Josephine S. Salser

Investigations on amino acids bound to DNA

Abstract A small but persistent amount (0.1–0.6 %) of amino acids is found bound to the DNA of all tissues examined. The amount is constant and reproducible for the DNA of a given tissue taken from animals of the same species, sex and age. These observations suggest that the residues have a role. There is a difference in absolute and relative amounts of the amino acids bound to DNA from different tissues of the same species. There are also differences among the amino acids bound to the DNA of the liver of several species.