recurrence. A prospective, randomized trial was carried out with consecutive patients treated for idiopathic clubfeet from 2008 to 2012. After casting and tenotomy, patients were randomized into either the dynamic or static abduction bar group. Both groups used Mitchell shoes. Patient demographics, satisfaction, and compliance were measured with self-reported questionnaires throughout follow-up. Thirty patients were followed up, with 15 in each group. Average follow-up was 18.7 months (range 3–40.7 months). Eight recurrences (26.7%) were found, with four in each group. Recurrences had a statistically significant higher number of casts and a longer follow-up time. Mean income, education level, patient-reported satisfaction and compliance, and age of caregiver tended to be lower in the recurrence group but were not statistically significant. No differences were found between the two brace types. Our study showed excellent patient satisfaction and reported compliance with Mitchell shoes and either the dynamic or static abduction bar. Close attention and careful education should be directed towards patients with known risk factors or difficult casting courses to maximize brace compliance, a modifiable risk factor for recurrence. Level of evidence II: prospective comparative study.


Journal of Surgical Education | 2017

Psychomotor Testing for Orthopedic Residency Applicants: A Pilot Study

Johnathan F. Williams; Shawna L. Watson; Dustin K. Baker; Brent A. Ponce; Gerald McGwin; Shawn Gilbert; Joseph G. Khoury

OBJECTIVE The purpose of this study was to develop an objective motor skills testing system to aid in the evaluation of potential orthopedic residents. DESIGN Participants attempted a battery of 5 motor skills tests (4 novel tests and the Grooved Pegboard [GPT] Test) in one 10-minute session. A percentile-based scoring system was created for each test based on raw scores. One-way analysis of variance was used to compare testing scores among 3 cohorts. Each novel test and overall scores were compared with GPT scores as a relative measure of validity. SETTING The 2015 orthopedic surgery residency interview season at an academic institution. PARTICIPANTS Thirty orthopedic residents and 72 nonresidents (15 community volunteers and 57 orthopedic surgery residency applicants). RESULTS Overall, residents performed better than nonresidents (p < 0.0001) and applicants performed worse than residents or volunteers (p < 0.0001). There were positive correlations between the GPT score and overall battery score (r = 0.63), screw and nut test (r = 0.40), and mimic a structure test (r = 0.26). The fracture reduction test and drilling test scores did not correlate to performance on the GPT. CONCLUSIONS Psychomotor testing for surgical applicants is an area in need of study. This investigation successfully piloted a novel battery of tests, which is easily reproducible and thus may be feasible for use in the orthopedic surgery residency interview setting. Longitudinal evaluation is required to explore correlation with future operative skill.


Clinical Orthopaedics and Related Research | 2014

CORR Insights®: Is Sternocleidomastoid Muscle Release Effective in Adults with Neglected Congenital Muscular Torticollis?

Joseph G. Khoury

This CORR Insights® is a commentary on the article “Is Sternocleidomastoid Muscle Release Effective in Adults With Neglected Congenital Muscular Torticollis?” by Lim and colleagues available at: DOI: 10.1007/s11999-013-3388-6. The author certifies that not he, nor any member of his immediate family, has funding or commercial associations (eg, consultancies, stock ownership, equity interest, patent/licensing arrangements, etc) that might pose a conflict of interest in connection with the submitted article. All ICMJE Conflict of Interest Forms for authors and Clinical Orthopaedics and Related Research ® editors and board members are on file with the publication and can be viewed on request. The opinions expressed are those of the writers, and do not reflect the opinion or policy of CORR ® or the Association of Bone and Joint Surgeons®. This CORR Insights® comment refers to the article available at DOI: 10.1007/s11999-013-3388-6.


Archive | 2013

Posterolateral Interspinal Fusion with Pedicle Screws

Joseph G. Khoury

The patient was properly identified by anesthesia, brought to the operating room, and positioned supine on the cart. General anesthetic was delivered and he was intubated. He was log-rolled onto the Wilson frame. All pressure points were padded. Antibiotics were given. The back was prepped and draped in the usual fashion. A midline incision was made over what was thought to be the L4/L5 level. Once the lumbar fascia was identified, dissection was carried down onto the appropriate level spinous process. A hemostat was placed between the spinous processes of L4 and L5 and its position was confirmed on a lateral radiograph which included the sacrum. Dissection was then carried down the lamina of L4 and L5 bilaterally to the level of the facet joints.

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Shyam Kishan

Loma Linda University Medical Center

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Shawn Gilbert

University of Alabama at Birmingham

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Gerald McGwin

University of Alabama at Birmingham

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Michael Conklin

University of Alabama at Birmingham

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Shawna L. Watson

University of Alabama at Birmingham

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Dustin K. Baker

University of Alabama at Birmingham

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