Josephine Umoren

Effect of Beta-alanine Supplementation on the Onset of Blood Lactate Accumulation (OBLA) During Treadmill Running: Pre/post 2 Treatment Experimental Design

Backgroundβ-Alanine (βA) has been shown to improve performance during cycling. This study was the first to examine the effects of βA supplementation on the onset of blood lactate accumulation (OBLA) during incremental treadmill running.MethodsSeventeen recreationally-active men (mean ± SE 24.9 ± 4.7 yrs, 180.6 ± 8.9 cm, 79.25 ± 9.0 kg) participated in this randomized, double-blind, placebo-controlled pre/post test 2-treatment experimental design. Subjects participated in two incremental treadmill tests before and after 28 days of supplementation with either βA (6.0 g·d-1)(βA, n = 8) or an equivalent dose of Maltodextrin as the Placebo (PL, n = 9). Heart rate, percent heart rate maximum (%HRmax), %VO2max@OBLA (4.0 mmol.L-1 blood lactate concentration) and VO2max (L.min-1) were determined for each treadmill test. Friedman test was used to determine within group differences; and Mann-Whitney was used to determine between group differences for pre and post values (p < 0.05).ResultsThe βA group experienced a significant rightward shift in HR@OBLA beats.min-1 (p < 0.01) pre/post (161.6 ± 19.2 to 173.6 ± 9.9) but remained unchanged in the PL group (166.8 ± 15.8 to 169.6 ± 16.1). The %HRmax@OBLA increased (p < 0.05) pre/post in the βA group (83.0% ± 9.7 to 88.6% ± 3.7) versus no change in the PL group (86.3 ± % 4.8 to 87.9% ± 7.2). The %VO2max@OBLA increased (p < 0.05) in the βA group pre/post (69.1 ± 11.0 to 75.6 ± 10.7) but remained unchanged in the PL group (73.3 ± 7.3 to 74.3 ± 7.3). VO2max (L.min-1) decreased (p < 0.01) in the βA group pre/post (4.57 ± 0.8 to 4.31 ± 0.8) versus no change in the PL group (4.04 ± 0.7 to 4.18 ± 0.8). Body mass kg increased (p < 0.05) in the βA group pre/post (77.9 ± 9.0 to 78.3 ± 9.3) while the PL group was unchanged (80.6 ± 9.1 to 80.4 ± 9.0).ConclusionsβA supplementation for 28 days enhanced sub-maximal endurance performance by delaying OBLA. However, βA supplemented individuals had a reduced aerobic capacity as evidenced by the decrease in VO2max values post supplementation.

Risk Assessment of Arsenic in Rice Cereal and Other Dietary Sources for Infants and Toddlers in the U.S.

Currently, there are no set standards or quantitative guidelines available in the U.S. for arsenic levels in rice cereal, one of the most common first solid foods for infants. The objective of this study was to evaluate whether the detected levels of inorganic arsenic (Asi) in rice cereal in the U.S. market are safe for consumption by infants and toddlers. A risk assessment was conducted based on literature reviews of the reported Asi in rice cereal from the U.S. Food and Drug Administration’s (FDA) survey and the recommended daily intake of rice cereal by body weight, for infants and toddlers between four and 24 months old. As a part of risk management, a maximum contaminant level (MCL) for Asi in rice cereal was computed considering overall exposure sources including drinking water, infant formula, and other infant solid foods. Hazard quotients (HQs) for acute and chronic exposures were calculated based on the U.S. Agency for Toxic Substances and Disease Registry’s (ATSDR) Minimal Risk Level (MRL)acute (5.0 × 10−3 mg/kg/day) and MRLchronic (3.0 × 10−4 mg/kg/day). A cancer slope or potency factor of 1.5 mg/kg/day was used to predict an incremental lifetime cancer risk (ILCR). Exposure assessment showed that the largest source of Asi for infants and toddlers between four and 24 months old was rice cereal (55%), followed by other infant solid food (19%), and drinking water (18%). Infant formula was the smallest source of Asi for babies (9%) at the 50th percentile based on Monte Carlo simulations. While HQacute were consistently below 1.0, HQchronic at the 50 and 75th percentiles exceeded 1.0 for both rice cereal and total sources. ILCR ranged from 10−6 (50th) to 10−5 (75th percentile). MCLs for Asi in rice cereal ranged from 0.0 (chronic) to 0.4 mg/kg (acute exposures).

Serum Total Cholesterol and HDL-Cholesterol Levels as Associated with Copper and Zinc Intake in Physically Active and Sedentary Elderly Men and Women

The relationship of copper and zinc intake with serum total cholesterol, and HDL-cholesterol was studied in physically active and sedentary elderly men and women (N = 63). Three-day diet records over a period of twelve months and fasting blood samples were collected from each subject. Physical activity was associated with higher copper and zinc intakes, lower serum total cholesterol and higher serum copper levels. Higher copper intakes were associated with lower serum total cholesterol. Higher zinc intakes were associated with lower HDL-cholesterol levels. Higher copper serum levels were associated with lower serum total cholesterol. These results appeared inconsistent with the reports from animal studies. However, with it should be noted that the subjects in this study had copper and zinc intakes below the recommended dietary allowances and the calculated zinc to copper ratios were within the desired ranges.

Teachers' Self-Efficacy and Knowledge of Healthy Nutrition and Physical Activity Practices for Preschoolers: Instrument Development and Validation.

Childhood obesity remains a problem in the United States. Preschool teachers can help to attenuate it but need to have the confidence or self-efficacy to provide healthy practices. Therefore, the purpose of this study was to (a) develop and validate a preschool teacher self-efficacy tool to examine teachers’ confidence in addressing the nutrition and physical activity needs of children in their care and (b) examine relationships between teachers’ self-efficacy and knowledge of healthy nutrition and physical activity practices. Instrument design included examination of related literature and review by 12 subject matter experts. Two hundred seventy-three early childhood professionals submitted a 58-item questionnaire with 48 self-efficacy items in four domains of healthy practices for the preschool classroom; the remaining 10 items reflected knowledge of healthy practices. Two hundred fourteen professionals completed the questionnaire. A principle components factor analysis supported a five-factor self-efficacy scale (three of the original domains and one domain split into two factors) with 46 items. Knowledge of healthy practices and age of the professionals predicted overall self-efficacy. Results indicated evidence of validity for this new assessment tool to assess early childhood professionals’ self-efficacy toward healthy practices in preschool classrooms.

Racial and Ethnic Differences in Longitudinal Patterns of Family Mealtimes: Link to Adolescent Fruit and Vegetable Consumption.

Objective: To examine the longitudinal patterns of family mealtimes across racial/ethnic groups and to investigate whether the associations between longitudinal patterns of family mealtimes, baseline family and demographic characteristics, and healthy food consumption in adolescence differ by race/ethnicity. Methods: Data from the Early Childhood Longitudinal Study spanning from kindergarten to eighth grade were used for this study. Longitudinal patterns of family mealtimes and their link to baseline characteristics and healthy food consumption in adolescence, as defined by fruit and vegetable intakes, were determined using latent growth curves. Results: From childhood to adolescence, family mealtimes were stable among Asian families. Although Hispanic families displayed a downward pattern, mealtimes declined more steeply in non‐Hispanic white and black families. The links among family mealtimes, baseline characteristics, and healthy food consumption were not observed equally across racial/ethnic groups. Conclusions and Implications: Differences in longitudinal patterns of family mealtimes and in the association between family mealtimes and adolescent healthy food consumption across racial/ethnic groups call for targeted intervention in this nutritionally vulnerable period.

The Impact of High Diastase Malted Barley Flour on Weight and Height of Malnourished Children in Panama

ABSTRACT Enzymatic malted products reduce dietary bulk while maintaining nutrient density of cooked cereals. This study examined whether height/weight changes of malnourished Panamanian children fed oatmeal supplemented with high diastase malted barley flour were greater than for those fed unenhanced oatmeal. A pre-test/post-test control-group design was used, with random assignment to treatment/control groups. Treatment-group subjects gained more weight than did control-group subjects, both per day (t = 2.48, p = 0.016) and overall (t = 2.47, p = 0.016). Findings provide evidence that supplementation of oatmeal with malted barley improves nutritional status of malnourished children, as evidenced by weight gain.

Assessment of vitamin B12 tissue stores in elderly proton pump inhibitor users

Abstract Background: Adults over the age of 65 years are more prone to gastroesophageal reflux and, as such, are commonly prescribed proton pump inhibitors (PPIs). PPIs inhibit gastric acid secretion which can have adverse effects on vitamin B12 absorption. This quasi-experimental study was conducted to determine whether chronic use (≥1 year) of proton pump inhibitors (PPIs) results in decreased vitamin B12 in adults aged 68–94 years, as indicated by increased urinary methylmalonic acid (uM-MA). Methods: Fifteen men and women who had been using PPIs daily for a minimum of one year were recruited. Fifteen subjects not using PPIs were age (±3 years) and gender matched to the subjects taking PPIs. Tissue stores of vitamin B12 were determined using uM-MA. Results: The majority of subjects in this study resided in assisted care living facilities (55.66%) and the remaining subjects (43.33%) were free living. There were no significant differences in uM-MA levels between those using PPIs (Mdn = 1.1 μg uM-MA/mg creatinine), and those not using PPIs (Mdn = 1.1 μg uM-MA/mg creatinine) (p = 0.75). Conclusion: Chronic use of PPIs did not alter vitamin B12 in healthy individuals aged 68–94 years. Larger studies are indicated to validate these findings.