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Joseph L. Goldstein

Alexion Pharmaceuticals

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Publication

Featured researches published by Joseph L. Goldstein.

Journal of Biological Chemistry | 1994

Assignment of the membrane attachment, DNA binding, and transcriptional activation domains of sterol regulatory element-binding protein-1 (SREBP-1).

Ryuichiro Sato; Jianxin Yang; Xiaodong Wang; Mark J. Evans; Y. K. Ho; Joseph L. Goldstein; Michael S. Brown

Archive | 2016

Regulatory role for hepatic low density lipoprotein receptors in vivo in the dog (cholesterol synthesis inhibitor/mevinolin/bile acid sequestrant/colestipol/catabolism of plasma lipoproteins)

Petri T. Kovanen; David W. Bilheimer; Joseph L. Goldstein; John J. Jaramillo; Michael S. Brown

Archive | 2016

Saturation and suppression of hepatic lipoprotein receptors: A mechanism for the hypercholesterolemia of cholesterol-fed rabbits (fi very low density lipoprotein/low density lipoprotein/apoproteins B and E/regulation of receptors/clearance of plasma lipoproteins)

Petri T. Kovanen; Michiael S. Brown; Sandip K. Basu; W. Bilheimer; Joseph L. Goldstein; Michael S. Brown

Archive | 2016

Increased mRNA for low density lipoprotein receptor in livers of rabbits treated with 17a-ethinyl estradiol (SI nuclease assay/regulation of cell surface receptors/cholesterol metabolism)

Patrick T.S. Ma; Tokuo Yamamoto; Joseph L. Goldstein; Michael S. Brown

Archive | 2016

Genetic Heterogeneity in Familial Hyperc Different Mutations Affecting Functions o (cholesterol metabolism/atherosclerosis/hyperlipidemia/l

Joseph L. Goldstein; Suzanna E. Dana; Y. Brunschede; Michael S. Brown

Archive | 2016

Familial Hypercholesterolemia: Defective Cultured Fibroblasts Associated with Imp 3-Hydroxy-3-Methylglutaryl Coenzyme A (cholesterol synthesis/hyperlipidemia/atheroselerosis/en:

Michael S. Brown; Joseph L. Goldstein

Archive | 2008

Supplemental Data Structure of N-terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol

Hyock Joo Kwon; Lina Abi-Mosleh; Michael L. Wang; Johann Deisenhofer; Joseph L. Goldstein; Michael S. Brown; Rodney E. Infante

Archive | 2008

Purified NPC1 Protein I.BINDINGOFCHOLESTEROLANDOXYSTEROLSTOA1278-AMINOACID MEMBRANEPROTEIN *

Rodney E. Infante; Lina Abi-Mosleh; Arun Radhakrishnan; Jarrod D. Dale; Michael S. Brown; Joseph L. Goldstein

Archive | 2007

Rnai-modulation von scap und ihre therapeutische verwendung

Juergen Soutschek; Pamela Tan; Jay D. Horton; Michael S. Brown; Joseph L. Goldstein; Young-Ah Moon

Archive | 2000

Method of inhibiting a farnesyl transferase enzyme

Michael S. Brown; Joseph L. Goldstein; Yuval Reiss

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Michael S. Brown

Alexion Pharmaceuticals

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Yuval Reiss

University of Texas Southwestern Medical Center

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Craig Crowley

Genentech

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David Oare

Genentech

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David W. Russell

University of Texas at Austin

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Guy L. James

Helen Hay Whitney Foundation

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James C. Marsters

Genentech

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Mark Reynolds

Genentech

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Robert Mcdowell

University of California

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Thomas E. Rawson

Genentech

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