Joseph J. Nidiry

CURRENT CONCEPTS: ORGANOPHOSPHATE TOXICITY

Recent cases of nosocomial poisoning associated with the treatment of patients contaminated with organophosphate (OP) insecticides and the increasing potential for exposure to these chemicals elevate into sharper focus the continuing clinical and public health problem of pesticide poisoning. Despite a number of reports on the multiple aspects of OPs insecticides and their health effects, the general public and health services professionals, broadly defined, remain confused and misinformed about this class of chemicals. In this article we examine sources of exposure and current knowledge of health effects of OPs. The protection of health care workers is also discussed.

A 2 step procedure determined diagnosis in patients with unexplained weight loss

(2001) J Int Med 249, 41. Lankisch PG, Gerzmann M, Gerzmann JF, et al. . Unintentional weight loss: diagnosis and prognosis. The first prospective follow-up study from a secondary referral centre. . Jan; . : . –6 . [OpenUrl][1][PubMed][2][Web of Science][3] 
 QUESTION: In patients admitted to hospital with unexplained weight loss (≥5% of usual body weight), what are the relative frequencies of different causes? Cohort study with a mean follow up of 22 months. A secondary referral centre in Luneburg County, Germany. 158 patients who were ≥18 years of age (mean age 68 y, 56% women) and had a weight loss of ≥5% of usual body weight ≤6 months before being admitted to hospital. Exclusion criteria were weight loss from a known cause or voluntary weight loss. Follow up was complete. A 2 step diagnostic procedure was followed. While in the hospital, all patients received the first step: history and … [1]: {openurl}?query=rft.jtitle%253DJournal%2Bof%2Binternal%2Bmedicine%26rft.stitle%253DJ%2BIntern%2BMed%26rft.aulast%253DLankisch%26rft.auinit1%253DP.%26rft.volume%253D249%26rft.issue%253D1%26rft.spage%253D41%26rft.epage%253D46%26rft.atitle%253DUnintentional%2Bweight%2Bloss%253A%2Bdiagnosis%2Band%2Bprognosis.%2BThe%2Bfirst%2Bprospective%2Bfollow-up%2Bstudy%2Bfrom%2Ba%2Bsecondary%2Breferral%2Bcentre.%26rft_id%253Dinfo%253Apmid%252F11168783%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=11168783&link_type=MED&atom=%2Febmed%2F6%2F5%2F160.1.atom [3]: /lookup/external-ref?access_num=000167171000003&link_type=ISI

Diet and esophageal cancer: A case-control study

Abstract A case control study of osophageal cancer was conducted among black male and female residents of Washington, D.C., to assess the influence of the intake of food groups, alcohol, and smoking to the esophageal cancer. Twenty-three pairs (23 cases and 23 controls) were interviewed. Cases ate more pork (p

Peginterferon alpha-2a alone or combined with lamivudine increased response rates more than lamivudine alone.

Source Citation Marcellin P, Lau GK, Bonino F, et al. Peginterferon alfa-2a alone, lamivudine alone, and the two in combination in patients with HBeAg-negative chronic hepatitis B. N Engl J Med. 20...